UniProt ID | NCOR2_MOUSE | |
---|---|---|
UniProt AC | Q9WU42 | |
Protein Name | Nuclear receptor corepressor 2 | |
Gene Name | Ncor2 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 2472 | |
Subcellular Localization | Nucleus. | |
Protein Description | Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.. | |
Protein Sequence | MSGSTQPVAQTWRAAEPRYPPHGISYPVQIARSHTDVGLLEYQHHPRDYTSHLSPGSIIQPQRRRPSLLSEFQPGSERSQELHLRPESRTFLPELGKPDIEFTESKRPRLELLPDTLLRPSPLLATGQPSGSEDLTKDRSLAGKLEPVSPPSPPHADPELELAPSRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQRFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMDDPMKVYKDRQVTNMWSEQERDTFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQMARSSQEEKEEKEKEKEADKEEEKQDAENEKEELSKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANHEETATPQQSSELASMEMNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKTPAAASEETAFPPAAEDEEMEASGASANEEELAEEAEASQASGNEVPRVGECSGPAAVNNSSDTESVPSPRSEATKDTGPKPTGTEALPAATQPPVPPPEEPAVAPAEPSPVPDASGPPSPEPSPSPAAPPATVDKDEQEAPAAPAPQTEDAKEQKSEAEEIDVGKPEEPEASEEPPESVKSDHKEETEEEPEDKAKGTEAIETVSEAPLKVEEAGSKAAVTKGSSSGATQDSDSSATCSADEVDEPEGGDKGRLLSPRPSLLTPAGDPRASTSPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDTVPPKPVPPVPPPTQHLQPEGDVSQQSGGSPRGKSRSPVPPAEKEAEKPAFFPAFPTEGPKLPTEPPRWSSGLPFPIPPREVIKTSPHAADPSAFSYTPPGHPLPLGLHDSARPVLPRPPISNPPPLISSAKHPGVLERQLGAISQQGMSVQLRVPHSEHAKAPMGPLTMGLPLAVDPKKLGTALGSATSGSITKGLPSTRAADGPSYRGSITHGTPADVLYKGTISRIVGEDSPSRLDRAREDTLPKGHVIYEGKKGHVLSYEGGMSVSQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRTVTSASIEGLMGRAIPEQHSPHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPPRDLTETYKPRPLDPLGPLKLKPTHEGVVATVKEAGRSIHEIPREELRRTPELPLAPRPLKEGSITQGTPLKYDSGAPSTGTKKHDVRSIIGSPGRPFPALHPLDIMADARALERACYEESLKSRSGTSSGAGGSITRGAPVVVPELGKPRQSPLTYEDHGAPFTSHLPRGSPVTTREPTPRLQEGSLLSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVTGVDLYRGHIPLAFDPTSIPRGIPLEAAAAAYYLPRHLAPSPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAASAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAIDRLAYLPTAPPPFSSRHSSSPLSPGGPTHLAKPTATSSSERERERERERDKSILTSTTTVEHAPIWRPGTEQSSGAGGSSRPASHTHQHSPISPRTQDALQQRPSVLHNTSMKGVVTSVEPGTPTVLRWARSTSTSSPVRPAATFPPATHCPLGGTLEGVYPTLMEPVLLPKETSRVARPERPRVDAGHAFLTKPPAREPASSPSKSSEPRSLAPPSSSHTAIARTPAKNLAPHHASPDPPAPTSASDLHREKTQSKPFSIQELELRSLGYHSGAGYSPDGVEPISPVSSPSLTHDKGLSKPLEELEKSHLEGELRHKQPGPMKLSAEAAHLPHLRPLPESQPSSSPLLQTAPGIKGHQRVVTLAQHISEVITQDYTRHHPQQLSGPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGTPARGSPHSEGGKRSPEPSKTSVLGSSEDAIEPVSPPEGMTEPGHARSTAYPLLYRDGEQGEPRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNIGQPGTEIFNMPAITGAGLMTCRSQAVQEHASTNMGLEAIIRKALMGKYDQWEEPPPLGANAFNPLNASASLPAAAMPITTADGRSDHALTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLAAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
