dbPTM

TM216_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TM216_HUMAN
UniProt AC	Q9P0N5
Protein Name	Transmembrane protein 216
Gene Name	TMEM216
Organism	Homo sapiens (Human).
Sequence Length	145
Subcellular Localization	Membrane Multi-pass membrane protein . Cytoplasm, cytoskeleton, cilium basal body . Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein Description	Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition..
Protein Sequence	MLPRGLKMAPRGKRLSSTPLEILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAMMASYYLLLQTYVLRLEAIMNGILLFFCGSELLLEVLTLAAFSRI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of TM216_HUMAN !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TM216_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TM216_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TM216_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GANP_HUMAN	MCM3AP	physical	16169070
GCP60_HUMAN	ACBD3	physical	26638075
ACSL3_HUMAN	ACSL3	physical	26638075
PLCA_HUMAN	AGPAT1	physical	26638075
GPAT4_HUMAN	AGPAT6	physical	26638075
GPAT3_HUMAN	AGPAT9	physical	26638075
ALG9_HUMAN	ALG9	physical	26638075
ANKL2_HUMAN	ANKLE2	physical	26638075
ANO10_HUMAN	ANO10	physical	26638075
ANO6_HUMAN	ANO6	physical	26638075
ARFG3_HUMAN	ARFGAP3	physical	26638075
RHG01_HUMAN	ARHGAP1	physical	26638075
PRAF3_HUMAN	ARL6IP5	physical	26638075
VAS1_HUMAN	ATP6AP1	physical	26638075
RENR_HUMAN	ATP6AP2	physical	26638075
AUP1_HUMAN	AUP1	physical	26638075
BAP31_HUMAN	BCAP31	physical	26638075
BET1_HUMAN	BET1	physical	26638075
BET1L_HUMAN	BET1L	physical	26638075
CAMLG_HUMAN	CAMLG	physical	26638075
CCD47_HUMAN	CCDC47	physical	26638075
CD99_HUMAN	CD99	physical	26638075
C99L2_HUMAN	CD99L2	physical	26638075
CDCA3_HUMAN	CDCA3	physical	26638075
CDKAL_HUMAN	CDKAL1	physical	26638075
CERS2_HUMAN	CERS2	physical	26638075
CHP1_HUMAN	CHP1	physical	26638075
CISD2_HUMAN	CISD2	physical	26638075
CKAP4_HUMAN	CKAP4	physical	26638075
CLCC1_HUMAN	CLCC1	physical	26638075
CLCN7_HUMAN	CLCN7	physical	26638075
EMC8_HUMAN	EMC8	physical	26638075
CBPD_HUMAN	CPD	physical	26638075
CTND1_HUMAN	CTNND1	physical	26638075
CXAR_HUMAN	CXADR	physical	26638075
CYB5B_HUMAN	CYB5B	physical	26638075
DDRGK_HUMAN	DDRGK1	physical	26638075
DHRS7_HUMAN	DHRS7	physical	26638075
DNJC1_HUMAN	DNAJC1	physical	26638075
EFNB1_HUMAN	EFNB1	physical	26638075
EFNB2_HUMAN	EFNB2	physical	26638075
E2AK3_HUMAN	EIF2AK3	physical	26638075
EMD_HUMAN	EMD	physical	26638075
ESYT1_HUMAN	ESYT1	physical	26638075
F91A1_HUMAN	FAM91A1	physical	26638075
GBA2_HUMAN	GBA2	physical	26638075
GOGA3_HUMAN	GOLGA3	physical	26638075
GOGA5_HUMAN	GOLGA5	physical	26638075
GOT1B_HUMAN	GOLT1B	physical	26638075
GOPC_HUMAN	GOPC	physical	26638075
GORS2_HUMAN	GORASP2	physical	26638075
GOSR1_HUMAN	GOSR1	physical	26638075
GP107_HUMAN	GPR107	physical	26638075
HMOX2_HUMAN	HMOX2	physical	26638075
MPRI_HUMAN	IGF2R	physical	26638075
ITB1_HUMAN	ITGB1	physical	26638075
ITM2C_HUMAN	ITM2C	physical	26638075
JAGN1_HUMAN	JAGN1	physical	26638075
JPH1_HUMAN	JPH1	physical	26638075
EMC1_HUMAN	EMC1	physical	26638075
LNP_HUMAN	KIAA1715	physical	26638075
KTN1_HUMAN	KTN1	physical	26638075
LBR_HUMAN	LBR	physical	26638075
MAN1_HUMAN	LEMD3	physical	26638075
LMAN1_HUMAN	LMAN1	physical	26638075
PCAT1_HUMAN	LPCAT1	physical	26638075
