| UniProt ID | STB5L_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y2K9 | |
| Protein Name | Syntaxin-binding protein 5-like | |
| Gene Name | STXBP5L | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1186 | |
| Subcellular Localization |
Cytoplasm . Cell membrane Peripheral membrane protein . Membrane Peripheral membrane protein . Cytoplasmic, and associated with vesicular membranes and the plasma membrane. |
|
| Protein Description | May play a role in vesicle trafficking and exocytosis.. | |
| Protein Sequence | MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGRKSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASAITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MKKFNFRK -------CCCCCHHH | 45.28 | 22814378 | |
| 171 | Phosphorylation | PFQSKWLYVGTERGN CCCCEEEEEEECCCC | 8.84 | - | |
| 232 | Phosphorylation | LIGYENGTVVFWDLK EEEEECCEEEEEECC | 25.69 | 27251275 | |
| 248 | Phosphorylation | KRAELRVYYDEAIHS CCEEEEEECHHHHHC | 9.96 | 26657352 | |
| 268 | Phosphorylation | EGKQFMCSHSDGSLT CCCEEEEECCCCCEE | 17.78 | 26657352 | |
| 270 | Phosphorylation | KQFMCSHSDGSLTLW CEEEEECCCCCEEEE | 27.63 | 24043423 | |
| 273 | Phosphorylation | MCSHSDGSLTLWNLK EEECCCCCEEEEECC | 24.15 | 24043423 | |
| 275 | Phosphorylation | SHSDGSLTLWNLKSP ECCCCCEEEEECCCC | 31.27 | 24043423 | |
| 472 | Phosphorylation | ITGHADGSIKFWDAS EECCCCCCEEEEEHH | 24.13 | - | |
| 544 | Phosphorylation | YVIIYKFSRHEITTE EEEEEEECCCEEEEE | 28.68 | 24719451 | |
| 568 | Phosphorylation | YDVEDIITPEPETSP CCHHHCCCCCCCCCC | 23.18 | - | |
| 574 | Phosphorylation | ITPEPETSPPFPDLS CCCCCCCCCCCCCHH | 28.99 | - | |
| 589 | Phosphorylation | AQLPSSRSLSGSTNT HCCCCCCCCCCCCCC | 28.92 | 28985074 | |
| 591 | Phosphorylation | LPSSRSLSGSTNTVA CCCCCCCCCCCCCCC | 31.76 | 27732954 | |
| 593 | Phosphorylation | SSRSLSGSTNTVASE CCCCCCCCCCCCCCC | 18.33 | 27732954 | |
| 594 | Phosphorylation | SRSLSGSTNTVASEG CCCCCCCCCCCCCCC | 38.13 | 27732954 | |
| 596 | Phosphorylation | SLSGSTNTVASEGVT CCCCCCCCCCCCCCC | 19.96 | 27732954 | |
| 599 | Phosphorylation | GSTNTVASEGVTKDS CCCCCCCCCCCCCCC | 30.46 | 28985074 | |
| 709 | Methylation | IADNFCMRGLSNFYP HHHHHHHHCHHHHCH | 44.04 | - | |
| 746 | Phosphorylation | LELERCKSPTSDHVN CEEEECCCCCCCCCC | 36.72 | 28348404 | |
| 748 | Phosphorylation | LERCKSPTSDHVNGH EEECCCCCCCCCCCC | 54.61 | 28348404 | |
| 749 | Phosphorylation | ERCKSPTSDHVNGHC EECCCCCCCCCCCCC | 29.15 | 28348404 | |
| 763 | Phosphorylation | CTSPTSQSCSSGKRL CCCCCCCCCCCCCCC | 18.74 | - | |
| 765 | Phosphorylation | SPTSQSCSSGKRLSS CCCCCCCCCCCCCCC | 47.58 | - | |
| 766 | Phosphorylation | PTSQSCSSGKRLSSA CCCCCCCCCCCCCCC | 53.30 | - | |
| 771 | Phosphorylation | CSSGKRLSSADVSKV CCCCCCCCCCCHHHC | 27.75 | - | |
| 772 | Phosphorylation | SSGKRLSSADVSKVN CCCCCCCCCCHHHCC | 32.83 | - | |
| 793 | Phosphorylation | PPFRKAQSAACMEIS CCCHHHHHCCEEEEE | 23.77 | 27251275 | |
| 800 | Phosphorylation | SAACMEISLPVTTEE HCCEEEEECCCCCHH | 17.20 | - | |
| 812 | Phosphorylation | TEENRENSYNRSRSS CHHHHHCCCCCCCCC | 21.02 | - | |
| 816 | Phosphorylation | RENSYNRSRSSSISS HHCCCCCCCCCCCCC | 32.64 | 20363803 | |
| 818 | Phosphorylation | NSYNRSRSSSISSID CCCCCCCCCCCCCCC | 29.68 | 23663014 | |
| 819 | Phosphorylation | SYNRSRSSSISSIDK CCCCCCCCCCCCCCC | 30.49 | 23663014 | |
| 820 | Phosphorylation | YNRSRSSSISSIDKD CCCCCCCCCCCCCCC | 27.95 | 29255136 | |
| 822 | Phosphorylation | RSRSSSISSIDKDSK CCCCCCCCCCCCCCH | 24.16 | 20363803 | |
| 823 | Phosphorylation | SRSSSISSIDKDSKE CCCCCCCCCCCCCHH | 32.89 | 23663014 | |
| 878 | Phosphorylation | LADEQRFTEPVMVLP CCCCCCCCCCEEEEC | 41.38 | - | |
| 937 | Phosphorylation | RRKVVMNSSSASQEI HHHEEECCCCCCCCC | 13.94 | 24850871 | |
| 954 | Phosphorylation | HQYTIICSEKQAKVF CEEEEEECCCCCEEE | 37.10 | 24850871 | |
| 1010 | Phosphorylation | IMIMSLPSLRPMLDV EEEEECCCCCCCCCC | 42.16 | 24719451 | |
| 1052 | Phosphorylation | PTEIQRLTYSQEMCD HHHHHHCCCCHHHHH | 24.26 | 24043423 | |
| 1053 | Phosphorylation | TEIQRLTYSQEMCDN HHHHHCCCCHHHHHH | 16.98 | 24043423 | |
| 1054 | Phosphorylation | EIQRLTYSQEMCDNL HHHHCCCCHHHHHHH | 17.90 | 24043423 | |
| 1070 | Phosphorylation | DMLGDLFTPIETPEA HHHHHHCCCCCCHHH | 30.56 | 24043423 | |
| 1074 | Phosphorylation | DLFTPIETPEAQNRG HHCCCCCCHHHHHCC | 27.44 | 24043423 | |
| 1093 | Phosphorylation | LFGGSGQTFDREELF HHCCCCCCCCHHHHH | 30.91 | - | |
| 1111 | Phosphorylation | SAGKASRSLAQHIPG CCCHHHHHHHHCCCC | 26.09 | - | |
| 1121 | Phosphorylation | QHIPGPGSIEGMKGA HCCCCCCCHHCCCCC | 22.17 | - | |
| 1137 | Phosphorylation | GGVMGELTRARIALD CHHHHHHHHHHHHHC | 20.27 | - | |
| 1157 | Phosphorylation | LGELEEKTAGMMTSA HHHHHHHHHCCCCCH | 31.55 | - | |
| 1168 | Phosphorylation | MTSAEAFSKHAHELM CCCHHHHHHHHHHHH | 30.49 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of STB5L_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of STB5L_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of STB5L_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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