18 | Asymmetric dimethylarginine | TWRAAEPRYPPHGIS HHHHCCCCCCCCCCC | 48.36 | - | |
18 | Methylation | TWRAAEPRYPPHGIS HHHHCCCCCCCCCCC | 48.36 | 24129315 | |
33 | Phosphorylation | YPVQIARSHTDVGLL CCHHCCCCCCCCCCE | 23.01 | 17203969 | |
35 | Phosphorylation | VQIARSHTDVGLLEY HHCCCCCCCCCCEEE | 33.36 | 17203969 | |
49 | Phosphorylation | YQHHPRDYTSHLSPG ECCCCCCCCCCCCCC | 16.06 | 25777480 | |
50 | Phosphorylation | QHHPRDYTSHLSPGS CCCCCCCCCCCCCCC | 17.60 | 26643407 | |
51 | Phosphorylation | HHPRDYTSHLSPGSI CCCCCCCCCCCCCCC | 19.05 | 26643407 | |
54 | Phosphorylation | RDYTSHLSPGSIIQP CCCCCCCCCCCCCCC | 23.07 | 25266776 | |
57 | Phosphorylation | TSHLSPGSIIQPQRR CCCCCCCCCCCCCCC | 21.65 | 26643407 | |
67 | Phosphorylation | QPQRRRPSLLSEFQP CCCCCCCHHHHCCCC | 39.88 | 25521595 | |
70 | Phosphorylation | RRRPSLLSEFQPGSE CCCCHHHHCCCCCCC | 41.48 | 25619855 | |
76 | Phosphorylation | LSEFQPGSERSQELH HHCCCCCCCCCCCEE | 36.20 | 25619855 | |
88 | Phosphorylation | ELHLRPESRTFLPEL CEECCHHHCCCCHHH | 39.02 | 24899341 | |
121 | Phosphorylation | PDTLLRPSPLLATGQ CCCCCCCCCCCCCCC | 23.03 | 26643407 | |
140 | Phosphorylation | EDLTKDRSLAGKLEP CCCCCCHHHCCCCEE | 32.48 | 25619855 | |
149 | Phosphorylation | AGKLEPVSPPSPPHA CCCCEECCCCCCCCC | 41.63 | 25521595 | |
152 | Phosphorylation | LEPVSPPSPPHADPE CEECCCCCCCCCCCC | 55.22 | 25521595 | |
165 | Phosphorylation | PELELAPSRLSKEEL CCCCCCCCCCCHHHH | 40.00 | 25619855 | |
215 | Phosphorylation | PEPEKPVSPPPIESK CCCCCCCCCCCCCCH | 39.97 | 25521595 | |
221 | Phosphorylation | VSPPPIESKHRSLVQ CCCCCCCCHHHHHHH | 34.19 | 25619855 | |
335 | Acetylation | KVREYYEKQFPEIRK HHHHHHHHHCHHHHH | 40.91 | 23806337 | |
359 | Phosphorylation | SRVGQRGSGLSMSAA HHHHHCCCCCCHHHH | 38.46 | 29514104 | |
362 | Phosphorylation | GQRGSGLSMSAARSE HHCCCCCCHHHHHCH | 17.76 | 25338131 | |
387 | Ubiquitination | SEQENLEKQMRQLAV HHHHHHHHHHHHHCC | 53.19 | - | |
449 | Acetylation | EKFMQHPKNFGLIAS HHHHHCCCCHHHHHH | 63.88 | 7610239 | |
456 | Phosphorylation | KNFGLIASFLERKTV CCHHHHHHHHHHHHH | 24.30 | 21149613 | |
493 | Phosphorylation | SYRRRGKSQQQQQQQ HHHHHCHHHHHHHHH | 35.73 | 29514104 | |
511 | Phosphorylation | QQQQMARSSQEEKEE HHHHHHHHHHHHHHH | 27.17 | 29899451 | |
546 | Phosphorylation | EELSKEKTDDTSGED HHHHHHHCCCCCCCC | 39.95 | 25159016 | |
549 | Phosphorylation | SKEKTDDTSGEDNDE HHHHCCCCCCCCCHH | 41.25 | 27087446 | |
550 | Phosphorylation | KEKTDDTSGEDNDEK HHHCCCCCCCCCHHH | 47.37 | 27087446 | |
562 | Phosphorylation | DEKEAVASKGRKTAN HHHHHHHHHCCCCCC | 29.10 | 25777480 | |
581 | Phosphorylation | RKGRITRSMANEANH HHCHHCHHHHHHCCC | 17.38 | 25338131 | |
668 | Sumoylation | ILQQHKLKMEKERNA HHHHHHHHHHHHHHH | 50.22 | - | |
668 | Sumoylation | ILQQHKLKMEKERNA HHHHHHHHHHHHHHH | 50.22 | - | |
704 | Phosphorylation | EDEEMEASGASANEE CCHHHHHHCCCCCHH | 22.91 | 29514104 | |
