| UniProt ID | SCFD1_RAT | |
|---|---|---|
| UniProt AC | Q62991 | |
| Protein Name | Sec1 family domain-containing protein 1 | |
| Gene Name | Scfd1 | |
| Organism | Rattus norvegicus (Rat). | |
| Sequence Length | 637 | |
| Subcellular Localization |
Cytoplasm . Endoplasmic reticulum membrane Peripheral membrane protein . Golgi apparatus, Golgi stack membrane Peripheral membrane protein . |
|
| Protein Description | Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.. | |
| Protein Sequence | MVGSKMAASIRERQTVALKRMLNFNVPHVKNSPGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIRDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAANAVTQVAKVFDQYLNFITLEEDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDPLGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPTGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKKALTDAGCNLSPLQYIKQWKAFAKMASTPASYGNTTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKGKQGKHILYGCSEIFNATQFIKQLSQLGQK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 32 | Phosphorylation | NVPHVKNSPGEPVWK CCCCCCCCCCCCEEE | 28.67 | 27097102 | |
| 292 | Phosphorylation | NRVNLEESTGVENSP HCCCCHHHCCCCCCC | 22.53 | 27097102 | |
| 293 | Phosphorylation | RVNLEESTGVENSPT CCCCHHHCCCCCCCC | 48.83 | 27097102 | |
| 298 | Phosphorylation | ESTGVENSPTGARPK HHCCCCCCCCCCCCC | 15.44 | 23712012 | |
| 300 | Phosphorylation | TGVENSPTGARPKRK CCCCCCCCCCCCCCC | 43.21 | 27097102 | |
| 311 | Phosphorylation | PKRKNKKSYDLTPVD CCCCCCCCCCCCCHH | 26.03 | 28432305 | |
| 312 | Phosphorylation | KRKNKKSYDLTPVDK CCCCCCCCCCCCHHH | 24.69 | 30181290 | |
| 315 | Phosphorylation | NKKSYDLTPVDKFWQ CCCCCCCCCHHHHHH | 20.54 | 30181290 | |
| 319 | Acetylation | YDLTPVDKFWQKHKG CCCCCHHHHHHHHCC | 49.05 | 22902405 | |
| 416 | Phosphorylation | KARKLDVYFEYEEKI HHCCCEEEEEEHHHH | 7.14 | 26022182 | |
| 428 | Phosphorylation | EKIMSKTTLDKSLLD HHHCCCCCCCHHHHH | 36.37 | 26022182 | |
| 521 | Phosphorylation | LLSRVMNTGSQFVME HHHHHHHCCCHHHHH | 21.80 | 25575281 | |
| 523 | Phosphorylation | SRVMNTGSQFVMEGV HHHHHCCCHHHHHHH | 20.57 | 25575281 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SCFD1_RAT !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SCFD1_RAT !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SCFD1_RAT !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SCFD1_RAT !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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