EMS1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EMS1_ARATH
• UniProt AC: Q9LYN8
• Protein Name: Leucine-rich repeat receptor protein kinase EMS1 {ECO:0000305}
• Gene Name: EMS1 {ECO:0000303|PubMed:12154130}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1192
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Receptor with a serine/threonine-protein kinase activity required for the specification of the correct number of male archesporial initials and for the subsequent specification of tapetal and middle cell layer identities. In seeds, required for enhancing cell size and the rate of embryonic development..
• Protein Sequence: MAFLTALFLFLFFSFSSSAIVDLSSETTSLISFKRSLENPSLLSSWNVSSSASHCDWVGVTCLLGRVNSLSLPSLSLRGQIPKEISSLKNLRELCLAGNQFSGKIPPEIWNLKHLQTLDLSGNSLTGLLPRLLSELPQLLYLDLSDNHFSGSLPPSFFISLPALSSLDVSNNSLSGEIPPEIGKLSNLSNLYMGLNSFSGQIPSEIGNISLLKNFAAPSCFFNGPLPKEISKLKHLAKLDLSYNPLKCSIPKSFGELHNLSILNLVSAELIGLIPPELGNCKSLKSLMLSFNSLSGPLPLELSEIPLLTFSAERNQLSGSLPSWMGKWKVLDSLLLANNRFSGEIPHEIEDCPMLKHLSLASNLLSGSIPRELCGSGSLEAIDLSGNLLSGTIEEVFDGCSSLGELLLTNNQINGSIPEDLWKLPLMALDLDSNNFTGEIPKSLWKSTNLMEFTASYNRLEGYLPAEIGNAASLKRLVLSDNQLTGEIPREIGKLTSLSVLNLNANMFQGKIPVELGDCTSLTTLDLGSNNLQGQIPDKITALAQLQCLVLSYNNLSGSIPSKPSAYFHQIEMPDLSFLQHHGIFDLSYNRLSGPIPEELGECLVLVEISLSNNHLSGEIPASLSRLTNLTILDLSGNALTGSIPKEMGNSLKLQGLNLANNQLNGHIPESFGLLGSLVKLNLTKNKLDGPVPASLGNLKELTHMDLSFNNLSGELSSELSTMEKLVGLYIEQNKFTGEIPSELGNLTQLEYLDVSENLLSGEIPTKICGLPNLEFLNLAKNNLRGEVPSDGVCQDPSKALLSGNKELCGRVVGSDCKIEGTKLRSAWGIAGLMLGFTIIVFVFVFSLRRWAMTKRVKQRDDPERMEESRLKGFVDQNLYFLSGSRSREPLSINIAMFEQPLLKVRLGDIVEATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSEAKTQGNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTGMLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFGLARLISACESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
47	N-linked_Glycosylation	PSLLSSWNVSSSASH CHHHHCCCCCCCHHC		-
171	N-linked_Glycosylation	LSSLDVSNNSLSGEI CCCCCCCCCCCCCCC		-
187	N-linked_Glycosylation	PEIGKLSNLSNLYMG HHHHHHCCHHHHHHH		-
208	N-linked_Glycosylation	QIPSEIGNISLLKNF CCCHHCCCHHHHHCC		-
259	N-linked_Glycosylation	KSFGELHNLSILNLV CCHHHHCCCHHHHHH		-
414	N-linked_Glycosylation	LLTNNQINGSIPEDL HHHCCCCCCCCCHHH		-
435	N-linked_Glycosylation	ALDLDSNNFTGEIPK EEECCCCCCCCCCCH		-
555	N-linked_Glycosylation	CLVLSYNNLSGSIPS HHHHCCCCCCCCCCC		-
629	N-linked_Glycosylation	ASLSRLTNLTILDLS CHHHHHCCCEEEECC		-
682	N-linked_Glycosylation	LGSLVKLNLTKNKLD HHHHHHCCCCCCCCC		-
695	Phosphorylation	LDGPVPASLGNLKEL CCCCCCCCCCCHHHC		19880383
711	N-linked_Glycosylation	HMDLSFNNLSGELSS CCCCCCCCCCHHHHH		-
746	N-linked_Glycosylation	EIPSELGNLTQLEYL CCCHHHCCCEEEEEE		-
914	Phosphorylation	LGDIVEATDHFSKKN HHHHHHHCCCCCCCC		-
990	Phosphorylation	SEEKLLVYEYMVNGS CHHHHHEEEHHHCCC		-
1085	Phosphorylation	VIAGTFGYIPPEYGQ HHHHCCCCCCHHHCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EMS1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EMS1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EMS1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.