707 | Phosphorylation | EMEASGASANEEELA HHHHHCCCCCHHHHH | 34.84 | 25263469 | |
734 | Phosphorylation | VPRVGECSGPAAVNN CCCCCCCCCCCCCCC | 43.43 | 25619855 | |
742 | Phosphorylation | GPAAVNNSSDTESVP CCCCCCCCCCCCCCC | 25.12 | 27087446 | |
743 | Phosphorylation | PAAVNNSSDTESVPS CCCCCCCCCCCCCCC | 51.15 | 25521595 | |
745 | Phosphorylation | AVNNSSDTESVPSPR CCCCCCCCCCCCCCC | 31.91 | 25521595 | |
747 | Phosphorylation | NNSSDTESVPSPRSE CCCCCCCCCCCCCCC | 41.23 | 25521595 | |
750 | Phosphorylation | SDTESVPSPRSEATK CCCCCCCCCCCCCCC | 30.69 | 25521595 | |
753 | Phosphorylation | ESVPSPRSEATKDTG CCCCCCCCCCCCCCC | 34.66 | 26643407 | |
756 | Phosphorylation | PSPRSEATKDTGPKP CCCCCCCCCCCCCCC | 25.96 | 23984901 | |
838 | Phosphorylation | EDAKEQKSEAEEIDV HHHHHHHHHHHHCCC | 41.56 | 23684622 | |
854 | Phosphorylation | KPEEPEASEEPPESV CCCCCCCCCCCCHHH | 40.61 | 29550500 | |
860 | Phosphorylation | ASEEPPESVKSDHKE CCCCCCHHHCCCCHH | 40.39 | 23375375 | |
863 | Phosphorylation | EPPESVKSDHKEETE CCCHHHCCCCHHHCC | 42.67 | 25521595 | |
869 | Phosphorylation | KSDHKEETEEEPEDK CCCCHHHCCCCCCHH | 50.19 | 23375375 | |
878 | Acetylation | EEPEDKAKGTEAIET CCCCHHHHCCHHHHH | 72.59 | - | |
898 | Phosphorylation | LKVEEAGSKAAVTKG EEHHHHCCCEEEECC | 26.60 | 23811945 | |
906 | Phosphorylation | KAAVTKGSSSGATQD CEEEECCCCCCCCCC | 23.92 | 25619855 | |
907 | Phosphorylation | AAVTKGSSSGATQDS EEEECCCCCCCCCCC | 41.27 | 25619855 | |
908 | Phosphorylation | AVTKGSSSGATQDSD EEECCCCCCCCCCCC | 33.86 | 25619855 | |
911 | Phosphorylation | KGSSSGATQDSDSSA CCCCCCCCCCCCCCC | 36.11 | 25619855 | |
914 | Phosphorylation | SSGATQDSDSSATCS CCCCCCCCCCCCEEC | 29.58 | 25619855 | |
916 | Phosphorylation | GATQDSDSSATCSAD CCCCCCCCCCEECCC | 26.31 | 25619855 | |
917 | Phosphorylation | ATQDSDSSATCSADE CCCCCCCCCEECCCC | 32.37 | 25619855 | |
919 | Phosphorylation | QDSDSSATCSADEVD CCCCCCCEECCCCCC | 14.67 | 25619855 | |
921 | Phosphorylation | SDSSATCSADEVDEP CCCCCEECCCCCCCC | 34.11 | 25619855 | |
938 | Phosphorylation | GDKGRLLSPRPSLLT CCCCCCCCCCCHHCC | 24.37 | 26824392 | |
942 | Phosphorylation | RLLSPRPSLLTPAGD CCCCCCCHHCCCCCC | 36.97 | 26824392 | |
945 | Phosphorylation | SPRPSLLTPAGDPRA CCCCHHCCCCCCCCC | 19.18 | 24068923 | |
953 | Phosphorylation | PAGDPRASTSPQKPL CCCCCCCCCCCCCCC | 30.60 | 27742792 | |
954 | Phosphorylation | AGDPRASTSPQKPLD CCCCCCCCCCCCCCC | 43.36 | 26824392 | |
955 | Phosphorylation | GDPRASTSPQKPLDL CCCCCCCCCCCCCCH | 23.88 | 26824392 | |
958 | Acetylation | RASTSPQKPLDLKQL CCCCCCCCCCCHHHH | 51.43 | 22826441 | |
987 | Phosphorylation | HEPPREDTVPPKPVP CCCCCCCCCCCCCCC | 30.11 | 25777480 | |
1000 | Phosphorylation | VPPVPPPTQHLQPEG CCCCCCCCCCCCCCC | 34.10 | 26643407 | |
1004 | Phosphorylation | PPPTQHLQPEGDVSQ CCCCCCCCCCCCCCC | 31.69 | - | |
