AKH1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AKH1_ARATH
• UniProt AC: Q9SA18
• Protein Name: Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic
• Gene Name: AKHSDH1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 911
• Subcellular Localization: Plastid, chloroplast.
• Protein Sequence: MPVVSLAKVVTSPAVAGDLAVRVPFIYGKRLVSNRVSFGKLRRRSCIGQCVRSELQSPRVLGSVTDLALDNSVENGHLPKGDSWAVHKFGGTCVGNSERIKDVAAVVVKDDSERKLVVVSAMSKVTDMMYDLIHRAESRDDSYLSALSGVLEKHRATAVDLLDGDELSSFLARLNDDINNLKAMLRAIYIAGHATESFSDFVVGHGELWSAQMLAAVVRKSGLDCTWMDARDVLVVIPTSSNQVDPDFVESEKRLEKWFTQNSAKIIIATGFIASTPQNIPTTLKRDGSDFSAAIMSALFRSHQLTIWTDVDGVYSADPRKVSEAVVLKTLSYQEAWEMSYFGANVLHPRTIIPVMKYDIPIVIRNIFNLSAPGTMICRQIDDEDGFKLDAPVKGFATIDNLALVNVEGTGMAGVPGTASAIFSAVKEVGANVIMISQASSEHSVCFAVPEKEVKAVSEALNSRFRQALAGGRLSQIEIIPNCSILAAVGQKMASTPGVSATFFNALAKANINIRAIAQGCSEFNITVVVKREDCIRALRAVHSRFYLSRTTLAVGIIGPGLIGGTLLDQIRDQAAVLKEEFKIDLRVIGITGSSKMLMSESGIDLSRWRELMKEEGEKADMEKFTQYVKGNHFIPNSVMVDCTADADIASCYYDWLLRGIHVVTPNKKANSGPLDQYLKIRDLQRKSYTHYFYEATVGAGLPIISTLRGLLETGDKILRIEGIFSGTLSYLFNNFVGTRSFSEVVAEAKQAGFTEPDPRDDLSGTDVARKVTILARESGLKLDLEGLPVQNLVPKPLQACASAEEFMEKLPQFDEELSKQREEAEAAGEVLRYVGVVDAVEKKGTVELKRYKKDHPFAQLSGADNIIAFTTKRYKEQPLIVRGPGAGAQVTAGGIFSDILRLAFYLGAPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
323	Phosphorylation	SADPRKVSEAVVLKT CCCHHCCCEEEEEEE	23.91	28011693
665	Phosphorylation	LRGIHVVTPNKKANS HCCEEEECCCCCCCC	21.76	24894044
689	Phosphorylation	RDLQRKSYTHYFYEA HHHHHCCCCEEEECC	10.69	19880383
694	Phosphorylation	KSYTHYFYEATVGAG CCCCEEEECCCCCCC	9.48	19880383
706	Phosphorylation	GAGLPIISTLRGLLE CCCCCHHHHHHHHHH	23.31	19880383
707	Phosphorylation	AGLPIISTLRGLLET CCCCHHHHHHHHHHH	15.29	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AKH1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AKH1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AKH1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of AKH1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.