GPDM_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPDM_RAT
• UniProt AC: P35571
• Protein Name: Glycerol-3-phosphate dehydrogenase, mitochondrial
• Gene Name: Gpd2
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 727
• Subcellular Localization: Mitochondrion.
• Protein Sequence: MAFQKVVKGTILMGGGALATVLGLSQFAHYRRKQVSLAYVEAATCFSEPVNREPPSREAQLMTLQNTSEFDILVIGGGATGCGCALDAVTRGLKTALVERNDFASGTSSRSTKLIHGGVRYLQKAITNLDVEQYRMVKEALHERANLLEIAPHLSAPLPIMLPLYKWWQLPYYWVGIKMYDLVAGSHCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPETGKERVSGARCKDVLTGHEFNVRAKCVINATGPFTDSVRKMDDNDVVPICQPSAGVHIVMPGYYSPENMGLLDPATSDGRVIFFLPWEKMTIAGTTDSPTDVTHHPIPSEDDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDPKSANTQSISRNHVVEVSDSGLITIAGGKWTTYRSMAEDTVNKAVKLHNLNAGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAKTYGDKAFDVAKMASVTGKRWPVVGVRLVSEFPYIEAEVKYGIKEYACTAVDMISRRTRLAFLNVQAAEEALPKIVELMGRELNWSELRKQEELETATRFLYYEMGYKSRTEQLTDSTEISLLPPDIDRYKKRFHMFDEDEKGFITIVDVQRVLESINVQMDEDTLHEILCEVDLNKNGQVELHEFLQLMSAVHTGRVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
94	Acetylation	DAVTRGLKTALVERN HHHHCCHHHHHHHCC	34.28	22902405
121	Phosphorylation	LIHGGVRYLQKAITN EEECHHHHHHHHHHC	15.86	-
124	Acetylation	GGVRYLQKAITNLDV CHHHHHHHHHHCCCH	38.88	22902405
138	Acetylation	VEQYRMVKEALHERA HHHHHHHHHHHHHHH	28.11	73913977
209	Acetylation	EHFPMLQKDKLVGAI HHCCCCCCCCEEEEE	53.52	22902405
211	Acetylation	FPMLQKDKLVGAIVY CCCCCCCCEEEEEEE	52.70	22902405
436	Acetylation	LITIAGGKWTTYRSM EEEEECCEEEEEHHH	40.21	22902405
450	Acetylation	MAEDTVNKAVKLHNL HCHHHHHHHHHHCCC	50.66	22902405
453	Acetylation	DTVNKAVKLHNLNAG HHHHHHHHHCCCCCC	49.22	22902405
473	Acetylation	GLFLQGGKDWSPTLY EEEEECCCCCCCEEH	63.95	22902405
504	Acetylation	LAKTYGDKAFDVAKM HHHHHCCHHHHHHHH	46.74	22902405
510	Acetylation	DKAFDVAKMASVTGK CHHHHHHHHHHCCCC	34.54	22902405
588	Acetylation	LNWSELRKQEELETA CCHHHHHHHHHHHHH	74.76	22902405
601	Phosphorylation	TATRFLYYEMGYKSR HHHHHHHHHCCCCCC	11.11	18331841
606	Acetylation	LYYEMGYKSRTEQLT HHHHCCCCCCCCCCC	27.94	22902405
630	Acetylation	PDIDRYKKRFHMFDE CCHHHHHHHHCCCCC	51.89	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPDM_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPDM_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPDM_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of GPDM_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.