1010 | Phosphorylation | LQPEGDVSQQSGGSP CCCCCCCCCCCCCCC | 27.52 | 25266776 | |
1013 | Phosphorylation | EGDVSQQSGGSPRGK CCCCCCCCCCCCCCC | 37.17 | 26643407 | |
1014 | Phosphorylation | GDVSQQSGGSPRGKS CCCCCCCCCCCCCCC | 35.94 | - | |
1016 | Phosphorylation | VSQQSGGSPRGKSRS CCCCCCCCCCCCCCC | 18.23 | 26824392 | |
1019 | Phosphorylation | QSGGSPRGKSRSPVP CCCCCCCCCCCCCCC | 35.36 | - | |
1021 | Phosphorylation | GGSPRGKSRSPVPPA CCCCCCCCCCCCCCC | 40.59 | 27087446 | |
1023 | Phosphorylation | SPRGKSRSPVPPAEK CCCCCCCCCCCCCHH | 37.02 | 27087446 | |
1071 | Phosphorylation | PPREVIKTSPHAADP CCHHHHCCCCCCCCC | 36.04 | 25338131 | |
1155 | Phosphorylation | KAPMGPLTMGLPLAV CCCCCCCCCCCCEEE | 16.60 | 22942356 | |
1181 | Acetylation | ATSGSITKGLPSTRA CCCCCCCCCCCCCCC | 57.70 | - | |
1209 | Acetylation | TPADVLYKGTISRIV CCHHHEEEEHHHHHH | 45.47 | - | |
1220 | Phosphorylation | SRIVGEDSPSRLDRA HHHHCCCCHHHHHHH | 22.07 | 25521595 | |
1222 | Phosphorylation | IVGEDSPSRLDRARE HHCCCCHHHHHHHHH | 49.80 | 23984901 | |
1239 | Phosphorylation | LPKGHVIYEGKKGHV CCCCCEEEECCCCCE | 19.96 | 25367039 | |
1265 | Phosphorylation | CSKEDGRSSSGPPHE CCCCCCCCCCCCCCC | 34.09 | 29899451 | |
1266 | Phosphorylation | SKEDGRSSSGPPHET CCCCCCCCCCCCCCC | 37.64 | 26824392 | |
1267 | Phosphorylation | KEDGRSSSGPPHETA CCCCCCCCCCCCCCC | 57.47 | 29899451 | |
1273 | Phosphorylation | SSGPPHETAAPKRTY CCCCCCCCCCCCCCC | 25.70 | 23984901 | |
1293 | Phosphorylation | RVGRTVTSASIEGLM CCCCCCCHHHHHHHH | 18.71 | 29514104 | |
1309 | Phosphorylation | RAIPEQHSPHLKEQH CCCCCCCCHHHHHHH | 17.45 | 25521595 | |
1350 | Phosphorylation | KLLKREGTPPPPPPP HHHHCCCCCCCCCCC | 28.06 | 27087446 | |
1361 | Phosphorylation | PPPPRDLTETYKPRP CCCCCCCCCCCCCCC | 30.48 | 26643407 | |
1363 | Phosphorylation | PPRDLTETYKPRPLD CCCCCCCCCCCCCCC | 31.45 | 26643407 | |
1364 | Phosphorylation | PRDLTETYKPRPLDP CCCCCCCCCCCCCCC | 16.86 | 26643407 | |
1406 | Phosphorylation | PREELRRTPELPLAP CHHHHCCCCCCCCCC | 18.06 | 26824392 | |
1420 | Phosphorylation | PRPLKEGSITQGTPL CCCCCCCCCCCCCCC | 24.45 | 23984901 | |
1422 | Phosphorylation | PLKEGSITQGTPLKY CCCCCCCCCCCCCEE | 23.73 | 23984901 | |
1425 | Phosphorylation | EGSITQGTPLKYDSG CCCCCCCCCCEECCC | 18.68 | 26643407 | |
1429 | Phosphorylation | TQGTPLKYDSGAPST CCCCCCEECCCCCCC | 24.03 | 22817900 | |
1436 | Phosphorylation | YDSGAPSTGTKKHDV ECCCCCCCCCCCCHH | 48.05 | 22817900 | |
1438 | Phosphorylation | SGAPSTGTKKHDVRS CCCCCCCCCCCHHHH | 36.69 | 22817900 | |
1445 | Phosphorylation | TKKHDVRSIIGSPGR CCCCHHHHHHCCCCC | 20.57 | 21082442 | |
1449 | Phosphorylation | DVRSIIGSPGRPFPA HHHHHHCCCCCCCCC | 17.48 | 26824392 | |
1505 | Acetylation | VVVPELGKPRQSPLT EECCCCCCCCCCCCC | 50.04 | 23236377 | |
1509 | Phosphorylation | ELGKPRQSPLTYEDH CCCCCCCCCCCCCCC | 24.13 | 27180971 | |
