BZW2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BZW2_MOUSE
• UniProt AC: Q91VK1
• Protein Name: Basic leucine zipper and W2 domain-containing protein 2
• Gene Name: Bzw2
• Organism: Mus musculus (Mouse).
• Sequence Length: 419
• Protein Description: May be involved in neuronal differentiation..
• Protein Sequence: MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSEAEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELVLLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHAAKGKSVFLDQMKKFVEWLQNAEEESESEGEES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	KHQKPVLTGQRFKTR CCCCCCCCCCCCCCC	31.35	22817900
117	Acetylation	NYAQVFNKLIRRYKY HHHHHHHHHHHHHHH	33.55	-
205	Phosphorylation	KDANSVTSSLRKANL CCHHHHHHHHHHCCC	25.81	-
206	Phosphorylation	DANSVTSSLRKANLD CHHHHHHHHHHCCCC	23.87	-
389	Acetylation	YKEAHAAKGKSVFLD HHHHHHHCCCCHHHH	68.60	15609075
391	Acetylation	EAHAAKGKSVFLDQM HHHHHCCCCHHHHHH	42.62	15609083
412	Phosphorylation	LQNAEEESESEGEES HHHHHHHHHHCCCCC	50.10	27087446
414	Phosphorylation	NAEEESESEGEES-- HHHHHHHHCCCCC--	61.25	27087446
419	Phosphorylation	SESEGEES------- HHHCCCCC-------	41.02	27087446

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BZW2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BZW2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BZW2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of BZW2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteomic analysis of the developing mouse brain.";
Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.;
Mol. Cell. Proteomics 3:1093-1101(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-412 AND SER-414, ANDMASS SPECTROMETRY.
PubMed: 15345747