GLR27_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLR27_ARATH
• UniProt AC: Q8LGN0
• Protein Name: Glutamate receptor 2.7
• Gene Name: GLR2.7
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 952
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells..
• Protein Sequence: MKVMNPRKTNNTFMYYFVLFVCGFVLMEGCLGQNQTTEIKVGVVLDLHTSFSKLCLTSINISLSDFYKYHSDYTTRLAIHIRDSMEDVVQASSAALDLIKNEQVSAIIGPRTSMQAEFMIRLADKSQVPTITFSATCPLLTSINSPYFVRATLDDSSQVKAIAAIVKSFGWRNVVAIYVDNEFGEGILPLLTDALQDVQAFVVNRCLIPQEANDDQILKELYKLMTMQTRVFVVHMPPTLGFRFFQKAREIGMMEEGYVWLLTDGVMNLLKSNERGSSLENMQGVLGVRSHIPKSKKLKNFRLRWEKMFPKKGNDEEMNIFALRAYDSITALAMAVEKTNIKSLRYDHPIASGNNKTNLGTLGVSRYGPSLLKALSNVRFNGLAGEFELINGQLESSVFDVINIIGSEERIIGLWRPSNGIVNAKSKNTTSVLGERLGPVIWPGKSKDVPKGWQIPTNGKMLRVGIPVKKGFLEFVDAKIDPISNAMTPTGYCIEIFEAVLKKLPYSVIPKYIAFLSPDENYDEMVYQVYTGAYDAVVGDVTIVANRSLYVDFTLPYTESGVSMMVPLKDNKNTWVFLRPWSLDLWVTTACFFVFIGFIVWILEHRVNTDFRGPPHHQIGTSFWFAFSTMNFAHREKVVSNLARFVVLVWCFVVLVLIQSYTANLTSFFTVKLLQPTVTNWKDLIKFNKNIGYQRGTFVRELLKSQGFDESQLKPFGSAVECDELFSNGTITASFDEVAYIKVILSQNSSKYTMVEPSFKTAGFGFVFPKKSPLTDDVSRAILNVTQGEEMQHIENKWFKKPNNCPDLNTSLSSNHLSLSSFWGLFLIAGIASFLALLIFVANFLYEHKHTLFDDSENSFRGKLKFLVRNFDEKDIKSHMFKENAVHNVSSPITQGSSSPLTDQSTPLPRSPEQYRELELRRVSSISSGELFTTQSEQVEDEESAIIQCEGE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	N-linked_Glycosylation	MEGCLGQNQTTEIKV HHCCCCCCCCCEEEE	39.09	-
60	N-linked_Glycosylation	KLCLTSINISLSDFY HHHHHHCEEEHHHHH	19.98	-
355	N-linked_Glycosylation	HPIASGNNKTNLGTL CCCCCCCCCCCCCCC	56.93	-
428	N-linked_Glycosylation	IVNAKSKNTTSVLGE CCCCCCCCCCCCCHH	56.53	-
546	N-linked_Glycosylation	GDVTIVANRSLYVDF EEEEEEECCEEEEEE	24.15	-
664	N-linked_Glycosylation	LIQSYTANLTSFFTV HHHHHCCCCCHHEEE	35.73	-
728	N-linked_Glycosylation	ECDELFSNGTITASF ECHHHHCCCEEEEEC	44.27	-
746	Phosphorylation	AYIKVILSQNSSKYT EEEEEEECCCCCCEE	19.05	24894044
748	N-linked_Glycosylation	IKVILSQNSSKYTMV EEEEECCCCCCEEEE	44.89	-
784	N-linked_Glycosylation	DVSRAILNVTQGEEM HHHHHHHHCCCCHHH	28.77	-
809	N-linked_Glycosylation	PNNCPDLNTSLSSNH CCCCCCCCCCCCCCC	34.69	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLR27_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLR27_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLR27_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GLR27_ARATH	GLR2.7	physical	24300102
GLR11_ARATH	GLR1.1	physical	24300102
GLR14_ARATH	GLR1.4	physical	24300102
GLR29_ARATH	GLR2.9	physical	24300102

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.