| UniProt ID | GLR21_ARATH | |
|---|---|---|
| UniProt AC | O04660 | |
| Protein Name | Glutamate receptor 2.1 | |
| Gene Name | GLR2.1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 901 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. |
|
| Protein Description | Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.. | |
| Protein Sequence | MKRENNLVLSLLFFVIVFLMQVGEAQNRITNVNVGIVNDIGTAYSNMTLLCINMSLSDFYSSHPETQTRLVTTVVDSKNDVVTAAAAALDLITNKEVKAILGPWTSMQAQFMIEMGQKSQVPIVTYSATSPSLASIRSQYFFRATYDDSSQVHAIKEIIKLFGWREVAPVYVDDTFGEGIMPRLTDVLQEINVRIPYRTVISPNATDDEISVELLRMMTLPTRVFVVHLVELLASRFFAKATEIGLMKQGYVWILTNTITDVLSIMNETEIETMQGVLGVKTYVPRSKELENFRSRWTKRFPISDLNVYGLWAYDATTALALAIEEAGTSNLTFVKMDAKRNVSELQGLGVSQYGPKLLQTLSRVRFQGLAGDFQFINGELQPSVFEIVNVNGQGGRTIGFWMKEYGLFKNVDQKPASKTTFSSWQDRLRPIIWPGDTTSVPKGWEIPTNGKRLQIGVPVNNTFQQFVKATRDPITNSTIFSGFSIDYFEAVIQAIPYDISYDFIPFQDGGYDALVYQVYLGKYDAVVADTTISSNRSMYVDFSLPYTPSGVGLVVPVKDSVRRSSTIFLMPLTLALWLISLLSFFIIGLVVWVLEHRVNPDFDGPGQYQLSTIFWFSFSIMVFAPRERVLSFWARVVVIIWYFLVLVLTQSYTASLASLLTTQHLHPTVTNINSLLAKGESVGYQSSFILGRLRDSGFSEASLVSYGSPEHCDALLSKGQAEGGVSAVLMEVPYVRIFLGQYCNKYKMVQTPFKVDGLGFVFPIGSPLVADISRAILKVEESNKANQLENAWFKPIDESCPDPLTNPDPNPSVSFRQLGFDSFWVLFLVAAIVCTMALLKFVYQFLKENPNQRNLRVLWEKFNEPDQKSYIKDVTKCQCSSGQGMPKNGQEGANAVNNGN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 46 | N-linked_Glycosylation | DIGTAYSNMTLLCIN CCCHHCCCCEEEEEE | 18.12 | - | |
| 53 | N-linked_Glycosylation | NMTLLCINMSLSDFY CCEEEEEECCHHHHH | 17.00 | - | |
| 119 | Phosphorylation | MIEMGQKSQVPIVTY HHHCCCCCCCCEEEE | 28.64 | 19880383 | |
| 125 | Phosphorylation | KSQVPIVTYSATSPS CCCCCEEEEECCCHH | 16.69 | 19880383 | |
| 127 | Phosphorylation | QVPIVTYSATSPSLA CCCEEEEECCCHHHH | 18.72 | 19880383 | |
| 204 | N-linked_Glycosylation | YRTVISPNATDDEIS CEEEECCCCCCCHHH | 48.99 | - | |
| 267 | N-linked_Glycosylation | TDVLSIMNETEIETM HHHHHHCCHHHHHHH | 51.90 | - | |
| 331 | N-linked_Glycosylation | IEEAGTSNLTFVKMD HHHHCCCCCEEEECC | 42.83 | - | |
| 342 | N-linked_Glycosylation | VKMDAKRNVSELQGL EECCCCCCHHHHCCC | 40.74 | - | |
| 461 | N-linked_Glycosylation | LQIGVPVNNTFQQFV EEEECCCCCHHHHHH | 35.44 | - | |
| 477 | N-linked_Glycosylation | ATRDPITNSTIFSGF HHCCCCCCCCCCCCC | 37.56 | - | |
| 536 | N-linked_Glycosylation | ADTTISSNRSMYVDF EECEECCCCCEEEEE | 33.00 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GLR21_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GLR21_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GLR21_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| GLR21_ARATH | GLR2.1 | physical | 24300102 | |
| GLR11_ARATH | GLR1.1 | physical | 24300102 | |
| GLR14_ARATH | GLR1.4 | physical | 24300102 | |
| GLR27_ARATH | GLR2.7 | physical | 24300102 | |
| GLR31_ARATH | GLR2 | physical | 24300102 | |
| GLR32_ARATH | GLUR2 | physical | 24300102 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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