MLEC_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MLEC_RAT
• UniProt AC: Q5FVQ4
• Protein Name: Malectin
• Gene Name: Mlec
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 291
• Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
• Protein Description: Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity)..
• Protein Sequence: MLKPRAAEGAAVALLRLLLLLLLLPPELRDRGLGVAGAAGAGLPESVIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSTPEDQILYQTERYNEETFGYEVPVKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVSTFTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQPHPGLEKKEEEEEEEEYDEGSNLKRQTNKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	Succinylation	VHGIHFRKDPLEGRV ECCEEECCCCCCCCC	63.86	26843850
130	Phosphorylation	VLKFAEVYFAQSQQK EEEEEEEEEECCCCE	5.68	-
242	Phosphorylation	EEEYDEGSNLKRQTN HHHCCCCCCHHHHCC	36.62	22673903
267	N-linked_Glycosylation	PNPYASDNSSLMFPI CCCCCCCCCCCHHHH	30.88	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MLEC_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MLEC_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MLEC_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of MLEC_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.