SODC_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SODC_RAT
• UniProt AC: P07632
• Protein Name: Superoxide dismutase [Cu-Zn]
• Gene Name: Sod1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 154
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Destroys radicals which are normally produced within the cells and which are toxic to biological systems..
• Protein Sequence: MAMKAVCVLKGDGPVQGVIHFEQKASGEPVVVSGQITGLTEGEHGFHVHQYGDNTQGCTTAGPHFNPHSKKHGGPADEERHVGDLGNVAAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAMKAVCVL ------CCCEEEEEE	14.26	-
4	Acetylation	----MAMKAVCVLKG ----CCCEEEEEEEC	28.29	22902405
4	Succinylation	----MAMKAVCVLKG ----CCCEEEEEEEC	28.29	-
4	Succinylation	----MAMKAVCVLKG ----CCCEEEEEEEC	28.29	-
7	S-palmitoylation	-MAMKAVCVLKGDGP -CCCEEEEEEECCCC	3.38	-
10	Acetylation	MKAVCVLKGDGPVQG CEEEEEEECCCCEEE	34.26	22902405
10	Succinylation	MKAVCVLKGDGPVQG CEEEEEEECCCCEEE	34.26	-
10	Succinylation	MKAVCVLKGDGPVQG CEEEEEEECCCCEEE	34.26	-
92	Succinylation	LGNVAAGKDGVANVS CCCHHCCCCCCEEEE	46.73	-
92	Succinylation	LGNVAAGKDGVANVS CCCHHCCCCCCEEEE	46.73	-
92	Acetylation	LGNVAAGKDGVANVS CCCHHCCCCCCEEEE	46.73	22902405
99	Phosphorylation	KDGVANVSIEDRVIS CCCCEEEEHHHEEEE	21.77	29779826
106	Phosphorylation	SIEDRVISLSGEHSI EHHHEEEEECCCCEE	17.39	21738781
108	Phosphorylation	EDRVISLSGEHSIIG HHEEEEECCCCEEEC	35.03	23991683
112	Phosphorylation	ISLSGEHSIIGRTMV EEECCCCEEECEEEE	16.17	23991683
123	Acetylation	RTMVVHEKQDDLGKG EEEEEEECCCCCCCC	44.12	22902405
123	Succinylation	RTMVVHEKQDDLGKG EEEEEEECCCCCCCC	44.12	-
123	Succinylation	RTMVVHEKQDDLGKG EEEEEEECCCCCCCC	44.12	26843850
129	Acetylation	EKQDDLGKGGNEEST ECCCCCCCCCCCCCC	71.58	22902405
129	Succinylation	EKQDDLGKGGNEEST ECCCCCCCCCCCCCC	71.58	26843850
137	Acetylation	GGNEESTKTGNAGSR CCCCCCCCCCCCCHH	64.81	22902405
137	Succinylation	GGNEESTKTGNAGSR CCCCCCCCCCCCCHH	64.81	-
137	Succinylation	GGNEESTKTGNAGSR CCCCCCCCCCCCCHH	64.81	-
138	Phosphorylation	GNEESTKTGNAGSRL CCCCCCCCCCCCHHE	35.44	23984901
143	Phosphorylation	TKTGNAGSRLACGVI CCCCCCCHHEEEEEE	23.01	23984901

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SODC_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SODC_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SODC_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PDIA1_RAT	P4hb	physical	23061969

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.