DPNP1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DPNP1_ARATH
• UniProt AC: Q42546
• Protein Name: SAL1 phosphatase
• Gene Name: SAL1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 353
• Protein Description: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate (IP3) turnover. Is also involved in salt tolerance. Acts as a suppressor of virus- and transgene-induced silencing..
• Protein Sequence: MAYEKELDAAKKAASLAARLCQKVQKALLQSDVQSKSDKSPVTVADYGSQAVVSLVLEKELSSEPFSLVAEEDSGDLRKDGSQDTLERITKLVNDTLATEESFNGSTLSTDDLLRAIDCGTSEGGPNGRHWVLDPIDGTKGFLRGDQYAVALGLLEEGKVVLGVLACPNLPLASIAGNNKNKSSSDEIGCLFFATIGSGTYMQLLDSKSSPVKVQVSSVENPEEASFFESFEGAHSLHDLSSSIANKLGVKAPPVRIDSQAKYGALSRGDGAIYLRFPHKGYREKIWDHVAGAIVVTEAGGIVTDAAGKPLDFSKGKYLDLDTGIIVANEKLMPLLLKAVRDSIAEQEKASAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	QSDVQSKSDKSPVTV CCHHCCCCCCCCEEH	56.36	23776212
40	Phosphorylation	VQSKSDKSPVTVADY HCCCCCCCCEEHHHH	29.59	23776212
43	Phosphorylation	KSDKSPVTVADYGSQ CCCCCCEEHHHHCHH	17.23	23776212
47	Phosphorylation	SPVTVADYGSQAVVS CCEEHHHHCHHHHHH	14.67	23776212
49	Phosphorylation	VTVADYGSQAVVSLV EEHHHHCHHHHHHHH	14.56	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DPNP1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DPNP1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DPNP1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of DPNP1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.