AB3G_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AB3G_ARATH
• UniProt AC: Q9ZUU9
• Protein Name: ABC transporter G family member 3
• Gene Name: ABCG3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 730
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Sequence: MEEIQSQSDLYRSSSSSASSPTSRVPSSHFFYVRKPGSLRQPISFEDSPEWEDTPDVDLRMEDEAGGGDSINDATTTPVSPSLSKMNSGSMASPPVPEGGAGTGVVRKIAGASIAWKDLTVTMKGKRKYSDKVVKSSNGYAFPGTMTVIMGPAKSGKSTLLRALAGRLPPSAKMYGEVFVNGSKSHMPYGSYGFVERETQLIGSLTVREFLYYSALLQLPGFLFQKRSVVEDAIQAMSLSDYANKLIGGHCYMKGLRSGERRRVSIARELVMRPHILFIDEPLYHLDSVSALLMMVTLKKLASMGCTLVFTIYQSSTEVFGLFDRICLLSNGNTLFFGETLACLQHFSNAGFPCPIMQSPSDHFLRAINTDFDRIIAMCKNWQDDNGDFSAVNMDTAVAIRTLEATYKSSADADSVEAMIIKLTEREGTQLKSKGKAGAATRVAVLTWRSLLVMSREWKYYWLRLILYMILTLSIGTLYSGLGHSLSSVATRVAAVFVFVSFASLLGIAGIPSLLKEIKIYRSEASNQHSGAFVFLLGQFLGSIPFLFLMSISSSLVFYFMVGLRDDFSLLMYFVLNFFMCLLVNEGLMLFIACIWRDVYWSTLTLISVHVIMMLAAGHFRIRTALPKPVWTYPFAYISFHTYSIEGLLENEYLGEVFAVGEVRSISGYQAIQGNYQISPDTNAKWRNMLVLLAMAFGYRLLVYVLLRFGLNKNVSGRLLLSHKKNNSSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	SPTSRVPSSHFFYVR CCCCCCCCCCEEEEC	33.32	29654922
44	Phosphorylation	GSLRQPISFEDSPEW CCCCCCCCCCCCCCC	29.30	30407730
48	Phosphorylation	QPISFEDSPEWEDTP CCCCCCCCCCCCCCC	19.95	30291188
54	Phosphorylation	DSPEWEDTPDVDLRM CCCCCCCCCCCEEEE	15.18	23110452
75	Phosphorylation	GDSINDATTTPVSPS CCCCCCCCCCCCCCC	33.78	30407730
76	Phosphorylation	DSINDATTTPVSPSL CCCCCCCCCCCCCCH	30.72	30407730
77	Phosphorylation	SINDATTTPVSPSLS CCCCCCCCCCCCCHH	19.82	30407730
80	Phosphorylation	DATTTPVSPSLSKMN CCCCCCCCCCHHCCC	15.24	30291188
82	Phosphorylation	TTTPVSPSLSKMNSG CCCCCCCCHHCCCCC	37.46	17317660
84	Phosphorylation	TPVSPSLSKMNSGSM CCCCCCHHCCCCCCC	33.91	30407730
88	Phosphorylation	PSLSKMNSGSMASPP CCHHCCCCCCCCCCC	28.84	15308754
90	Phosphorylation	LSKMNSGSMASPPVP HHCCCCCCCCCCCCC	15.82	15308754
93	Phosphorylation	MNSGSMASPPVPEGG CCCCCCCCCCCCCCC	22.54	15308754

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AB3G_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AB3G_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AB3G_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDPK1_ARATH	CPK1	physical	22737156
CNG10_ARATH	CNGC10	physical	22737156

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomics of early elicitor signaling inArabidopsis.";
Benschop J.J., Mohammed S., O'Flaherty M., Heck A.J.R., Slijper M.,Menke F.L.H.;
Mol. Cell. Proteomics 6:1198-1214(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-93, AND MASSSPECTROMETRY.
PubMed: 17317660

"Phosphoproteomics of the Arabidopsis plasma membrane and a newphosphorylation site database.";
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
Plant Cell 16:2394-2405(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-93, AND MASSSPECTROMETRY.
PubMed: 15308754

"Large-scale analysis of in vivo phosphorylated membrane proteins byimmobilized metal ion affinity chromatography and mass spectrometry.";
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
Mol. Cell. Proteomics 2:1234-1243(2003).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-88; SER-90 AND SER-93,AND MASS SPECTROMETRY.
PubMed: 14506206