dbPTM

PTMS_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PTMS_RAT
UniProt AC	P04550
Protein Name	Parathymosin
Gene Name	Ptms
Organism	Rattus norvegicus (Rat).
Sequence Length	102
Subcellular Localization
Protein Description	Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections..
Protein Sequence	MSEKSVEAAAELSAKDLKEKKDKVEEKAGRKERKKEVVEEEENGAEEEEEETAEDGEDDDEGDEEDEEEEEEEDEGPVRKRTAEEEDEADPKRQKTENGASA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSEKSVEAA ------CCHHHHHHH	54.45	3456585
2	Phosphorylation	------MSEKSVEAA ------CCHHHHHHH	54.45	23298284
4	Acetylation	----MSEKSVEAAAE ----CCHHHHHHHHH	53.12	22902405
5	Phosphorylation	---MSEKSVEAAAEL ---CCHHHHHHHHHH	22.57	29779826
13	Phosphorylation	VEAAAELSAKDLKEK HHHHHHHCHHHHHHH	25.44	28432305
15	Acetylation	AAAELSAKDLKEKKD HHHHHCHHHHHHHHH	61.28	25786129
18	Acetylation	ELSAKDLKEKKDKVE HHCHHHHHHHHHHHH	77.08	26302492
23	Acetylation	DLKEKKDKVEEKAGR HHHHHHHHHHHHHCH	61.50	22902405
27	Acetylation	KKDKVEEKAGRKERK HHHHHHHHHCHHHHH	42.51	22902405
52	Phosphorylation	AEEEEEETAEDGEDD CHHHHHHHCCCCCCC	38.33	21630457
82	Phosphorylation	EGPVRKRTAEEEDEA CCCCCCCCHHHCCCC	41.26	29779826
92	Acetylation	EEDEADPKRQKTENG HCCCCCHHHHCCCCC	68.92	22902405
92	Succinylation	EEDEADPKRQKTENG HCCCCCHHHHCCCCC	68.92	26843850

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PTMS_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PTMS_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PTMS_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PTMS_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PTMS_RAT

Related Literatures of Post-Translational Modification