dbPTM

14333_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	14333_ARATH
UniProt AC	P42644
Protein Name	14-3-3-like protein GF14 psi {ECO:0000303\|PubMed:7972511}
Gene Name	GRF3 {ECO:0000303\|PubMed:7870824}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	255
Subcellular Localization	Cytoplasm . Nucleus . Translocates from the cytosol to the nucleus when phosphorylated.
Protein Description	Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. [PubMed: 7972511]
Protein Sequence	MSTREENVYMAKLAEQAERYEEMVEFMEKVAKTVDVEELSVEERNLLSVAYKNVIGARRASWRIISSIEQKEESKGNEDHVAIIKDYRGKIESELSKICDGILNVLEAHLIPSASPAESKVFYLKMKGDYHRYLAEFKAGAERKEAAESTLVAYKSASDIATAELAPTHPIRLGLALNFSVFYYEILNSPDRACSLAKQAFDDAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMTDEAGDEIKEASKPDGAE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSTREENVY ------CCHHHHHHH	35.85	25561503
3	Phosphorylation	-----MSTREENVYM -----CCHHHHHHHH	40.58	25561503
9	Phosphorylation	STREENVYMAKLAEQ CHHHHHHHHHHHHHH	11.70	25561503
48	Phosphorylation	VEERNLLSVAYKNVI HHHHHHHHHHHHHHH	14.10	25561503
66	Phosphorylation	RASWRIISSIEQKEE HHHHHHHHHHHHHHH	23.92	-
156	Phosphorylation	STLVAYKSASDIATA HHHHEECCHHHHHCC	21.96	25561503
158	Phosphorylation	LVAYKSASDIATAEL HHEECCHHHHHCCCC	36.32	25561503
162	Phosphorylation	KSASDIATAELAPTH CCHHHHHCCCCCCCC	22.46	22092075
189	Phosphorylation	FYYEILNSPDRACSL HHHHHHCCHHHHHHH	25.40	-
210	Phosphorylation	DAIAELDTLGEESYK HHHHHHHCCCCHHHC	49.65	-
231	Phosphorylation	QLLRDNLTLWTSDMT HHHHCCCCEEECCCC	26.89	23776212
231 (in isoform 2)	Phosphorylation	-	26.89	23776212
234	Phosphorylation	RDNLTLWTSDMTDEA HCCCCEEECCCCCHH	20.26	23776212
234 (in isoform 2)	Phosphorylation	-	20.26	23776212
235	Phosphorylation	DNLTLWTSDMTDEAG CCCCEEECCCCCHHH	17.50	23776212
235 (in isoform 2)	Phosphorylation	-	17.50	23776212
238	Phosphorylation	TLWTSDMTDEAGDEI CEEECCCCCHHHHHH	35.36	30291188
238 (in isoform 2)	Phosphorylation	-	35.36	23776212
240 (in isoform 2)	Phosphorylation	-	45.44	23776212
248 (in isoform 2)	Phosphorylation	-	20.18	23776212
249	Phosphorylation	GDEIKEASKPDGAE- HHHHHHHHCCCCCC-	45.90	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of 14333_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of 14333_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of 14333_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IDH3_ARATH	IDH-III	physical	22104211
MDHC1_ARATH	AT1G04410	physical	22104211
MDHC2_ARATH	AT5G43330	physical	22104211
TMKL1_ARATH	TMKL1	physical	21423366
M1090_ARATH	ArthMp095	physical	21094157
M450_ARATH	ArthMp038	physical	21094157
SKIP2_ARATH	SKIP2	physical	21094157
WAKLR_ARATH	AT5G66790	physical	21094157
SDHA1_ARATH	SDH1-1	physical	21094157
GMD1_ARATH	GMD1	physical	21094157
RAD17_ARATH	ATRAD17	physical	21094157
STR16_ARATH	STR16	physical	21094157
CRWN4_ARATH	LINC4	physical	21094157
14338_ARATH	GRF8	physical	21094157
PDX2_ARATH	PDX2	physical	21094157
PER67_ARATH	AT5G58390	physical	21094157
CNGC5_ARATH	CNGC5	physical	21094157
PMA3_ARATH	HA3	physical	21094157
DNLI4_ARATH	ATLIG4	physical	21094157
GPDL4_ARATH	SVL1	physical	21094157
THI4_ARATH	THI1	physical	21094157
THIC1_ARATH	ACAT2	physical	21094157
THIC2_ARATH	AT5G47720	physical	21094157
ERF80_ARATH	ERF9	physical	21094157
PHT11_ARATH	PHT1;1	physical	21094157
MDHC2_ARATH	AT5G43330	physical	21094157
MDHC1_ARATH	AT1G04410	physical	21094157
CSN4_ARATH	COP8	physical	21094157
XPB1_ARATH	XPB1	physical	21094157
VTI11_ARATH	SGR4	physical	21094157
