BSDC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BSDC1_HUMAN
• UniProt AC: Q9NW68
• Protein Name: BSD domain-containing protein 1
• Gene Name: BSDC1
• Organism: Homo sapiens (Human).
• Sequence Length: 430
• Protein Sequence: MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLATEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	WRSWLQQSYQAVKEK HHHHHHHHHHHHHHH	13.27	28796482
18	Phosphorylation	RSWLQQSYQAVKEKS HHHHHHHHHHHHHHH	8.99	28796482
18 (in isoform 3)	Phosphorylation	-	8.99	27642862
24	Ubiquitination	SYQAVKEKSSEALEF HHHHHHHHHHHHHHH	54.27	29967540
25	Phosphorylation	YQAVKEKSSEALEFM HHHHHHHHHHHHHHH	34.21	-
33	Ubiquitination	SEALEFMKRDLTEFT HHHHHHHHHCHHHHH	48.35	32015554
37	Phosphorylation	EFMKRDLTEFTQVVQ HHHHHCHHHHHHHHC	33.08	-
40	Phosphorylation	KRDLTEFTQVVQHDT HHCHHHHHHHHCCCH	17.77	-
73	Ubiquitination	GSSGATEKMKKGLSD CCCCHHHHHHHHHHH	52.22	-
75	Ubiquitination	SGATEKMKKGLSDFL CCHHHHHHHHHHHHH	55.55	-
76	Ubiquitination	GATEKMKKGLSDFLG CHHHHHHHHHHHHHH	62.68	-
79	Phosphorylation	EKMKKGLSDFLGVIS HHHHHHHHHHHHHHC	34.68	27499020
80	Ubiquitination	KMKKGLSDFLGVISD HHHHHHHHHHHHHCC	48.08	32015554
81 (in isoform 6)	Phosphorylation	-	6.01	22210691
82 (in isoform 6)	Phosphorylation	-	6.85	22210691
89 (in isoform 6)	Phosphorylation	-	12.97	22210691
92	Phosphorylation	ISDTFAPSPDKTIDC HCCCCCCCCCCCCCC	42.15	25159151
96 (in isoform 6)	Phosphorylation	-	29.45	22210691
103	Phosphorylation	TIDCDVITLMGTPSG CCCCEEEEECCCCCC	15.56	27251275
107	Phosphorylation	DVITLMGTPSGTAEP EEEEECCCCCCCCCC	10.58	21815630
109 (in isoform 7)	Phosphorylation	-	48.92	27251275
109	Phosphorylation	ITLMGTPSGTAEPYD EEECCCCCCCCCCCC	48.92	25159151
111	Phosphorylation	LMGTPSGTAEPYDGT ECCCCCCCCCCCCCC	31.99	27251275
119	Ubiquitination	AEPYDGTKARLYSLQ CCCCCCCEEEEEEEC	36.72	32015554
124 (in isoform 7)	Phosphorylation	-	25.23	27251275
131	Phosphorylation	SLQSDPATYCNEPDG EECCCCCCCCCCCCC	33.71	30576142
132	Phosphorylation	LQSDPATYCNEPDGP ECCCCCCCCCCCCCC	8.72	30576142
148	Phosphorylation	ELFDAWLSQFCLEEK HHHHHHHHHHHHHHH	15.54	30576142
166	Phosphorylation	ISELLVGSPSIRALY HHHHHCCCHHHHHHH	14.16	25159151
168	Phosphorylation	ELLVGSPSIRALYTK HHHCCCHHHHHHHHC	26.80	22199227
175	Ubiquitination	SIRALYTKMVPAAVS HHHHHHHCHHCCCCC	25.09	32015554
183 (in isoform 7)	Phosphorylation	-	25.42	24719451
192	Ubiquitination	EFWHRYFYKVHQLEQ HHHHHHHHHHHHHHH	11.81	32015554
214	Phosphorylation	LKQRAEQSISEEPGW HHHHHHHHHCCCCCC	21.42	26657352
216	Phosphorylation	QRAEQSISEEPGWEE HHHHHHHCCCCCCHH	40.95	22199227
231 (in isoform 7)	Phosphorylation	-	2.49	24719451
232	Phosphorylation	EEELMGISPISPKEA HHHHHCCCCCCHHHC	15.51	26657352
233 (in isoform 7)	Phosphorylation	-	29.20	27251275
235	Phosphorylation	LMGISPISPKEAKVP HHCCCCCCHHHCCCC	33.05	25106551
247	Phosphorylation	KVPVAKISTFPEGEP CCCEEEEECCCCCCC	24.24	26074081
248	Phosphorylation	VPVAKISTFPEGEPG CCEEEEECCCCCCCC	46.83	26074081
252 (in isoform 7)	Phosphorylation	-	46.79	24719451
258	Phosphorylation	EGEPGPQSPCEENLV CCCCCCCCCCCCCCC	34.35	27251275
266	Phosphorylation	PCEENLVTSVEPPAE CCCCCCCCEECCCCC	30.16	28348404
267	Phosphorylation	CEENLVTSVEPPAEV CCCCCCCEECCCCCC	19.60	28348404
275	Phosphorylation	VEPPAEVTPSESSES ECCCCCCCCCCCCCC	16.77	28348404