1512 | Phosphorylation | KPRQSPLTYEDHGAP CCCCCCCCCCCCCCC | 28.40 | 26160508 | |
1513 | Phosphorylation | PRQSPLTYEDHGAPF CCCCCCCCCCCCCCC | 27.35 | 26643407 | |
1521 | Phosphorylation | EDHGAPFTSHLPRGS CCCCCCCCCCCCCCC | 17.74 | 26643407 | |
1522 | Phosphorylation | DHGAPFTSHLPRGSP CCCCCCCCCCCCCCC | 24.33 | 26643407 | |
1528 | Phosphorylation | TSHLPRGSPVTTREP CCCCCCCCCCCCCCC | 19.92 | 24899341 | |
1532 | O-linked_Glycosylation | PRGSPVTTREPTPRL CCCCCCCCCCCCCCC | 33.01 | 30059200 | |
1532 | Phosphorylation | PRGSPVTTREPTPRL CCCCCCCCCCCCCCC | 33.01 | - | |
1536 | Phosphorylation | PVTTREPTPRLQEGS CCCCCCCCCCCCCCC | 19.11 | 24899341 | |
1550 | Phosphorylation | SLLSSKASQDRKLTS CCCCCCHHCCCCCCC | 36.03 | 25338131 | |
1556 | Phosphorylation | ASQDRKLTSTPREIA HHCCCCCCCCHHHHH | 33.32 | 29550500 | |
1557 | Phosphorylation | SQDRKLTSTPREIAK HCCCCCCCCHHHHHC | 47.02 | 29550500 | |
1558 | Phosphorylation | QDRKLTSTPREIAKS CCCCCCCCHHHHHCC | 22.56 | 29550500 | |
1565 | Phosphorylation | TPREIAKSPHSTVPE CHHHHHCCCCCCCCC | 20.87 | 21082442 | |
1568 | Phosphorylation | EIAKSPHSTVPEHHP HHHCCCCCCCCCCCC | 34.19 | 25266776 | |
1569 | Phosphorylation | IAKSPHSTVPEHHPH HHCCCCCCCCCCCCC | 36.73 | 25266776 | |
1579 | Phosphorylation | EHHPHPISPYEHLLR CCCCCCCCHHHHHHC | 26.36 | 22817900 | |
1581 | Phosphorylation | HPHPISPYEHLLRGV CCCCCCHHHHHHCCC | 14.80 | 22817900 | |
1595 | Methylation | VTGVDLYRGHIPLAF CCCCCCCCCCCCCCC | 37.19 | 18958591 | |
1609 | Methylation | FDPTSIPRGIPLEAA CCCCCCCCCCCHHHH | 54.74 | 58859587 | |
1624 | Asymmetric dimethylarginine | AAAYYLPRHLAPSPT HHHHHCHHHCCCCCC | 34.55 | - | |
1624 | Methylation | AAAYYLPRHLAPSPT HHHHHCHHHCCCCCC | 34.55 | 80702849 | |
1629 | Phosphorylation | LPRHLAPSPTYPHLY CHHHCCCCCCCCCCC | 25.02 | 26643407 | |
1631 | Phosphorylation | RHLAPSPTYPHLYPP HHCCCCCCCCCCCCC | 54.76 | 26643407 | |
1632 | Phosphorylation | HLAPSPTYPHLYPPY HCCCCCCCCCCCCCC | 7.64 | 26643407 | |
1672 | Phosphorylation | QMHHNAASAMAQRAD HHHHHHHHHHHHHHH | 19.03 | 29899451 | |
1682 | Methylation | AQRADMLRGLSPRES HHHHHHHCCCCHHHH | 37.05 | 12018119 | |
1685 | Phosphorylation | ADMLRGLSPRESSLA HHHHCCCCHHHHHHH | 25.41 | 29514104 | |
1718 | Phosphorylation | LPVLVPPTPGTPATA CCEECCCCCCCCCCH | 28.42 | 22028470 | |
1721 | Phosphorylation | LVPPTPGTPATAIDR ECCCCCCCCCCHHHH | 15.79 | 29514104 | |
1744 | Phosphorylation | PPFSSRHSSSPLSPG CCCCCCCCCCCCCCC | 31.25 | 26160508 | |
1745 | Phosphorylation | PFSSRHSSSPLSPGG CCCCCCCCCCCCCCC | 29.83 | 21082442 | |
1746 | Phosphorylation | FSSRHSSSPLSPGGP CCCCCCCCCCCCCCC | 32.64 | 26824392 | |
1749 | Phosphorylation | RHSSSPLSPGGPTHL CCCCCCCCCCCCCCC | 25.53 | 26824392 | |
1754 | Phosphorylation | PLSPGGPTHLAKPTA CCCCCCCCCCCCCCC | 32.56 | 25266776 | |
