HPSE3_ARATH - dbPTM
HPSE3_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HPSE3_ARATH
UniProt AC Q9FZP1
Protein Name Heparanase-like protein 3
Gene Name At5g34940
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 536
Subcellular Localization Lysosome membrane
Peripheral membrane protein. Secreted.
Protein Description Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans (By similarity)..
Protein Sequence MAYRQILAIVLFLCVFQFLDCTVSSAVEENGTVFVYGRAAVGTIDEDFICATLDWWPPEKCDYGSCSWDHASILNLDLNNVILQNAIKAFAPLKIRIGGTLQDIVIYETPDSKQPCLPFTKNSSILFGYTQGCLPMRRWDELNAFFRKTGTKVIFGLNALSGRSIKSNGEAIGAWNYTNAESFIRFTAENNYTIDGWELGNELCGSGVGARVGANQYAIDTINLRNIVNRVYKNVSPMPLVIGPGGFFEVDWFTEYLNKAENSLNATTRHIYDLGPGVDEHLIEKILNPSYLDQEAKSFRSLKNIIKNSSTKAVAWVGESGGAYNSGRNLVSNAFVYSFWYLDQLGMASLYDTKTYCRQSLIGGNYGLLNTTNFTPNPDYYSALIWRQLMGRKALFTTFSGTKKIRSYTHCARQSKGITVLLMNLDNTTTVVAKVELNNSFSLRHTKHMKSYKRASSQLFGGPNGVIQREEYHLTAKDGNLHSQTMLLNGNALQVNSMGDLPPIEPIHINSTEPITIAPYSIVFVHMRNVVVPACA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
30N-linked_GlycosylationVSSAVEENGTVFVYG
CHHHHHHCCEEEEEE
37.62-
122N-linked_GlycosylationPCLPFTKNSSILFGY
CCCCCCCCCEEEEEE
37.62-
176N-linked_GlycosylationGEAIGAWNYTNAESF
CEEECCCCCCCHHHH
32.96-
191N-linked_GlycosylationIRFTAENNYTIDGWE
EEEEEECCEEECCEE
27.16-
265N-linked_GlycosylationNKAENSLNATTRHIY
HHHHHCCCCCCHHHH
34.75-
272PhosphorylationNATTRHIYDLGPGVD
CCCCHHHHHCCCCCC
10.0522074104
308N-linked_GlycosylationSLKNIIKNSSTKAVA
HHHHHHHCCCCCEEE
30.68-
370N-linked_GlycosylationGGNYGLLNTTNFTPN
CCCCCCCCCCCCCCC
50.31-
427N-linked_GlycosylationVLLMNLDNTTTVVAK
EEEEECCCCCEEEEE
42.35-
438N-linked_GlycosylationVVAKVELNNSFSLRH
EEEEEEECCCCCCCC
28.70-
510N-linked_GlycosylationPIEPIHINSTEPITI
CCCCEEECCCCCEEE
28.81-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HPSE3_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HPSE3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HPSE3_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of HPSE3_ARATH !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HPSE3_ARATH

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Related Literatures of Post-Translational Modification

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