LRC59_HUMAN	LRRC59	physical	26638075
LSR_HUMAN	LSR	physical	26638075
LYSM3_HUMAN	LYSMD3	physical	26638075
MRP_HUMAN	MARCKSL1	physical	26638075
MUC18_HUMAN	MCAM	physical	26638075
MMGT1_HUMAN	MMGT1	physical	26638075
LYRIC_HUMAN	MTDH	physical	26638075
NCOA2_HUMAN	NCOA2	physical	26638075
NSDHL_HUMAN	NSDHL	physical	26638075
NU155_HUMAN	NUP155	physical	26638075
NUP53_HUMAN	NUP35	physical	26638075
OCLN_HUMAN	OCLN	physical	26638075
OSBP1_HUMAN	OSBP	physical	26638075
OSBL8_HUMAN	OSBPL8	physical	26638075
PHLP_HUMAN	PDCL	physical	26638075
PDXD1_HUMAN	PDXDC1	physical	26638075
PDZD8_HUMAN	PDZD8	physical	26638075
PGRC2_HUMAN	PGRMC2	physical	26638075
NCPR_HUMAN	POR	physical	26638075
PREB_HUMAN	PREB	physical	26638075
PTN1_HUMAN	PTPN1	physical	26638075
NECT2_HUMAN	PVRL2	physical	26638075
RAB7A_HUMAN	RAB7A	physical	26638075
RABL3_HUMAN	RABL3	physical	26638075
RELL1_HUMAN	RELL1	physical	26638075
RER1_HUMAN	RER1	physical	26638075
RHBD2_HUMAN	RHBDD2	physical	26638075
ROR2_HUMAN	ROR2	physical	26638075
RTN4_HUMAN	RTN4	physical	26638075
SCAM1_HUMAN	SCAMP1	physical	26638075
SCFD1_HUMAN	SCFD1	physical	26638075
PACE1_HUMAN	SCYL3	physical	26638075
SC11A_HUMAN	SEC11A	physical	26638075
SC22B_HUMAN	SEC22B	physical	26638075
SC24B_HUMAN	SEC24B	physical	26638075
SEC63_HUMAN	SEC63	physical	26638075
SEM6A_HUMAN	SEMA6A	physical	26638075
SFT2C_HUMAN	SFT2D3	physical	26638075
SGPL1_HUMAN	SGPL1	physical	26638075
S12A2_HUMAN	SLC12A2	physical	26638075
S12A4_HUMAN	SLC12A4	physical	26638075
AAAT_HUMAN	SLC1A5	physical	26638075
S20A2_HUMAN	SLC20A2	physical	26638075
ZNT5_HUMAN	SLC30A5	physical	26638075
ZNT6_HUMAN	SLC30A6	physical	26638075
ACATN_HUMAN	SLC33A1	physical	26638075
S38A1_HUMAN	SLC38A1	physical	26638075
S38A2_HUMAN	SLC38A2	physical	26638075
S39AA_HUMAN	SLC39A10	physical	26638075
S39A6_HUMAN	SLC39A6	physical	26638075
S39A7_HUMAN	SLC39A7	physical	26638075
4F2_HUMAN	SLC3A2	physical	26638075
S4A7_HUMAN	SLC4A7	physical	26638075
S6A15_HUMAN	SLC6A15	physical	26638075
SC6A8_HUMAN	SLC6A8	physical	26638075
SC6A9_HUMAN	SLC6A9	physical	26638075
LAT1_HUMAN	SLC7A5	physical	26638075
NSMA3_HUMAN	SMPD4	physical	26638075
SNP23_HUMAN	SNAP23	physical	26638075
SPCS2_HUMAN	SPCS2	physical	26638075
SRPRA_HUMAN	SRPR	physical	26638075
STAM1_HUMAN	STAM	physical	26638075
STEA3_HUMAN	STEAP3	physical	26638075
STIM1_HUMAN	STIM1	physical	26638075
STX10_HUMAN	STX10	physical	26638075
STX12_HUMAN	STX12	physical	26638075
STX5_HUMAN	STX5	physical	26638075
STX6_HUMAN	STX6	physical	26638075
STX7_HUMAN	STX7	physical	26638075
STX8_HUMAN	STX8	physical	26638075
TX264_HUMAN	TEX264	physical	26638075
TFR1_HUMAN	TFRC	physical	26638075
EMC3_HUMAN	EMC3	physical	26638075
TM115_HUMAN	TMEM115	physical	26638075
TM199_HUMAN	TMEM199	physical	26638075
TM209_HUMAN	TMEM209	physical	26638075
TM214_HUMAN	TMEM214	physical	26638075
NDC1_HUMAN	NDC1	physical	26638075
TMM51_HUMAN	TMEM51	physical	26638075
TM87A_HUMAN	TMEM87A	physical	26638075
TMEM9_HUMAN	TMEM9	physical	26638075
LAP2A_HUMAN	TMPO	physical	26638075
LAP2B_HUMAN	TMPO	physical	26638075
TMX1_HUMAN	TMX1	physical	26638075
TMX4_HUMAN	TMX4	physical	26638075
TOIP1_HUMAN	TOR1AIP1	physical	26638075
TRI13_HUMAN	TRIM13	physical	26638075
EMC2_HUMAN	EMC2	physical	26638075
UB2J1_HUMAN	UBE2J1	physical	26638075
UBXN4_HUMAN	UBXN4	physical	26638075
