GP108_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GP108_HUMAN
• UniProt AC: Q9NPR9
• Protein Name: Protein GPR108
• Gene Name: GPR108
• Organism: Homo sapiens (Human).
• Sequence Length: 543
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MAVSERRGLGRGSPAEWGQRLLLVLLLGGCSGRIHQLALTGEKRADIQLNSFGFYTNGSLEVELSVLRLGLREAEEKSLLVGFSLSRVRSGRVRSYSTRDFQDCPLQKNSSSFLVLFLINTKDLQVQVRKYGEQKTLFIFPGLLPEAPSKPGLPKPQATVPRKVDGGGTSAASKPKSTPAVIQGPSGKDKDLVLGLSHLNNSYNFSFHVVIGSQAEEGQYSLNFHNCNNSVPGKEHPFDITVMIREKNPDGFLSAAEMPLFKLYMVMSACFLAAGIFWVSILCRNTYSVFKIHWLMAALAFTKSISLLFHSINYYFINSQGHPIEGLAVMYYIAHLLKGALLFITIALIGSGWAFIKYVLSDKEKKVFGIVIPMQVLANVAYIIIESREEGASDYVLWKEILFLVDLICCGAILFPVVWSIRHLQDASGTDGKVAVNLAKLKLFRHYYVMVICYVYFTRIIAILLQVAVPFQWQWLYQLLVEGSTLAFFVLTGYKFQPTGNNPYLQLPQEDEEDVQMEQVMTDSGFREGLSKVNKTASGRELL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	N-linked_Glycosylation	NSFGFYTNGSLEVEL EEEEEECCCCEEEEE	27.03	UniProtKB CARBOHYD
65	Phosphorylation	GSLEVELSVLRLGLR CCEEEEEEHHHHCCC	12.95	24719451
109	N-linked_Glycosylation	QDCPLQKNSSSFLVL CCCCCCCCCCCEEEE	33.88	UniProtKB CARBOHYD
159	Phosphorylation	GLPKPQATVPRKVDG CCCCCCCCCCEEECC	26.29	24719451
169	Phosphorylation	RKVDGGGTSAASKPK EEECCCCCCCCCCCC	20.61	24114839
169	O-linked_Glycosylation	RKVDGGGTSAASKPK EEECCCCCCCCCCCC	20.61	OGP
170	O-linked_Glycosylation	KVDGGGTSAASKPKS EECCCCCCCCCCCCC	25.72	30620550
173	Phosphorylation	GGGTSAASKPKSTPA CCCCCCCCCCCCCCC	49.56	24114839
173	O-linked_Glycosylation	GGGTSAASKPKSTPA CCCCCCCCCCCCCCC	49.56	30620550
177	O-linked_Glycosylation	SAASKPKSTPAVIQG CCCCCCCCCCCEEEC	48.42	55833219
178	O-linked_Glycosylation	AASKPKSTPAVIQGP CCCCCCCCCCEEECC	22.76	55833223
200	N-linked_Glycosylation	VLGLSHLNNSYNFSF EEEEECCCCCCEEEE	29.94	UniProtKB CARBOHYD
204	N-linked_Glycosylation	SHLNNSYNFSFHVVI ECCCCCCEEEEEEEE	26.38	UniProtKB CARBOHYD
228	N-linked_Glycosylation	SLNFHNCNNSVPGKE EEEEECCCCCCCCCC	49.48	UniProtKB CARBOHYD
241	Phosphorylation	KEHPFDITVMIREKN CCCCCEEEEEEEECC	13.08	27251275
302	Phosphorylation	LMAALAFTKSISLLF HHHHHHHHHHHHHHH	20.48	-
433	Ubiquitination	DASGTDGKVAVNLAK HCCCCCCHHHHHHHH	29.81	2190698
532	Ubiquitination	GFREGLSKVNKTASG HHHHHHHHCCCCCCC	55.67	-
534	N-linked_Glycosylation	REGLSKVNKTASGRE HHHHHHCCCCCCCCC	39.43	UniProtKB CARBOHYD
535	Ubiquitination	EGLSKVNKTASGREL HHHHHCCCCCCCCCC	48.75	-
536	Phosphorylation	GLSKVNKTASGRELL HHHHCCCCCCCCCCC	22.35	23186163
538	Phosphorylation	SKVNKTASGRELL-- HHCCCCCCCCCCC--	43.55	28857561

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GP108_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GP108_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GP108_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GP108_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.