| UniProt ID | SPO7_YEAST | |
|---|---|---|
| UniProt AC | P18410 | |
| Protein Name | Sporulation-specific protein SPO7 | |
| Gene Name | SPO7 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 259 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . Nucleus membrane Multi-pass membrane protein . |
|
| Protein Description | Regulatory component of the NEM1-SPO7 complex which acts as a phosphatase and dephosphorylates the phosphatidic acid phosphohydrolase PAH1. [PubMed: 15889145 Essential for the formation of a spherical nucleus and meiotic division] | |
| Protein Sequence | MEPESIGDVGNHAQDDSASIVSGPRRRSTSKTSSAKNIRNSSNISPASMIFRNLLILEDDLRRQAHEQKILKWQFTLFLASMAGVGAFTFYELYFTSDYVKGLHRVILQFTLSFISITVVLFHISGQYRRTIVIPRRFFTSTNKGIRQFNVKLVKVQSTWDEKYTDSVRFVSRTIAYCNIYCLKKFLWLKDDNAIVKFWKSVTIQSQPRIGAVDVKLVLNPRAFSAEIREGWEIYRDEFWAREGARRRKQAHELRPKSE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MEPESIGDVGNH ---CCCCCCCCCCCC | 42.46 | 30377154 | |
| 17 | Phosphorylation | GNHAQDDSASIVSGP CCCCCCCCCCCCCCC | 32.00 | 23749301 | |
| 19 | Phosphorylation | HAQDDSASIVSGPRR CCCCCCCCCCCCCCC | 27.72 | 23749301 | |
| 22 | Phosphorylation | DDSASIVSGPRRRST CCCCCCCCCCCCCCC | 41.22 | 23749301 | |
| 28 | Phosphorylation | VSGPRRRSTSKTSSA CCCCCCCCCCCCCCC | 34.91 | 26447709 | |
| 29 | Phosphorylation | SGPRRRSTSKTSSAK CCCCCCCCCCCCCCH | 32.22 | 26447709 | |
| 30 | Phosphorylation | GPRRRSTSKTSSAKN CCCCCCCCCCCCCHH | 34.87 | 26447709 | |
| 32 | Phosphorylation | RRRSTSKTSSAKNIR CCCCCCCCCCCHHHH | 27.90 | 26447709 | |
| 33 | Phosphorylation | RRSTSKTSSAKNIRN CCCCCCCCCCHHHHC | 31.84 | 26447709 | |
| 34 | Phosphorylation | RSTSKTSSAKNIRNS CCCCCCCCCHHHHCC | 48.79 | 26447709 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SPO7_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SPO7_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SPO7_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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