1760 | Phosphorylation | PTHLAKPTATSSSER CCCCCCCCCCCHHHH | 41.69 | 20531401 | |
1762 | Phosphorylation | HLAKPTATSSSERER CCCCCCCCCHHHHHH | 31.45 | 20531401 | |
1763 | Phosphorylation | LAKPTATSSSERERE CCCCCCCCHHHHHHH | 29.42 | 20531401 | |
1764 | Phosphorylation | AKPTATSSSERERER CCCCCCCHHHHHHHH | 31.68 | 20415495 | |
1765 | Phosphorylation | KPTATSSSERERERE CCCCCCHHHHHHHHH | 40.20 | 20415495 | |
1810 | Phosphorylation | GGSSRPASHTHQHSP CCCCCCCCCCCCCCC | 31.44 | 23684622 | |
1812 | Phosphorylation | SSRPASHTHQHSPIS CCCCCCCCCCCCCCC | 22.27 | 28418008 | |
1816 | Phosphorylation | ASHTHQHSPISPRTQ CCCCCCCCCCCHHHH | 19.84 | 26824392 | |
1819 | Phosphorylation | THQHSPISPRTQDAL CCCCCCCCHHHHHHH | 16.24 | 26824392 | |
1822 | O-linked_Glycosylation | HSPISPRTQDALQQR CCCCCHHHHHHHHHC | 33.90 | 55413933 | |
1822 | Phosphorylation | HSPISPRTQDALQQR CCCCCHHHHHHHHHC | 33.90 | - | |
1843 | O-linked_Glycosylation | TSMKGVVTSVEPGTP CCCCEEEEEECCCCC | 25.34 | 30059200 | |
1843 | Phosphorylation | TSMKGVVTSVEPGTP CCCCEEEEEECCCCC | 25.34 | - | |
1844 | O-linked_Glycosylation | SMKGVVTSVEPGTPT CCCEEEEEECCCCCC | 16.93 | 30059200 | |
1844 | Phosphorylation | SMKGVVTSVEPGTPT CCCEEEEEECCCCCC | 16.93 | 29514104 | |
1849 | Phosphorylation | VTSVEPGTPTVLRWA EEEECCCCCCEEHHH | 26.88 | 26239621 | |
1851 | Phosphorylation | SVEPGTPTVLRWARS EECCCCCCEEHHHHC | 31.82 | 28066266 | |
1854 | Methylation | PGTPTVLRWARSTST CCCCCEEHHHHCCCC | 22.22 | 24129315 | |
1858 | Phosphorylation | TVLRWARSTSTSSPV CEEHHHHCCCCCCCC | 20.97 | 26060331 | |
1859 | Phosphorylation | VLRWARSTSTSSPVR EEHHHHCCCCCCCCC | 30.39 | 26060331 | |
1860 | Phosphorylation | LRWARSTSTSSPVRP EHHHHCCCCCCCCCC | 27.78 | 26060331 | |
1861 | Phosphorylation | RWARSTSTSSPVRPA HHHHCCCCCCCCCCC | 33.06 | 26060331 | |
1862 | Phosphorylation | WARSTSTSSPVRPAA HHHCCCCCCCCCCCC | 32.20 | 26060331 | |
1863 | Phosphorylation | ARSTSTSSPVRPAAT HHCCCCCCCCCCCCC | 27.74 | 23384938 | |
1919 | Phosphorylation | DAGHAFLTKPPAREP CCCCCCCCCCCCCCC | 34.74 | 26643407 | |
1920 | Acetylation | AGHAFLTKPPAREPA CCCCCCCCCCCCCCC | 51.67 | 23806337 | |
1928 | Phosphorylation | PPAREPASSPSKSSE CCCCCCCCCCCCCCC | 54.20 | 26239621 | |
1929 | Phosphorylation | PAREPASSPSKSSEP CCCCCCCCCCCCCCC | 34.99 | 25521595 | |
1931 | Phosphorylation | REPASSPSKSSEPRS CCCCCCCCCCCCCCC | 47.30 | 26643407 | |
1938 | O-linked_Glycosylation | SKSSEPRSLAPPSSS CCCCCCCCCCCCCCC | 39.33 | 55413925 | |
1943 | Phosphorylation | PRSLAPPSSSHTAIA CCCCCCCCCCCCHHC | 43.33 | 26643407 | |
1944 | O-linked_Glycosylation | RSLAPPSSSHTAIAR CCCCCCCCCCCHHCC | 31.73 | 30059200 | |
1944 | Phosphorylation | RSLAPPSSSHTAIAR CCCCCCCCCCCHHCC | 31.73 | 26643407 | |
1945 | Phosphorylation | SLAPPSSSHTAIART CCCCCCCCCCHHCCC | 29.24 | 26643407 | |
1947 | Phosphorylation | APPSSSHTAIARTPA CCCCCCCCHHCCCCC | 23.00 | 26643407 | |
