dbPTM

AB14C_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AB14C_ARATH
UniProt AC	Q9LZJ5
Protein Name	ABC transporter C family member 14
Gene Name	ABCC14
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1539
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Pump for glutathione S-conjugates..
Protein Sequence	MRWLSSTWLSDLSCSSSSVIEPSSSLPAPIQWLRFILLSPCPQRLLSSTVDVLFLLILFFFAIQKLCSSSSSRTNGEADITKPLLGRRTRTRTTGLFKTTVVVTIVLSFCSLVLCVSAFFTTRTKLKLVDTLFWLIHAVTNVVIAVLVLHLKRFASPSHPLTLRIYWVFNFVVTTLFTVSGILHLLSDDPAAASLRADDVASFISFPLTAVLLLVSIKGSTGVVVTTSNVTAPAKSNDVVVEKSENVSLYASASFISKTFWLWMNPLLRKGYKSPLNLDQVPTLSPEHRAEKLATLFESKWPKPQENSRNPVRTTLIRCFWKEIAFTAVLAIIRLSVIYVGPVLIQSFVDFTSGKRSSPSQGYYLVLILLIAKFVEVLSTHQFNFNSQKLGMLIRSTLITALYKKGLKLTGSARQNHGVGQIVNYMAVDAQQLSDMMLQLHAIWLMPLQVAAAIVLLYNTLGPSVVTTVIGLTGIFVFILLGTKRNNRYQFSLMMNRDSRMKATNEMLNYMRVIKFQAWEDHFNERILKFREMEFGWLSKFLYSIAGNIIVLWSTPVLISALTFTTAVFLGVKLDAGTVFTTTTIFKILQEPIRTFPQSMISLSQAMISLGRLDAYMMSRELSEETVERSQGCDGNVAVEIKDGSFSWDDEDDEPAIENINFEVKKGELAAIVGTVGSGKSSLLASVLGEMHKLSGKVRVCGTTAYVAQTSWIQNGTVQDNILFGLPMNRSKYNEVLKVCCLEKDMQIMEFGDQTEIGERGINLSGGQKQRIQLARAVYQESDVYLLDDVFSAVDAHTGSDIFKKCVRGALKGKTILLVTHQVDFLHNVDRILVMRDGMIVQSGKYDELVSSGLDFGELVAAHETSMELVEAGSASATAANVPMASPITQRSISIESPRQPKSPKVHRTTSMESPRVLRTTSMESPRLSELNDESIKSFLGSNIPEDGSRLIKEEEREVGQVSFQVYKLYSTEAYGWWGMILVVFFSVAWQASLMASDYWLAYETSAKNEVSFDATVFIRVYVIIAAVSIVLVCLRAFYVTHLGLKTAQIFFKQILNSLVHAPMSFFDTTPSGRILSRASTDQTNVDIFIPFMIGLVATMYTTLLSIFIVTCQYAWPTVFFIIPLGWLNIWYRGYYLASSRELTRLDSITKAPVIHHFSESIAGVMTIRAFKKQPMFRQENVKRVNANLRMDFHNNGSNEWLGFRLELIGSWVLCISALFMVMLPSNIIKPENVGLSLSYGLSLNGVLFWAIYLSCFIENKMVSVERIKQFTDIPAEAKWEIKESRPPPNWPYKGNIRLEDVKVRYRPNTPLVLKGLTIDIKGGEKIGVVGRTGSGKSTLIQVLFRLVEPSGGKIIIDGIDICTLGLHDLRSRFGIIPQEPVLFEGTVRSNIDPTEKYSDEEIWKSLERCQLKDVVASKPEKLDSLVADNGENWSVGQRQLLCLGRVMLKRSRILFLDEATASVDSQTDAMIQKIIREDFSDCTIISIAHRIPTVMDCDRVLVIDAGKAKEYDSPVRLLERQSLFAALVQEYALRSAGI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
886	Phosphorylation	AANVPMASPITQRSI CCCCCCCCCCCCCCC	15.58	29797451
892	Phosphorylation	ASPITQRSISIESPR CCCCCCCCCCCCCCC	15.74	23776212
894	Phosphorylation	PITQRSISIESPRQP CCCCCCCCCCCCCCC	22.88	30291188
897	Phosphorylation	QRSISIESPRQPKSP CCCCCCCCCCCCCCC	24.58	27532006
903	Phosphorylation	ESPRQPKSPKVHRTT CCCCCCCCCCCCCCC	36.31	27532006
909	Phosphorylation	KSPKVHRTTSMESPR CCCCCCCCCCCCCCC	14.35	25561503
910	Phosphorylation	SPKVHRTTSMESPRV CCCCCCCCCCCCCCE	26.49	29654922
911	Phosphorylation	PKVHRTTSMESPRVL CCCCCCCCCCCCCEE	21.68	19376835
914	Phosphorylation	HRTTSMESPRVLRTT CCCCCCCCCCEEEEC	14.90	25561503
920	Phosphorylation	ESPRVLRTTSMESPR CCCCEEEECCCCCCC	21.04	25561503
921	Phosphorylation	SPRVLRTTSMESPRL CCCEEEECCCCCCCH	21.46	25561503
922	Phosphorylation	PRVLRTTSMESPRLS CCEEEECCCCCCCHH	21.68	19376835
925	Phosphorylation	LRTTSMESPRLSELN EEECCCCCCCHHHCC	13.48	25561503
929	Phosphorylation	SMESPRLSELNDESI CCCCCCHHHCCHHHH	41.12	19376835
935	Phosphorylation	LSELNDESIKSFLGS HHHCCHHHHHHHHCC	37.87	19376835
938	Phosphorylation	LNDESIKSFLGSNIP CCHHHHHHHHCCCCC	24.84	30291188
942	Phosphorylation	SIKSFLGSNIPEDGS HHHHHHCCCCCCCCC	33.46	19376835
949	Phosphorylation	SNIPEDGSRLIKEEE CCCCCCCCCHHHHHH	35.91	19376835

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AB14C_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AB14C_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AB14C_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of AB14C_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AB14C_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-894; SER-897 ANDSER-922, AND MASS SPECTROMETRY.	19376835 [Abstract]