LRC40_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRC40_MOUSE
• UniProt AC: Q9CRC8
• Protein Name: Leucine-rich repeat-containing protein 40
• Gene Name: Lrrc40
• Organism: Mus musculus (Mouse).
• Sequence Length: 602
• Protein Sequence: MSRHMRAPRFDPRAGFHAEGKDRGPSVPQGLLKAARSSGQLNLAGRNLGEVPQCVWRINVDIPEEANQNLSFSSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTSLPSAIRELDNLQKLNVSHNKLKILPEEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIHAIATLKLLDYSDKQATLIPDDLFDATKTTLITSINFSKNQLCEIPQRIVELKEMVLDINLSFNKLSFISHELCLLQKLTFLDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPELGNCVQLRTLLLDGNPFRVPRAAILMKGTAAVLEYLRDRIPA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	GLLKAARSSGQLNLA HHHHHHHHCCCCCCC	33.81	25521595
38	Phosphorylation	LLKAARSSGQLNLAG HHHHHHHCCCCCCCC	25.63	26745281
54	Glutathionylation	NLGEVPQCVWRINVD CCCCCCCEEEEEECC	2.31	24333276
71	Phosphorylation	EEANQNLSFSSTERW HHHHCCCCCCCCCCC	30.54	26745281
73	Phosphorylation	ANQNLSFSSTERWWD HHCCCCCCCCCCCCC	32.73	26643407
74	Phosphorylation	NQNLSFSSTERWWDQ HCCCCCCCCCCCCCC	32.07	26643407
75	Phosphorylation	QNLSFSSTERWWDQT CCCCCCCCCCCCCCC	28.50	26643407
141	Ubiquitination	NVSHNKLKILPEEIT CCCCCCCCCCHHHHH	43.75	22790023
151	Ubiquitination	PEEITSLKNLRTLHL HHHHHHHCCCCHHCC	54.42	22790023
205	Phosphorylation	SLLRLNLSSNQLKNL HHHHHCCCCHHHHCC	26.60	-
358	Phosphorylation	REIIAKGTQEVLKYL HHHHHHCHHHHHHHH	22.35	29514104
364	Phosphorylation	GTQEVLKYLRSKIKD CHHHHHHHHHHHCCC	11.82	29514104
409	Acetylation	KLLDYSDKQATLIPD EECCCCCCCCEECCH	35.57	22902405
508	Ubiquitination	NLSFNRFKVFPEVLY ECCCCHHHCCHHHHH	39.46	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRC40_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRC40_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRC40_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of LRC40_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.