USE1_HUMAN	USE1	physical	26638075
VAMP2_HUMAN	VAMP2	physical	26638075
VAMP3_HUMAN	VAMP3	physical	26638075
VANG1_HUMAN	VANGL1	physical	26638075
VAPA_HUMAN	VAPA	physical	26638075
VAPB_HUMAN	VAPB	physical	26638075
VEZA_HUMAN	VEZT	physical	26638075
VMA21_HUMAN	VMA21	physical	26638075
VMP1_HUMAN	VMP1	physical	26638075
VRK2_HUMAN	VRK2	physical	26638075
WDR11_HUMAN	WDR11	physical	26638075
WDR41_HUMAN	WDR41	physical	26638075
YKT6_HUMAN	YKT6	physical	26638075
ABCE1_HUMAN	ABCE1	physical	26638075
AL3A2_HUMAN	ALDH3A2	physical	26638075
APBB1_HUMAN	APBB1	physical	26638075
A4_HUMAN	APP	physical	26638075
COPD_HUMAN	ARCN1	physical	26638075
ARFG2_HUMAN	ARFGAP2	physical	26638075
ARFP1_HUMAN	ARFIP1	physical	26638075
VPP1_HUMAN	ATP6V0A1	physical	26638075
VATF_HUMAN	ATP6V1F	physical	26638075
BSDC1_HUMAN	BSDC1	physical	26638075
EMC7_HUMAN	EMC7	physical	26638075
THEM6_HUMAN	THEM6	physical	26638075
CAV1_HUMAN	CAV1	physical	26638075
CC115_HUMAN	CCDC115	physical	26638075
EPN4_HUMAN	CLINT1	physical	26638075
COPB_HUMAN	COPB1	physical	26638075
COPG1_HUMAN	COPG1	physical	26638075
DSC2_HUMAN	DSC2	physical	26638075
DSG2_HUMAN	DSG2	physical	26638075
RCAS1_HUMAN	EBAG9	physical	26638075
EPHA2_HUMAN	EPHA2	physical	26638075
EPHA7_HUMAN	EPHA7	physical	26638075
JAM1_HUMAN	F11R	physical	26638075
RETR1_HUMAN	FAM134B	physical	26638075
FKBP8_HUMAN	FKBP8	physical	26638075
FZD6_HUMAN	FZD6	physical	26638075
GORAB_HUMAN	GORAB	physical	26638075
GP108_HUMAN	GPR108	physical	26638075
IRS4_HUMAN	IRS4	physical	26638075
JAG2_HUMAN	JAG2	physical	26638075
K319L_HUMAN	KIAA0319L	physical	26638075
PALD_HUMAN	PALD1	physical	26638075
LCAP_HUMAN	LNPEP	physical	26638075
LRBA_HUMAN	LRBA	physical	26638075
LSG1_HUMAN	LSG1	physical	26638075
MALD2_HUMAN	MARVELD2	physical	26638075
M21D2_HUMAN	MB21D2	physical	26638075
MSPD2_HUMAN	MOSPD2	physical	26638075
OSB11_HUMAN	OSBPL11	physical	26638075
PMYT1_HUMAN	PKMYT1	physical	26638075
PLD3_HUMAN	PLD3	physical	26638075
PTN2_HUMAN	PTPN2	physical	26638075
SCRB1_HUMAN	SCARB1	physical	26638075
SC23B_HUMAN	SEC23B	physical	26638075
S23IP_HUMAN	SEC23IP	physical	26638075
SENP2_HUMAN	SENP2	physical	26638075
S19A1_HUMAN	SLC19A1	physical	26638075
S39AE_HUMAN	SLC39A14	physical	26638075
SC6A6_HUMAN	SLC6A6	physical	26638075
SOAT1_HUMAN	SOAT1	physical	26638075
SPCS3_HUMAN	SPCS3	physical	26638075
SRPRB_HUMAN	SRPRB	physical	26638075
SSRA_HUMAN	SSR1	physical	26638075
STAM2_HUMAN	STAM2	physical	26638075
STT3B_HUMAN	STT3B	physical	26638075
STX18_HUMAN	STX18	physical	26638075
SUN1_HUMAN	SUN1	physical	26638075
SYAP1_HUMAN	SYAP1	physical	26638075
TB22B_HUMAN	TBC1D22B	physical	26638075
TEX2_HUMAN	TEX2	physical	26638075
TM109_HUMAN	TMEM109	physical	26638075
MACOI_HUMAN	TMEM57	physical	26638075
TMF1_HUMAN	TMF1	physical	26638075
TOIP2_HUMAN	TOR1AIP2	physical	26638075
IFG15_HUMAN	TOR1AIP2	physical	26638075
UB2G2_HUMAN	UBE2G2	physical	26638075
UBIA1_HUMAN	UBIAD1	physical	26638075
CGT_HUMAN	UGT8	physical	26638075
UNC5B_HUMAN	UNC5B	physical	26638075
VANG2_HUMAN	VANGL2	physical	26638075
VAT1_HUMAN	VAT1	physical	26638075
VKORL_HUMAN	VKORC1L1	physical	26638075
WDR6_HUMAN	WDR6	physical	26638075
AGRL2_HUMAN	LPHN2	physical	26638075

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TM216_HUMAN

Related Literatures of Post-Translational Modification