dbPTM

14338_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	14338_ARATH
UniProt AC	P48348
Protein Name	14-3-3-like protein GF14 kappa
Gene Name	GRF8
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	248
Subcellular Localization	Nucleus . Cytoplasm . Translocates from the cytosol to the nucleus when phosphorylated.
Protein Description	Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. Involved in the regulation of nutrient metabolism. [PubMed: 22104211 Negative regulator of freezing tolerance that modulates cold-responsive C-repeat-binding factors (CBF) DREB1A AND DREB1B proteins stability by facilitating their ubiquitin-mediated degradation]
Protein Sequence	MATTLSRDQYVYMAKLAEQAERYEEMVQFMEQLVSGATPAGELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEESRKNEEHVSLVKDYRSKVETELSSICSGILRLLDSHLIPSATASESKVFYLKMKGDYHRYLAEFKSGDERKTAAEDTMIAYKAAQDVAVADLAPTHPIRLGLALNFSVFYYEILNSSEKACSMAKQAFEEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQEQMDEA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	Phosphorylation	VEERNLLSVAYKNVI HHHHHHHHHHHHHHH	14.10	25561503
70	Phosphorylation	RAAWRIVSSIEQKEE HHHHHHHHHHHHHHH	24.19	28344081
91	Phosphorylation	HVSLVKDYRSKVETE HHHHHHHHHHHHHHH	15.86	22074104
112	Phosphorylation	GILRLLDSHLIPSAT HHHHHHHHCCCCCCC	21.84	-
155	Sulfoxidation	KTAAEDTMIAYKAAQ HCCHHHHHHHHHHHH	2.26	25693801
193	Phosphorylation	FYYEILNSSEKACSM HHHHHHCCCHHHHHH	36.11	-
214	Phosphorylation	EAIAELDTLGEESYK HHHHHHHCCCCHHHC	49.65	23328941

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of 14338_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of 14338_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of 14338_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BZR1_ARATH	BZR1	physical	17873094
IDH3_ARATH	IDH-III	physical	22104211
MDHC1_ARATH	AT1G04410	physical	22104211
MDHC2_ARATH	AT5G43330	physical	22104211
HDA5_ARATH	HDA05	physical	22363501
FB316_ARATH	AT1G61340	physical	22920997
KCO1_ARATH	ATKCO1	physical	25189593
BZR1_ARATH	BZR1	physical	20387034
BZR2_ARATH	BES1	physical	20387034
SKIP2_ARATH	SKIP2	physical	21094157
SDHA1_ARATH	SDH1-1	physical	21094157
GMD1_ARATH	GMD1	physical	21094157
RAD17_ARATH	ATRAD17	physical	21094157
14338_ARATH	GRF8	physical	21094157
SDHB3_ARATH	SDH2-3	physical	21094157
AB28G_ARATH	AT5G60740	physical	21094157
PHOT2_ARATH	PHOT2	physical	21094157
CNGC5_ARATH	CNGC5	physical	21094157
PMA3_ARATH	HA3	physical	21094157
HATB_ARATH	HAG2	physical	21094157
GPDL4_ARATH	SVL1	physical	21094157
FTSZ1_ARATH	FTSZ1-1	physical	21094157
DPNPH_ARATH	HL	physical	21094157
MRE11_ARATH	MRE11	physical	21094157
OMT1_ARATH	OMT1	physical	21094157
AB8G_ARATH	AT5G52860	physical	21094157
CPSF1_ARATH	CPSF160	physical	21094157
THIC1_ARATH	ACAT2	physical	21094157
HMA7_ARATH	RAN1	physical	21094157
