dbPTM

PAS1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PAS1_ARATH
UniProt AC	Q7DMA9
Protein Name	Peptidyl-prolyl cis-trans isomerase PASTICCINO1
Gene Name	PAS1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	635
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type IV membrane protein . Cytoplasm . Nucleus . Relocalization from the cytoplasm into the nucleus is induced by auxin treatment and in association with NAC089.
Protein Description	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Essential protein regulating cell division, adhesion and elongation throughout the plant development and embryogenesis. Required for the spatial organization of apical meristems. Involved in the hormonal control of cell division and differentiation mediated by cytokinins and auxin. Regulates the function of NAC089 transcription factor by controlling its targeting to the nucleus upon plant cell division. Interacts with enzymes of the fatty acid elongase complex and favors the generation of very-long-chain fatty acids (VLCFAs) required for polar auxin transport and tissue patterning during plant development..
Protein Sequence	MAVGDQTEQNYLPKKKKSETEDDKRRKKIVPGSLLKAVVRPGGGDSSPVDGDQVIYHCTVRTLDGVVVESTRSESGGRGVPIRDVLGNSKMILGLLEGIPTMHKGEIAMFKMKPEMHYAEIDCPVSAPENFPKDDELHFEIELLDFSKAKIASDDLGVIKKILNEGEGWESPREPYEVKARISAKSGDGHVIFSHTEEPYFFTFGKSEVPKGLEIGIGTMARKEKAVIYVRKQYLTESPLLHIDQDLEEVHFEVELVHFIQVRDMLGDGRLIKRRIRDGRGEFPMDCPLQDSRLSVHYKGMLLNEEKTVFYDSKIDNNDQPLEFSSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAYDKFPRPPGVSEGAHVQWEIELLGFETPRDWTGLNFQSIMDEADKIRSTGNRLFKEGKFELAKAKYEKVLREFNHVNPQDEDEGKIFGDTRNMLHLNVAACLLKMGEWRKSIETCNKVLEAKPGHVKGLYRRGMAYIAGGEYDDARNDFNMMIKVDKSSEADATAALLKLKQKEQEAESKARKQFKGLFDKRPGEITEVGSEIREESKTIEEVDETKDNDDDETLEEEGATTVSTERKRKWSEKAWPFLKNVMLQIGIQLGVVLIGILIFQFVSAKFT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of PAS1_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PAS1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PAS1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PAS1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PAS1_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PAS1_ARATH

Related Literatures of Post-Translational Modification