| UniProt ID | FRG1_MOUSE | |
|---|---|---|
| UniProt AC | P97376 | |
| Protein Name | Protein FRG1 | |
| Gene Name | Frg1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 258 | |
| Subcellular Localization | Nucleus, Cajal body . Nucleus, nucleolus . Cytoplasm . Cytoplasm, myofibril, sarcomere, Z line . Localization changes during myogenesis from mainly cytoplasmic in undifferentiated myoblasts, to strongly nucleolar in early myotubes and back to cytopla | |
| Protein Description | Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B.. | |
| Protein Sequence | MAEYSYVKSTKLVLKGTKAKSKKKKSKDKKRKREEDEETQLDIVGIWWTVSNFGEISGTIAIEMDKGAYIHALDNGLFTLGAPHREVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQDGKMALLASNSCFIRCNEAGDIEAKNKTAGEEEMIKIRSCAERETKKKDDIPEEDKGSVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MAEYSYVKSTK ----CCCCCCCHHHH | 8.86 | 20139300 | |
| 5 | Phosphorylation | ---MAEYSYVKSTKL ---CCCCCCCHHHHH | 18.24 | 20139300 | |
| 6 | Phosphorylation | --MAEYSYVKSTKLV --CCCCCCCHHHHHH | 15.82 | 20139300 | |
| 201 | Phosphorylation | IPEEDKGSVKQCEIN CCHHHCCCEEEEECE | 31.70 | 27600695 | |
| 209 | Phosphorylation | VKQCEINYVKKFQSF EEEEECEEEEECCHH | 21.21 | 29514104 | |
| 215 | Phosphorylation | NYVKKFQSFQDHKLK EEEEECCHHHHCCCC | 28.18 | 29176673 | |
| 228 | Phosphorylation | LKISKEDSKILKKAR CCCCHHHHHHHHHHH | 23.76 | 29176673 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FRG1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FRG1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FRG1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of FRG1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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