1952 | Phosphorylation | SHTAIARTPAKNLAP CCCHHCCCCCCCCCC | 20.69 | 26643407 | |
1963 | Phosphorylation | NLAPHHASPDPPAPT CCCCCCCCCCCCCCC | 26.02 | 26824392 | |
1970 | Phosphorylation | SPDPPAPTSASDLHR CCCCCCCCCHHHHCH | 38.74 | 25777480 | |
1971 | Phosphorylation | PDPPAPTSASDLHRE CCCCCCCCHHHHCHH | 25.39 | 25159016 | |
1973 | Phosphorylation | PPAPTSASDLHREKT CCCCCCHHHHCHHHH | 40.24 | 25777480 | |
1979 | Acetylation | ASDLHREKTQSKPFS HHHHCHHHHCCCCCC | 52.39 | 22826441 | |
1982 | Phosphorylation | LHREKTQSKPFSIQE HCHHHHCCCCCCHHE | 47.75 | 25159016 | |
1983 | Acetylation | HREKTQSKPFSIQEL CHHHHCCCCCCHHEE | 40.02 | 23806337 | |
1986 | Phosphorylation | KTQSKPFSIQELELR HHCCCCCCHHEEEHH | 31.71 | 26643407 | |
1994 | Phosphorylation | IQELELRSLGYHSGA HHEEEHHHCCCCCCC | 38.48 | 27087446 | |
1997 | Phosphorylation | LELRSLGYHSGAGYS EEHHHCCCCCCCCCC | 9.71 | 26160508 | |
1999 | Phosphorylation | LRSLGYHSGAGYSPD HHHCCCCCCCCCCCC | 23.12 | 26160508 | |
2003 | Phosphorylation | GYHSGAGYSPDGVEP CCCCCCCCCCCCCCC | 19.25 | 26160508 | |
2004 | Phosphorylation | YHSGAGYSPDGVEPI CCCCCCCCCCCCCCC | 18.65 | 27087446 | |
2012 | Phosphorylation | PDGVEPISPVSSPSL CCCCCCCCCCCCCCC | 29.93 | 27087446 | |
2015 | Phosphorylation | VEPISPVSSPSLTHD CCCCCCCCCCCCCCC | 39.66 | 27087446 | |
2016 | Phosphorylation | EPISPVSSPSLTHDK CCCCCCCCCCCCCCC | 20.81 | 27087446 | |
2018 | Phosphorylation | ISPVSSPSLTHDKGL CCCCCCCCCCCCCCC | 48.09 | 27742792 | |
2020 | Phosphorylation | PVSSPSLTHDKGLSK CCCCCCCCCCCCCCH | 32.16 | 27742792 | |
2035 | Phosphorylation | PLEELEKSHLEGELR HHHHHHHHHHCCCCC | 24.75 | 18846507 | |
2052 | Phosphorylation | QPGPMKLSAEAAHLP CCCCCEEEHHHHCCC | 20.67 | 26643407 | |
2067 | Phosphorylation | HLRPLPESQPSSSPL CCCCCCCCCCCCCCC | 45.51 | 26643407 | |
2070 | Phosphorylation | PLPESQPSSSPLLQT CCCCCCCCCCCCCCC | 35.49 | 26643407 | |
2071 | Phosphorylation | LPESQPSSSPLLQTA CCCCCCCCCCCCCCC | 42.53 | 26643407 | |
2072 | Phosphorylation | PESQPSSSPLLQTAP CCCCCCCCCCCCCCC | 24.73 | 26824392 | |
2075 | Phosphorylation | QPSSSPLLQTAPGIK CCCCCCCCCCCCCCC | 4.89 | - | |
2077 | Phosphorylation | SSSPLLQTAPGIKGH CCCCCCCCCCCCCCH | 34.49 | 26643407 | |
2080 | Phosphorylation | PLLQTAPGIKGHQRV CCCCCCCCCCCHHHH | 31.60 | - | |
2089 | O-linked_Glycosylation | KGHQRVVTLAQHISE CCHHHHHHHHHHHHH | 17.33 | 30059200 | |
2152 | Phosphorylation | HGTPARGSPHSEGGK CCCCCCCCCCCCCCC | 17.56 | 26824392 | |
2155 | Phosphorylation | PARGSPHSEGGKRSP CCCCCCCCCCCCCCC | 41.12 | 26824392 | |
2161 | Phosphorylation | HSEGGKRSPEPSKTS CCCCCCCCCCCCCCC | 36.78 | 26824392 | |
2165 | Phosphorylation | GKRSPEPSKTSVLGS CCCCCCCCCCCCCCC | 47.07 | 25266776 | |
2167 | Phosphorylation | RSPEPSKTSVLGSSE CCCCCCCCCCCCCCC | 28.53 | 25619855 | |
