dbPTM

RAD17_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RAD17_ARATH
UniProt AC	Q9MBA3
Protein Name	Cell cycle checkpoint protein RAD17 {ECO:0000303\|Ref.1}
Gene Name	RAD17 {ECO:0000303\|Ref.1}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	599
Subcellular Localization	Nucleus .
Protein Description	Seems to be involved in regulation of DNA repair correlated to non-homologous double strand breaks (DSBs) repair. In vitro, involved in rapid but not in slow DSB repair mechanism. Required for effective immune responses that involve activation of DNA damage responses. [PubMed: 24207055]
Protein Sequence	MLKKKLSLEDEDDDRSYNLRSSRSNAKSKPRSSAGTATNPRASKRARLSGASATQEDSSLVDKIRLSFEDFDEALSGFKVSSGYERSKNTDLWVDKYRPRTLEELSVHKKKVDEVKLWFQESLDFLKNGLRNNVLLVTGQAGVGKSATIHLITSILGVTVHEWNAPIPTIWQEHVHNTSSGLKYTSKLDEFENFVESTRKYGVMASSSTDGIKAPVVLLIDDLPLANGRHAFERLQNCLLLLVKSTQIPTVILITDHNNADSSDQTARRMEDTQSSLERAGALKVAFNPITKNSIKKVLQRICREEHCKVTTMEIDQMATASGGDIRHAITSLQLFSVKPELNHTKIKSPRPGMEDNYHGNEQTMYSGLDSGISSCFGRDETLSLFHALGKFLHNKRETDNVIISECSSSLVHDEFARLPLKMDAPEKVLSQAHGQAGRVVDFLHENVLDFVSDGAIEDAWCVSSYLADADLLLADIRGKMSGHNNTEDVPQSAGASVAVRGVLYGNKQPCSSRWHVIRKPKLWQVEQSSIQTKKNLREQRNISYEGSRVADISVMATEYSPVLKWLSYRASPDAFPGMGEETDEEDSDISEDDEIQDW

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
311	Phosphorylation	REEHCKVTTMEIDQM HHHCCEEEEEEHHHH	13.11	19880383
312	Phosphorylation	EEHCKVTTMEIDQMA HHCCEEEEEEHHHHH	18.78	19880383
320	Phosphorylation	MEIDQMATASGGDIR EEHHHHHHCCCCCHH	18.93	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RAD17_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RAD17_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RAD17_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RAD17_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RAD17_ARATH

Related Literatures of Post-Translational Modification