LYSM3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LYSM3_HUMAN
• UniProt AC: Q7Z3D4
• Protein Name: LysM and putative peptidoglycan-binding domain-containing protein 3
• Gene Name: LYSMD3
• Organism: Homo sapiens (Human).
• Sequence Length: 306
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MAGRHQNRSFPLPGVQSSGQVHAFGNCSDSDILEEDAEVYELRSRGKEKVRRSTSRDRLDDIIVLTKDIQEGDTLNAIALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKKFSSLTETLCPPKGRQTSRHSSVQYSSEQQEILPANDSLAYSDSAGSFLKEVDRDIEQIVKCTDNKRENLNEVVSALTAQQMRFEPDNKNTQRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVDSSHLHSKITPPSQQREMENGIVPTKGIHFSQQDDHKLYSQDSQSPAAQQET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	N-linked_Glycosylation	-MAGRHQNRSFPLPG -CCCCCCCCCCCCCC	35.12	UniProtKB CARBOHYD
9	Phosphorylation	AGRHQNRSFPLPGVQ CCCCCCCCCCCCCCC	38.47	26074081
17	Phosphorylation	FPLPGVQSSGQVHAF CCCCCCCCCCCEEEE	33.75	26074081
18	Phosphorylation	PLPGVQSSGQVHAFG CCCCCCCCCCEEEEC	19.02	26074081
28	Phosphorylation	VHAFGNCSDSDILEE EEEECCCCCCHHHHC	44.12	26074081
30	Phosphorylation	AFGNCSDSDILEEDA EECCCCCCHHHHCCH	15.40	26074081
40	Phosphorylation	LEEDAEVYELRSRGK HHCCHHHHHHHHCCH	10.76	27642862
53 (in isoform 3)	Phosphorylation	-	21.85	21406692
53	Phosphorylation	GKEKVRRSTSRDRLD CHHHHHHCCCHHHCC	21.85	23401153
54	Phosphorylation	KEKVRRSTSRDRLDD HHHHHHCCCHHHCCC	26.43	30266825
55	Phosphorylation	EKVRRSTSRDRLDDI HHHHHCCCHHHCCCE	33.17	30266825
66	Phosphorylation	LDDIIVLTKDIQEGD CCCEEEEECCCCCCC	18.77	23403867
108	2-Hydroxyisobutyrylation	FFALRSIKIPVKKFS CHHHHCCCCCHHHCC	42.05	-
115	Phosphorylation	KIPVKKFSSLTETLC CCCHHHCCCCCCCCC	33.06	23898821
116	Phosphorylation	IPVKKFSSLTETLCP CCHHHCCCCCCCCCC	42.30	23898821
130	Phosphorylation	PPKGRQTSRHSSVQY CCCCCCCCCCCCCCC	21.47	-
133	Phosphorylation	GRQTSRHSSVQYSSE CCCCCCCCCCCCCHH	30.97	26699800
134	Phosphorylation	RQTSRHSSVQYSSEQ CCCCCCCCCCCCHHH	13.71	26699800
137	Phosphorylation	SRHSSVQYSSEQQEI CCCCCCCCCHHHCCE	16.41	26699800
138	Phosphorylation	RHSSVQYSSEQQEIL CCCCCCCCHHHCCEE	15.42	27080861
139	Phosphorylation	HSSVQYSSEQQEILP CCCCCCCHHHCCEEC	34.19	27080861
153	Phosphorylation	PANDSLAYSDSAGSF CCCCCCEECCCCHHH	20.50	27642862
159	Phosphorylation	AYSDSAGSFLKEVDR EECCCCHHHHHHHCC	27.42	24719451
162	Ubiquitination	DSAGSFLKEVDRDIE CCCHHHHHHHCCCHH	54.39	-
201	Ubiquitination	MRFEPDNKNTQRKDP HCCCCCCCCCCCCCC	69.61	-
249	O-linked_Glycosylation	ILAKVDVSHHSTVDS HHHCCCCCCCCCCCC	15.83	OGP
252	O-linked_Glycosylation	KVDVSHHSTVDSSHL CCCCCCCCCCCCHHH	25.38	55821279
253	O-linked_Glycosylation	VDVSHHSTVDSSHLH CCCCCCCCCCCHHHC	24.79	55821285
256	O-linked_Glycosylation	SHHSTVDSSHLHSKI CCCCCCCCHHHCCCC	18.47	OGP
257	O-linked_Glycosylation	HHSTVDSSHLHSKIT CCCCCCCHHHCCCCC	26.13	55821291
261	O-linked_Glycosylation	VDSSHLHSKITPPSQ CCCHHHCCCCCCHHH	31.92	55821297
264	Phosphorylation	SHLHSKITPPSQQRE HHHCCCCCCHHHHHH	32.65	24719451
267	Phosphorylation	HSKITPPSQQREMEN CCCCCCHHHHHHHHC	39.90	24719451
279	O-linked_Glycosylation	MENGIVPTKGIHFSQ HHCCCCCCCCCCCCC	30.89	55821443
285	O-linked_Glycosylation	PTKGIHFSQQDDHKL CCCCCCCCCCCCCCC	16.87	OGP
299	Phosphorylation	LYSQDSQSPAAQQET CCCCCCCCHHHHHCC	22.06	25627689

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LYSM3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LYSM3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LYSM3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of LYSM3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.