| UniProt ID | VHT1_YEAST | |
|---|---|---|
| UniProt AC | P53241 | |
| Protein Name | Vitamin H transporter | |
| Gene Name | VHT1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 593 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein. |
|
| Protein Description | Involved in uptake of biotin with the concomitant entry of protons.. | |
| Protein Sequence | MTISNKSWRSYFPHLRKLPEDDQYLYSDDTNSSIIAEEELHHSVDKSSKTDVTAETTAVEPHPHNLRHDLPYEVRDEAGRKWWKYFDEFEYRVNKEYKKSRKWYEFLYPNHTTQTKAERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGSYTLWLKSNTKYSIAQVNNLSVIPACLGFAYVIFCAFGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTYFSVAASPCLWSFINDFLRFDPQVKAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIYGLWTFVVLFFYKRNEKKHALGNGIILYDSNKGEELPEFVKKNMEERDGYYYLKRSS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 24 | Phosphorylation | KLPEDDQYLYSDDTN CCCCCCCCCCCCCCC | 18.01 | 19779198 | |
| 26 | Phosphorylation | PEDDQYLYSDDTNSS CCCCCCCCCCCCCCC | 12.72 | 22369663 | |
| 27 | Phosphorylation | EDDQYLYSDDTNSSI CCCCCCCCCCCCCCE | 26.81 | 20377248 | |
| 30 | Phosphorylation | QYLYSDDTNSSIIAE CCCCCCCCCCCEEEH | 41.83 | 20377248 | |
| 32 | Phosphorylation | LYSDDTNSSIIAEEE CCCCCCCCCEEEHHH | 25.63 | 22369663 | |
| 33 | Phosphorylation | YSDDTNSSIIAEEEL CCCCCCCCEEEHHHH | 21.78 | 22369663 | |
| 43 | Phosphorylation | AEEELHHSVDKSSKT EHHHHHHCCCCCCCC | 22.66 | 22369663 | |
| 46 | Ubiquitination | ELHHSVDKSSKTDVT HHHHCCCCCCCCCCC | 55.24 | 24961812 | |
| 47 | Phosphorylation | LHHSVDKSSKTDVTA HHHCCCCCCCCCCCE | 32.38 | 19779198 | |
| 49 | Ubiquitination | HSVDKSSKTDVTAET HCCCCCCCCCCCEEE | 56.70 | 24961812 | |
| 50 | Phosphorylation | SVDKSSKTDVTAETT CCCCCCCCCCCEEEE | 37.34 | 19779198 | |
| 53 | Phosphorylation | KSSKTDVTAETTAVE CCCCCCCCEEEECCC | 22.91 | 28889911 | |
| 56 | Phosphorylation | KTDVTAETTAVEPHP CCCCCEEEECCCCCC | 20.00 | 28889911 | |
| 269 | Phosphorylation | QQLGSVTSGLLQSRI CCCCHHHHHHHHHHH | 25.86 | 19779198 | |
| 279 | Phosphorylation | LQSRIFKSLNGVHGL HHHHHHHHHCCCCCC | 19.13 | 19779198 | |
| 342 | Ubiquitination | RNKRNQIKDGVDKSK HHHHHHCCCCCCHHH | 38.37 | 23749301 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VHT1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VHT1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VHT1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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