dbPTM

2A5K_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	2A5K_ARATH
UniProt AC	Q93YV6
Protein Name	Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform
Gene Name	B'KAPPA
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	500
Subcellular Localization	Cytoplasm .
Protein Description	The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment..
Protein Sequence	MFKQFLSKLPRKSSKSDSGELNRSSSGPVSSPVQRSGTSGGGSGPVRSNSGKRMSSAVFPASVVAGIEPLVPFKDVPSSEKLNLFVSKVSLCCVTFDFSDPGKNSIEKDVKRQTLLELLDFVASGSVKFTEPAILAMCRMCAVNLFRVFPPNYRSSSGGENDDDEPMFDPAWPHLQIVYDLLLKFITSPCLDAKVAKKYLDHAFIVRLLDLFDSEDPRERECLKTILHRVYGKFMVHRPFVRKSMSNIFYRFVFETEKHSGIAELLEIFGSIVSGFALPLKEEHKIFLWRVLIPLHKPKSVGNYFQQLSYCITQFIDKEPKLGSVVIKGLLKFWPITNSQKEVMFLGEVEEIVEAMSVMEFQKIMVPLFLRIACCVTSSHFQVSERALFLWNNDQIVNLIGHNRQAILPIMFTALEKNAQNHWNQSVLNLTLNVRKMFCEMDEALFMSCHARFKEDEAKQCSAAEKRKEVWARLENAASMKPITGKTAVLVTPRATSIAC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
25	Phosphorylation	SGELNRSSSGPVSSP CCCCCCCCCCCCCCC	25561503
26	Phosphorylation	GELNRSSSGPVSSPV CCCCCCCCCCCCCCC	25561503
496	Phosphorylation	VLVTPRATSIAC--- EEECCCCCCCCC---	19880383
497	Phosphorylation	LVTPRATSIAC---- EECCCCCCCCC----	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of 2A5K_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of 2A5K_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of 2A5K_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of 2A5K_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of 2A5K_ARATH

Related Literatures of Post-Translational Modification