C85A1_ARATH	BR6OX1	physical	21094157
14333_ARATH	GRF3	physical	21094157
2A5K_ARATH	AT5G25510	physical	21094157
SM3L2_ARATH	RAD5	physical	21094157
DNAJ2_ARATH	J2	physical	21094157
CNX1_ARATH	B73	physical	21094157
PIST_ARATH	PI	physical	21094157
RAN1_ARATH	RAN-1	physical	21094157
RAN2_ARATH	RAN2	physical	21094157
RAN3_ARATH	RAN3	physical	21094157
ATG5_ARATH	APG5	physical	21094157
COL1_ARATH	COL1	physical	21094157
SUT41_ARATH	SULTR4;1	physical	21094157
ALF4_ARATH	ALF4	physical	21094157
14336_ARATH	GRF6	physical	21094157
POT7_ARATH	KUP7	physical	21094157
HEM3_ARATH	HEMC	physical	21094157
DNAJ6_ARATH	ATJ6	physical	21094157
DME_ARATH	DME	physical	21094157
NAC78_ARATH	NAC2	physical	21094157
EIN2_ARATH	EIN2	physical	21094157
FBL25_ARATH	AT5G02920	physical	21094157
MD37E_ARATH	HSC70-1	physical	21094157
CP18C_ARATH	ROC1	physical	21094157
CK5P1_ARATH	AT4G36390	physical	21094157
HMA6_ARATH	PAA1	physical	21094157
GCSP1_ARATH	GLDP1	physical	21094157
PMA2_ARATH	HA2	physical	21094157
R15A5_ARATH	rps15ae	physical	21094157
HXK1_ARATH	HXK1	physical	21094157
TOR1_ARATH	TOR1	physical	21094157
NIFU3_ARATH	NFU3	physical	21094157
FWA_ARATH	FWA	physical	21094157
AKT2_ARATH	KT2/3	physical	21094157
RETOL_ARATH	AT4G20830	physical	21094157
NIP12_ARATH	NIP1;2	physical	21094157
HFA1A_ARATH	HSF1	physical	21094157
PER41_ARATH	AT4G17690	physical	21094157
PER65_ARATH	AT5G47000	physical	21094157
EF100_ARATH	ERF-1	physical	21094157
PRL1_ARATH	PRL1	physical	21094157
PUX5_ARATH	PUX5	physical	21094157
AB30G_ARATH	PDR2	physical	21094157
DRL23_ARATH	AT4G10780	physical	21094157
SPT16_ARATH	SPT16	physical	21094157
FBL21_ARATH	AT4G05470	physical	21094157
METK2_ARATH	SAM-2	physical	21094157
METK4_ARATH	MTO3	physical	21094157
METK3_ARATH	MAT3	physical	21094157
METK1_ARATH	SAM1	physical	21094157
AB14C_ARATH	MRP10	physical	21094157
PME37_ARATH	VGDH2	physical	21094157
IF4G_ARATH	EIF4G	physical	21094157
VILI3_ARATH	VLN3	physical	21094157
ATX3H_ARATH	AT3G54130	physical	21094157
AB27G_ARATH	AT3G52310	physical	21094157
ODP21_ARATH	LTA3	physical	21094157
SUGP1_ARATH	AT3G52120	physical	21094157
CML9_ARATH	CAM9	physical	21094157
GSA2_ARATH	GSA2	physical	21094157
ATM_ARATH	ATM	physical	21094157
MECR_ARATH	AT3G45770	physical	21094157
AB19B_ARATH	ABCB19	physical	21094157
AB17B_ARATH	PGP17	physical	21094157
AB16B_ARATH	PGP16	physical	21094157
CH60A_ARATH	HSP60	physical	21094157
ACT2_ARATH	ACT2	physical	21094157
TONS_ARATH	TSK	physical	21094157
MSH2_ARATH	MSH2	physical	21094157
CAX2_ARATH	CAX2	physical	21094157
HAC5_ARATH	HAC5	physical	21094157
BOR3_ARATH	AT3G06450	physical	21094157
ERDL8_ARATH	AT3G05150	physical	21094157
SUVR4_ARATH	SUVR4	physical	21094157
RGL2_ARATH	RGL2	physical	21094157
RH41_ARATH	AT3G02065	physical	21094157
MTP1_ARATH	ZAT	physical	21094157
FLA8_ARATH	FLA8	physical	21094157
MAP1A_ARATH	MAP1A	physical	21094157
PER26_ARATH	AT2G43480	physical	21094157
SFGH_ARATH	SFGH	physical	21094157
PI5K5_ARATH	PIP5K5	physical	21094157
AGT22_ARATH	AGT3	physical	21094157
AB1B_ARATH	ABCB1	physical	21094157
WRK35_ARATH	WRKY35	physical	21094157
SCAR1_ARATH	WAVE1	physical	21094157
RH21_ARATH	AT2G33730	physical	21094157
THIK2_ARATH	PKT3	physical	21094157
GSTFA_ARATH	GSTF10	physical	21094157
RPT2_ARATH	RPT2	physical	21094157
BL1S1_ARATH	AT2G30330	physical	21094157
PUSH_ARATH	AT2G30320	physical	21094157
WRK25_ARATH	WRKY25	physical	21094157
AB3G_ARATH	AT2G28070	physical	21094157
AGO5_ARATH	AGO5	physical	21094157