ERF80_ARATH	ERF9	physical	21094157
XPB2_ARATH	XPB2	physical	21094157
HPSE3_ARATH	GUS3	physical	21094157
GLR21_ARATH	GLR2.1	physical	21094157
RD22_ARATH	RD22	physical	21094157
2A5K_ARATH	AT5G25510	physical	21094157
SM3L2_ARATH	RAD5	physical	21094157
PER60_ARATH	RHS18	physical	21094157
DCL4_ARATH	DCL4	physical	21094157
PER59_ARATH	AT5G19890	physical	21094157
VAR3_ARATH	VAR3	physical	21094157
ATL52_ARATH	AT5G17600	physical	21094157
14335_ARATH	GRF5	physical	21094157
KIN1_ARATH	KIN1	physical	21094157
VDAC3_ARATH	VDAC3	physical	21094157
RH25_ARATH	STRS2	physical	21094157
Y5843_ARATH	AT5G08430	physical	21094157
HEM3_ARATH	HEMC	physical	21094157
EIN2_ARATH	EIN2	physical	21094157
MD37E_ARATH	HSC70-1	physical	21094157
LAX1_ARATH	LAX1	physical	21094157
ATL32_ARATH	AT4G40070	physical	21094157
CP18C_ARATH	ROC1	physical	21094157
ACA2_ARATH	ACA2	physical	21094157
ACA7_ARATH	AT2G22950	physical	21094157
IDH3_ARATH	IDH-III	physical	21094157
KCS16_ARATH	KCS16	physical	21094157
ATL13_ARATH	AT4G30400	physical	21094157
HXK1_ARATH	HXK1	physical	21094157
VP26B_ARATH	VPS26B	physical	21094157
FWA_ARATH	FWA	physical	21094157
PIP15_ARATH	PIP1;5	physical	21094157
AKT2_ARATH	KT2/3	physical	21094157
SNAG_ARATH	GSNAP	physical	21094157
KCO6_ARATH	KCO6	physical	21094157
HFA1A_ARATH	HSF1	physical	21094157
IAA14_ARATH	IAA14	physical	21094157
PLY15_ARATH	AT4G13710	physical	21094157
1A16_ARATH	ACS6	physical	21094157
SPT16_ARATH	SPT16	physical	21094157
SPT51_ARATH	GTA2	physical	21094157
FBL8_ARATH	VFB3	physical	21094157
METK2_ARATH	SAM-2	physical	21094157
METK4_ARATH	MTO3	physical	21094157
METK3_ARATH	MAT3	physical	21094157
METK1_ARATH	SAM1	physical	21094157
ECA2_ARATH	ECA2	physical	21094157
KSG8_ARATH	SK32	physical	21094157
RK1_ARATH	AT3G63490	physical	21094157
AB14C_ARATH	MRP10	physical	21094157
ARFR_ARATH	ARF18	physical	21094157
PSB1_ARATH	PBF1	physical	21094157
ATX3H_ARATH	AT3G54130	physical	21094157
PAS1_ARATH	PAS1	physical	21094157
AB20G_ARATH	AT3G53510	physical	21094157
SY122_ARATH	SYP122	physical	21094157
SUT31_ARATH	SULTR3;1	physical	21094157
NRL3_ARATH	NIT3	physical	21094157
AB18B_ARATH	PGP18	physical	21094157
2AAB_ARATH	PP2AA2	physical	21094157
CH60A_ARATH	HSP60	physical	21094157
2A5Z_ARATH	AT3G21650	physical	21094157
FUT11_ARATH	FUT11	physical	21094157
FUT12_ARATH	FUT12	physical	21094157
TONS_ARATH	TSK	physical	21094157
MSH2_ARATH	MSH2	physical	21094157
CASP_ARATH	CASP	physical	21094157
CIPK1_ARATH	CIPK1	physical	21094157
CAPP3_ARATH	PPC3	physical	21094157
AB6C_ARATH	MRP8	physical	21094157
DML2_ARATH	DML2	physical	21094157
UN933_ARATH	AT3G09470	physical	21094157
GAT15_ARATH	GATA15	physical	21094157
ISW2_ARATH	CHR11	physical	21094157
SUVR4_ARATH	SUVR4	physical	21094157
SEC_ARATH	SEC	physical	21094157
BIOB_ARATH	BIO2	physical	21094157