2168 | Phosphorylation | SPEPSKTSVLGSSED CCCCCCCCCCCCCCC | 21.05 | 25619855 | |
2172 | Phosphorylation | SKTSVLGSSEDAIEP CCCCCCCCCCCCCCC | 26.79 | 25619855 | |
2173 | Phosphorylation | KTSVLGSSEDAIEPV CCCCCCCCCCCCCCC | 37.38 | 25619855 | |
2181 | Phosphorylation | EDAIEPVSPPEGMTE CCCCCCCCCCCCCCC | 45.51 | 27087446 | |
2187 | Phosphorylation | VSPPEGMTEPGHARS CCCCCCCCCCCCHHH | 50.30 | 25619855 | |
2213 | Phosphorylation | QGEPRMGSKSPGNTS CCCCCCCCCCCCCCC | 22.18 | 23684622 | |
2215 | Phosphorylation | EPRMGSKSPGNTSQP CCCCCCCCCCCCCCC | 39.47 | 27087446 | |
2219 | Phosphorylation | GSKSPGNTSQPPAFF CCCCCCCCCCCCHHH | 34.35 | 25521595 | |
2220 | Phosphorylation | SKSPGNTSQPPAFFS CCCCCCCCCCCHHHH | 44.69 | 27087446 | |
2227 | Phosphorylation | SQPPAFFSKLTESNS CCCCHHHHHHHHCCC | 21.94 | 25619855 | |
2250 | Phosphorylation | EINKKLNTHNRNEPE HHHHHHHCCCCCCCC | 30.85 | 19737024 | |
2345 | Phosphorylation | ITTADGRSDHALTSP EECCCCCCCCCCCCC | 39.00 | 25777480 | |
2350 | Phosphorylation | GRSDHALTSPGGGGK CCCCCCCCCCCCCCC | 33.39 | 30352176 | |
2351 | Phosphorylation | RSDHALTSPGGGGKA CCCCCCCCCCCCCCC | 23.54 | 25521595 | |
2371 | Phosphorylation | PSSRKAKSPAPGLAS CCCCCCCCCCCCCCC | 31.02 | 26824392 | |
2378 | Phosphorylation | SPAPGLASGDRPPSV CCCCCCCCCCCCCCC | 46.39 | 26060331 | |
2384 | Phosphorylation | ASGDRPPSVSSVHSE CCCCCCCCCCCCCCC | 37.00 | 29472430 | |
2386 | Phosphorylation | GDRPPSVSSVHSEGD CCCCCCCCCCCCCCC | 30.86 | 29472430 | |
2387 | Phosphorylation | DRPPSVSSVHSEGDC CCCCCCCCCCCCCCC | 22.99 | 29472430 | |
2390 | Phosphorylation | PSVSSVHSEGDCNRR CCCCCCCCCCCCCCC | 40.91 | 29472430 | |
2410 | Phosphorylation | RVWEDRPSSAGSTPF CCCCCCCCCCCCCCC | 33.44 | 25168779 | |
2411 | Phosphorylation | VWEDRPSSAGSTPFP CCCCCCCCCCCCCCC | 39.05 | 21082442 | |
2414 | Phosphorylation | DRPSSAGSTPFPYNP CCCCCCCCCCCCCCC | 32.40 | 26239621 | |
2415 | Phosphorylation | RPSSAGSTPFPYNPL CCCCCCCCCCCCCCH | 28.20 | 26239621 | |
2419 | Phosphorylation | AGSTPFPYNPLIMRL CCCCCCCCCCHHHHH | 29.77 | 29899451 | |
2433 | Phosphorylation | LQAGVMASPPPPGLA HCCCCCCCCCCCCCC | 21.61 | 22324799 | |
2469 | Phosphorylation | CSQYETLSDSE---- CCCEEECCCCC---- | 46.65 | 26643407 | |
2471 | Phosphorylation | QYETLSDSE------ CEEECCCCC------ | 41.66 | 26643407 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
1718 | T | Phosphorylation | Kinase | MAPK1 | P63085 | GPS |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NCOR2_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NCOR2_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of NCOR2_MOUSE !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149; SER-152; SER-863;THR-1406 AND SER-1749, AND MASS SPECTROMETRY. | |
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-549; SER-550; SER-938AND SER-2410, AND MASS SPECTROMETRY. |