PEX10_ARATH	PEX10	physical	21094157
ARR12_ARATH	RR12	physical	21094157
GLR22_ARATH	GLR2.2	physical	21094157
GH33_ARATH	GH3.3	physical	21094157
ATHB6_ARATH	HB6	physical	21094157
PER17_ARATH	AT2G22420	physical	21094157
ATL12_ARATH	AT2G20030	physical	21094157
RECA3_ARATH	AT2G19490	physical	21094157
GGPP4_ARATH	GGPS4	physical	21094157
CP19A_ARATH	ROC3	physical	21094157
RH33_ARATH	AT2G07750	physical	21094157
DEF10_ARATH	LCR72	physical	21094157
BRL2_ARATH	BRL2	physical	21094157
RGA_ARATH	RGA1	physical	21094157
RPI2_ARATH	RPI2	physical	21094157
LPP1_ARATH	PAP1	physical	21094157
HAC1_ARATH	HAC1	physical	21094157
VATA_ARATH	VHA-A	physical	21094157
STP14_ARATH	STP14	physical	21094157
PSD3B_ARATH	AT1G75990	physical	21094157
OTC_ARATH	OTC	physical	21094157
SUVH3_ARATH	SUVH3	physical	21094157
SYFB_ARATH	AT1G72550	physical	21094157
CSN5B_ARATH	CSN5B	physical	21094157
GUN8_ARATH	GH9B1	physical	21094157
UPL2_ARATH	UPL2	physical	21094157
COL6_ARATH	AT1G68520	physical	21094157
HSFA8_ARATH	HSFA8	physical	21094157
CMTA4_ARATH	AT1G67310	physical	21094157
ETR1_ARATH	ETR1	physical	21094157
1A110_ARATH	ACS10	physical	21094157
WRKY6_ARATH	WRKY6	physical	21094157
RH20_ARATH	AT1G55150	physical	21094157
LOX1_ARATH	LOX1	physical	21094157
M3K2_ARATH	NP2	physical	21094157
RHM2_ARATH	MUM4	physical	21094157
TLP7_ARATH	TLP7	physical	21094157
DF124_ARATH	LCR16	physical	21094157
ARFO_ARATH	ARF15	physical	21094157
ZIP10_ARATH	ZIP10	physical	21094157
AKH1_ARATH	AK-HSDH I	physical	21094157
DR111_ARATH	DRT111	physical	21094157
OTUBL_ARATH	AT1G28120	physical	21094157
AB13B_ARATH	PGP13	physical	21094157
14312_ARATH	GRF12	physical	21094157
PIN7_ARATH	PIN7	physical	21094157
SUT13_ARATH	SULTR1;3	physical	21094157
PI5K1_ARATH	PIP5K1	physical	21094157
RH42_ARATH	AT1G20920	physical	21094157
CATA3_ARATH	CAT3	physical	21094157
FCL2_ARATH	GER2	physical	21094157
PMA10_ARATH	AHA10	physical	21094157
LBD3_ARATH	ASL9	physical	21094157
XTH28_ARATH	XTH28	physical	21094157
DRL1_ARATH	AT1G12280	physical	21094157
NT101_ARATH	AT1G10490	physical	21094157
ZFP5_ARATH	ZFP5	physical	21094157
DRP2A_ARATH	ADL6	physical	21094157
PUR2_ARATH	AT1G09830	physical	21094157
PIF3_ARATH	PIF3	physical	21094157
PBL9_ARATH	APK1A	physical	21094157
CRTSO_ARATH	CRTISO	physical	21094157
ATL1_ARATH	AT1G04360	physical	21094157
IAA17_ARATH	AXR3	physical	21094157
KCS2_ARATH	KCS2	physical	21094157
PORC_ARATH	POR C	physical	21094157
GLN11_ARATH	GSR 1	physical	21094157
GLN14_ARATH	GLN1;4	physical	21094157
GLN12_ARATH	GSR2	physical	21094157
ATL31_ARATH	CNI1	physical	21094157
EMS1_ARATH	EMS1	physical	21094157
AKT5_ARATH	KT5	physical	21094157
PANK2_ARATH	PANK2	physical	21094157
PI5K4_ARATH	PIP5K4	physical	21094157
DOF36_ARATH	OBP3	physical	21094157
AB26G_ARATH	WBC27	physical	21094157
CD48C_ARATH	CDC48C	physical	21094157
AAT1_ARATH	ASP1	physical	21094157
PLT4_ARATH	AT2G20780	physical	21094157
DRE2D_ARATH	AT1G75490	physical	21094157
TMK1_ARATH	TMK1	physical	21094157
PSD3A_ARATH	EMB2719	physical	21094157
CNG10_ARATH	CNGC10	physical	21094157
1A12_ARATH	ACS2	physical	25122152
1A15_ARATH	ACS5	physical	25122152
1A16_ARATH	ACS6	physical	25122152
1A18_ARATH	ACS8	physical	25122152
1A111_ARATH	ACS11	physical	25122152
14333_ARATH	GRF3	physical	10622729
14336_ARATH	GRF6	physical	10622729

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of 14333_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-238, AND MASSSPECTROMETRY.	19376835 [Abstract]