NT101_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NT101_ARATH
• UniProt AC: Q9XIK4
• Protein Name: RNA cytidine acetyltransferase 1 {ECO:0000255|HAMAP-Rule:MF_03211}
• Gene Name: At1g10490
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1028
• Subcellular Localization: Nucleus, nucleolus .
• Protein Description: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation..
• Protein Sequence: MRKKVDERIRTLIENGVKLRHRSMFVIIGDKARDQIVNLHHILSKSVVKSNPSVLWCYKNRLDISSHNKKRAKQLKKMKERGQLDPEKLDAFSLFLDVVDVTHCLYKDSERILGNTFGICILQDFEALTPNLLARTIETVEGGGLVVLLLQSLASLTSLCTMVMDVHDRFRTESHSEASGRFNERFLLSLASCKACVVMDDELNLLPLSSHIKSITKVPTKEDSEALSEAERDLKSLKDALNDDFPVGPLINKCCTLDQGKAVVTFFDAILDKTLRSIVALIASRGRGKSAALGLAVAGAVAAGYSNIYVTAPSPDNLKTVFEFVCKGFDALEYKEHLEYDVVRSVNPEFNKAIVRINIFKQHRQTIQYIQPHEHEKLSQVELLVIDEAAAIPLPVVKSLLGPYLVFLSSTVSGYEGTGRSLSLKLLQQLEEQSRAPVTGVEGSLSGCLFKKIELSESIRYASGDPIESWLNGLLCLDVANCLPNPACHPLPSQCDLYYVNRDTLFSYHKDSELFLQRMMALCVSSHYKNSPNDLQLLSDAPAHHLFVLLGPVDESKNQLPDILCVIQVCLEGQISRKSAEKSLREGHSPHGDQIPWKFCEQFRDVVFPKLSGARIVRIAVHPNAMKMGYGSAAVELLTRYFEGQLASISEGDDELEVEPSPVRVTEAAAKVSLLEEQIKPRANLPPLLVPLRDRRPERLHYIGVSFGLTLDLFRFWRKHKFAPFYISQIPSAVTGEHTCMLLKPLTLSNDEFEVDESDELGFFAPFYKDFRIRFSKLLSDKFKKMDYKLAMSVLNPKINFPEVDLTGNSPDGFLKKLDGVLSPYDMERFRAYTANLVDFNLVYDICKTLAHHYFQEKLPVSLSYVQASVLLCLGLQESDFSSIERQMQLERGQIYSLLLKVGKKLYKYLNGIATKELESTLPRLKDRVLEPHKVSVDEDLREGAKEVEEQMRARIEELLDPELLDQFAIGDKEAEALQKSKISSSGLISIESTKTDNKKEKPSGFDKSAKKRGNDKHSSTSNKKRRA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	GVKLRHRSMFVIIGD CCCCCCCCEEEEEEC		25561503
65	Phosphorylation	YKNRLDISSHNKKRA ECCCCCCCHHHHHHH		30407730
66	Phosphorylation	KNRLDISSHNKKRAK CCCCCCCHHHHHHHH		30407730
423	Phosphorylation	EGTGRSLSLKLLQQL CCCCHHHHHHHHHHH		28011693
648	Phosphorylation	YFEGQLASISEGDDE HHHCCEEECCCCCCC		30407730
650	Phosphorylation	EGQLASISEGDDELE HCCEEECCCCCCCCE		30407730
661	Phosphorylation	DELEVEPSPVRVTEA CCCEECCCCCCCHHH		30407730
990	Phosphorylation	ISSSGLISIESTKTD CCCCCCEEEEECCCC		25368622
993	Phosphorylation	SGLISIESTKTDNKK CCCEEEEECCCCCCC		25368622
994	Phosphorylation	GLISIESTKTDNKKE CCEEEEECCCCCCCC		25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NT101_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NT101_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NT101_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of NT101_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.