LITD1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LITD1_MOUSE
• UniProt AC: Q587J6
• Protein Name: LINE-1 type transposase domain-containing protein 1
• Gene Name: L1td1
• Organism: Mus musculus (Mouse).
• Sequence Length: 782
• Protein Sequence: MSGVQSKAARLQKERKEKLSADRERKTATSLCLKHSEVPASMMKQFNALMEMQEVMFAEMRETYKNDIKEMLLKRTAPWVKHLEERIGQQEGDAISERPKPGEKVEELSSGTDEDTENLTVRSKKGKQDKAKPLNSSHVLKSSLERGGEALRGEHGRCGESSSLVDWKNANEKPAREASCQSEENRLKAPKESPPEGGAGATLRLAADFSAATLDVGRQWSQVFRLLKEKELEPELQCSVKLAFKCDGEANVFSDLHSLRQFTSRKPFLRELLKDVFPQNEGGRRNELRERLGKTLGDTKHEARRIASDSLSFLFIKEVEVASPEVKTYKEETLDRKNKGTLKKQEGEEEEISETQGEETSEGETSELGEEEGSESEEEEESSESEEEEESSESAEEIGFISLVVDSESEEEVNRKTASQTKKKETFHGLKELAFSYLVWDSKKKKLVRCQEGGAAAASTQRIGMPCLTLYLTSPSESLGAGSDGPKSHSCTKLSALSQVTPLLTNIEKGRYKVPQTEEPTAKEADLILETEENFKRGVISVIRQMQREVDKIKNIYVSDVLNMKSSLDDLNSLACTIEARVSEQEDAVEGLTKDTMQLAREIVDKERLREREDRFRSSNIRVIGIPEKENRENGAVDIIKEVIEENFAELEDQSLEIVSAHRVPNSVDEHRLTPRHILVKFGSASDKQRVLKASRAKQEITYRGSKIRLTADLSPGTIDARSQWCGIIKILQDEGFQPRILYPAKLAFDFKGKTKIFFDIEEFKKFISDIPYLKDLLNNIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	SADRERKTATSLCLK CHHHHHHHHHHHHHH	41.19	28059163
30	Phosphorylation	RERKTATSLCLKHSE HHHHHHHHHHHHCCC	18.02	28833060
81	Ubiquitination	KRTAPWVKHLEERIG HHHHHHHHHHHHHHC	38.31	-
109	Phosphorylation	GEKVEELSSGTDEDT CCCHHHCCCCCCCCC	29.96	25293948
110	Phosphorylation	EKVEELSSGTDEDTE CCHHHCCCCCCCCCC	59.33	25293948
112	Phosphorylation	VEELSSGTDEDTENL HHHCCCCCCCCCCCC	37.86	25293948
116	Phosphorylation	SSGTDEDTENLTVRS CCCCCCCCCCCEECC	25.40	25293948
136	Phosphorylation	DKAKPLNSSHVLKSS CCCCCCCCHHHHHHH	29.51	-
308	Phosphorylation	HEARRIASDSLSFLF HHHHHHHHHCCCEEE	25.92	-
310	Phosphorylation	ARRIASDSLSFLFIK HHHHHHHCCCEEEEE	24.34	22006019
317	Ubiquitination	SLSFLFIKEVEVASP CCCEEEEEEEEECCC	48.66	-
323	Phosphorylation	IKEVEVASPEVKTYK EEEEEECCCCCCHHH	27.11	21149613
327	Ubiquitination	EVASPEVKTYKEETL EECCCCCCHHHHHHC	44.46	-
407	Phosphorylation	FISLVVDSESEEEVN CEEEEECCCCHHHHH	31.26	-
409	Phosphorylation	SLVVDSESEEEVNRK EEEECCCCHHHHHHH	55.02	-
442	Phosphorylation	FSYLVWDSKKKKLVR HHHHHCCCCCCEEEE	30.57	-
443	Ubiquitination	SYLVWDSKKKKLVRC HHHHCCCCCCEEEEC	67.16	-
478	Phosphorylation	YLTSPSESLGAGSDG EECCCHHHCCCCCCC	36.12	-
487	Ubiquitination	GAGSDGPKSHSCTKL CCCCCCCCCCCCHHH	67.35	-
490	Phosphorylation	SDGPKSHSCTKLSAL CCCCCCCCCHHHHHH	30.49	-
493	Ubiquitination	PKSHSCTKLSALSQV CCCCCCHHHHHHHHH	44.78	-
501	Phosphorylation	LSALSQVTPLLTNIE HHHHHHHHHHCHHHH	10.69	22006019
509	Ubiquitination	PLLTNIEKGRYKVPQ HHCHHHHCCCCCCCC	44.91	-
513	Ubiquitination	NIEKGRYKVPQTEEP HHHCCCCCCCCCCCC	46.18	-
523	Ubiquitination	QTEEPTAKEADLILE CCCCCCHHHCCEEEE	56.78	-
541	Phosphorylation	NFKRGVISVIRQMQR HHHHHHHHHHHHHHH	14.75	22006019
559	Phosphorylation	KIKNIYVSDVLNMKS HHHCEEHHHHHHCCC	12.67	-
566	Phosphorylation	SDVLNMKSSLDDLNS HHHHHCCCCHHHHHH	25.93	22006019
567	Phosphorylation	DVLNMKSSLDDLNSL HHHHCCCCHHHHHHH	30.24	-
583	Phosphorylation	CTIEARVSEQEDAVE HEHHHHHCCCHHHHC	28.19	22006019
594	Ubiquitination	DAVEGLTKDTMQLAR HHHCCCCHHHHHHHH	57.13	-
629	Ubiquitination	RVIGIPEKENRENGA EEECCCCHHCCCCCH	55.74	-
681	Acetylation	TPRHILVKFGSASDK CCCEEEEEECCHHHH	40.33	6566721
688	Ubiquitination	KFGSASDKQRVLKAS EECCHHHHHHHHHHH	37.19	-
715	Phosphorylation	IRLTADLSPGTIDAR EEEEEECCCCCCCHH	23.10	21149613
718	Phosphorylation	TADLSPGTIDARSQW EEECCCCCCCHHHHC	21.04	21149613
730	Ubiquitination	SQWCGIIKILQDEGF HHCCCHHHHHHCCCC	35.13	-
746	Ubiquitination	PRILYPAKLAFDFKG CCEEEEEEEEECCCC	35.52	-
752	Ubiquitination	AKLAFDFKGKTKIFF EEEEECCCCCEEEEE	62.43	-
765	Acetylation	FFDIEEFKKFISDIP EEEHHHHHHHHHHCH	50.48	30986483
765	Ubiquitination	FFDIEEFKKFISDIP EEEHHHHHHHHHHCH	50.48	-
766	Ubiquitination	FDIEEFKKFISDIPY EEHHHHHHHHHHCHH	53.93	-
775	Ubiquitination	ISDIPYLKDLLNNIH HHHCHHHHHHHHCCC	40.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LITD1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LITD1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LITD1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of LITD1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.