PLDB1_ARATH	PLDBETA1	physical	21094157
PI5K5_ARATH	PIP5K5	physical	21094157
UBP5_ARATH	UBP5	physical	21094157
SPCS2_ARATH	AT2G39960	physical	21094157
JAL23_ARATH	JAL23	physical	21094157
WRK33_ARATH	WRKY33	physical	21094157
AGT22_ARATH	AGT3	physical	21094157
NCER2_ARATH	AT2G38010	physical	21094157
ROS1_ARATH	DML1	physical	21094157
VSR5_ARATH	VSR5	physical	21094157
NFYA4_ARATH	NF-YA4	physical	21094157
CDF4_ARATH	AT2G34140	physical	21094157
THIK2_ARATH	PKT3	physical	21094157
COP1_ARATH	COP1	physical	21094157
RPT2_ARATH	RPT2	physical	21094157
BL1S1_ARATH	AT2G30330	physical	21094157
AB3G_ARATH	AT2G28070	physical	21094157
Y2433_ARATH	AT2G24330	physical	21094157
ATHB6_ARATH	HB6	physical	21094157
RER1B_ARATH	RER1B	physical	21094157
PLT4_ARATH	AT2G20780	physical	21094157
PHYB_ARATH	PHYB	physical	21094157
GGPP4_ARATH	GGPS4	physical	21094157
PER14_ARATH	AT2G18140	physical	21094157
CP19A_ARATH	ROC3	physical	21094157
BRL2_ARATH	BRL2	physical	21094157
HAC1_ARATH	HAC1	physical	21094157
AVP2_ARATH	VP2	physical	21094157
PSD3B_ARATH	AT1G75990	physical	21094157
BZR1_ARATH	BZR1	physical	21094157
IF4A3_ARATH	AT1G72730	physical	21094157
UPL2_ARATH	UPL2	physical	21094157
POT6_ARATH	KUP6	physical	21094157
COL6_ARATH	AT1G68520	physical	21094157
HSFA8_ARATH	HSFA8	physical	21094157
AB39G_ARATH	PDR11	physical	21094157
DRL13_ARATH	AT1G59780	physical	21094157
FTSH1_ARATH	FTSH1	physical	21094157
PMEI1_ARATH	PMEI1	physical	21094157
OTUBL_ARATH	AT1G28120	physical	21094157
14312_ARATH	GRF12	physical	21094157
ODPA2_ARATH	IAR4	physical	21094157
MSSP1_ARATH	TMT1	physical	21094157
SMT2_ARATH	SMT2	physical	21094157
AVPX_ARATH	VHP2;2	physical	21094157
SAP1_ARATH	AT1G12440	physical	21094157
DRL1_ARATH	AT1G12280	physical	21094157
EDR1_ARATH	EDR1	physical	21094157
ECA1_ARATH	ECA1	physical	21094157
ATL1_ARATH	AT1G04360	physical	21094157
KCS2_ARATH	KCS2	physical	21094157
PORC_ARATH	POR C	physical	21094157
KCS1_ARATH	KCS1	physical	21094157
RIBA1_ARATH	GCH	physical	21094157
DPNP1_ARATH	SAL1	physical	21094157
PHT16_ARATH	PHT1;6	physical	21094157
ATL31_ARATH	CNI1	physical	21094157
EMS1_ARATH	EMS1	physical	21094157
SAT4_ARATH	SERAT3;2	physical	21094157
SWI3D_ARATH	CHB3	physical	21094157
AKT5_ARATH	KT5	physical	21094157
AB41G_ARATH	PDR13	physical	21094157
BECN1_ARATH	ATG6	physical	21094157
AB19G_ARATH	WBC19	physical	21094157
SC24C_ARATH	CEF	physical	21094157
PROD1_ARATH	ERD5	physical	21094157
AB26G_ARATH	WBC27	physical	21094157
CD48C_ARATH	CDC48C	physical	21094157
AB1B_ARATH	ABCB1	physical	21094157
CMTA3_ARATH	SR1	physical	21094157
TMK1_ARATH	TMK1	physical	21094157
PIF3_ARATH	PIF3	physical	25501334
COP1_ARATH	COP1	physical	25501334

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of 14338_ARATH

Related Literatures of Post-Translational Modification