dbPTM

OS9_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OS9_RAT
UniProt AC	Q5RKH6
Protein Name	Protein OS-9
Gene Name	Os9
Organism	Rattus norvegicus (Rat).
Sequence Length	666
Subcellular Localization	Endoplasmic reticulum lumen.
Protein Description	Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 (By similarity)..
Protein Sequence	MAAEALLSSLLGLLFLGLLLPAHLTGGVGSLNLEELSEMRYGIQILPLPVMGGQSQASDVVVVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGDVLYLGYYQSAFNWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGKPREAEVRFLCDEGAGISGDYIDRVDEPFSCSYVLSIRTSRLCPHPLLRPPASAAPQAILCHPALQPDEYMAYLQRQAESKQHEEKVTEEVQDTDHQVWSGSKAAGAPPKKEDVSPTKEDKESEFWKMLQEPEEQATGTEEAQAGEQDLNHEAAADPAPAPPTDFQNNVQVKLIRSPADLIRLIEELKGAEKGKPSVRQEQPGDDTTEAPQREAEAKGKGGEPRGLVEEEDGDEEEEDEDEDEQQLLGEFEKELEGMLLPSDRERLRSEVKAGMERELENIIQETEKELDPEGLRKESEREQAILALTSTLDKLIKRLQESQSPELVQKYKKRRVVPQKPPPSPHPTEEEPEHRVRVRVTKLRHGGPNQDLTVLEMNRENPQLKQIEGLVTEVLEREGLTAEGKIEIKIVRPGAEGKEEDTRWLTDEDTRNLKEIFFNILVQGAEEANKERQRQSELESNYRRVWGSPGGEDTGDLDEFDF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
177	N-linked_Glycosylation	YHSQTYGNGSKCDLN HHHCCCCCCCCCCCC	40.94	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OS9_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of OS9_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OS9_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of OS9_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OS9_RAT

Related Literatures of Post-Translational Modification