COX5B_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: COX5B_RAT
• UniProt AC: P12075
• Protein Name: Cytochrome c oxidase subunit 5B, mitochondrial
• Gene Name: Cox5b
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 129
• Subcellular Localization: Mitochondrion inner membrane.
• Protein Description: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport..
• Protein Sequence: MASRLLRGVGALAAQALRAHGPRGVAATRSMASGGGVPTDEEQATGLEREIMIAAQRGLDPYNMLPPKAASGTKEDPNLVPSVSNKRIVGCICEEDNCTVIWFWLHQGESQRCPNCGTHYKLVPYQMVH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	Acetylation	PYNMLPPKAASGTKE CCCCCCCCCCCCCCC	55.43	22902405
74	Acetylation	PKAASGTKEDPNLVP CCCCCCCCCCCCCCC	64.74	22902405
86	Acetylation	LVPSVSNKRIVGCIC CCCCCCCCEEEEEEE	35.68	22902405
121	Acetylation	PNCGTHYKLVPYQMV CCCCCCCEEEECCCC	35.09	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of COX5B_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of COX5B_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of COX5B_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of COX5B_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.