277	Phosphorylation	PPAEVTPSESSESIS CCCCCCCCCCCCCEE	40.52	28348404
279	Phosphorylation	AEVTPSESSESISLV CCCCCCCCCCCEEEE	43.68	28348404
280	Phosphorylation	EVTPSESSESISLVT CCCCCCCCCCEEEEE	31.17	28348404
282	Phosphorylation	TPSESSESISLVTQI CCCCCCCCEEEEEEE	21.30	28348404
284 (in isoform 7)	Phosphorylation	-	26.51	27251275
284	Phosphorylation	SESSESISLVTQIAN CCCCCCEEEEEEECC	26.51	28348404
287	Phosphorylation	SESISLVTQIANPAT CCCEEEEEEECCCCC	21.39	28348404
293	Phosphorylation	VTQIANPATAPEARV EEEECCCCCCCCCCC	19.05	32142685
306	Phosphorylation	RVLPKDLSQKLLEAS CCCCHHHHHHHHHHH	35.09	24719451
313	Phosphorylation	SQKLLEASLEEQGLA HHHHHHHHHHHCCCE	27.26	25159151
323 (in isoform 7)	Phosphorylation	-	6.32	24719451
326	Phosphorylation	LAVDVGETGPSPPIH CEEECCCCCCCCCCC	48.76	28348404
329	Phosphorylation	DVGETGPSPPIHSKP ECCCCCCCCCCCCCC	44.65	25159151
330 (in isoform 7)	Phosphorylation	-	34.69	27251275
332	Phosphorylation	ETGPSPPIHSKPLTP CCCCCCCCCCCCCCC	6.95	32142685
334	Phosphorylation	GPSPPIHSKPLTPAG CCCCCCCCCCCCCCC	36.37	24719451
335 (in isoform 4)	Phosphorylation	-	29.86	22210691
336 (in isoform 4)	Phosphorylation	-	44.47	22210691
338	Phosphorylation	PIHSKPLTPAGHTGG CCCCCCCCCCCCCCC	21.44	25159151
343	Phosphorylation	PLTPAGHTGGPEPRP CCCCCCCCCCCCCCC	42.80	25159151
343 (in isoform 4)	Phosphorylation	-	42.80	22210691
350 (in isoform 4)	Phosphorylation	-	37.30	22210691
356	Phosphorylation	RPPARVETLREEAPT CCCCCHHHHHHHCCC	28.40	23312004
366	Methylation	EEAPTDLRVFELNSD HHCCCCEEEEEEECC	33.61	-
372	Phosphorylation	LRVFELNSDSGKSTP EEEEEEECCCCCCCC	45.86	21815630
374	Phosphorylation	VFELNSDSGKSTPSN EEEEECCCCCCCCCC	48.19	21815630
377	Phosphorylation	LNSDSGKSTPSNNGK EECCCCCCCCCCCCC	49.42	20363803
378	Phosphorylation	NSDSGKSTPSNNGKK ECCCCCCCCCCCCCC	33.93	22115753
380	Phosphorylation	DSGKSTPSNNGKKGS CCCCCCCCCCCCCCC	42.91	20363803
387	Phosphorylation	SNNGKKGSSTDISED CCCCCCCCCCCCCCH	38.66	28355574
388	Phosphorylation	NNGKKGSSTDISEDW CCCCCCCCCCCCCHH	38.47	25159151
389 (in isoform 7)	Phosphorylation	-	38.76	24719451
389	Phosphorylation	NGKKGSSTDISEDWE CCCCCCCCCCCCHHH	38.76	25159151
392	Phosphorylation	KGSSTDISEDWEKDF CCCCCCCCCHHHHHC	32.11	25159151
404 (in isoform 3)	Phosphorylation	-	39.65	21406692
404	Phosphorylation	KDFDLDMTEEEVQMA HHCCCCCCHHHHHHH	39.65	22199227
404 (in isoform 7)	Phosphorylation	-	39.65	24719451
405 (in isoform 7)	Phosphorylation	-	45.59	27251275
405	Phosphorylation	DFDLDMTEEEVQMAL HCCCCCCHHHHHHHH	45.59	32142685
409 (in isoform 7)	Phosphorylation	-	18.08	27251275
413	Phosphorylation	EEVQMALSKVDASGE HHHHHHHHCCCCCCC	22.54	28348404
418	Phosphorylation	ALSKVDASGELEDVE HHHCCCCCCCCCCCC	28.47	20068231
421 (in isoform 7)	Phosphorylation	-	8.53	27251275
435 (in isoform 7)	Phosphorylation	-		27251275
456 (in isoform 3)	Phosphorylation	-		22210691
457 (in isoform 3)	Phosphorylation	-		22210691
464 (in isoform 3)	Phosphorylation	-		22210691
471 (in isoform 3)	Phosphorylation	-		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BSDC1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BSDC1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BSDC1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLC1_HUMAN	KLC1	physical	21915095

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.