ECA2_ARATH - dbPTM
ECA2_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ECA2_ARATH
UniProt AC O23087
Protein Name Calcium-transporting ATPase 2, endoplasmic reticulum-type
Gene Name ECA2
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 1054
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to an endomembrane compartment..
Protein Sequence MEEEKSFSAWSWSVEQCLKEYKTRLDKGLTSEDVQIRRQKYGFNELAKEKGKPLWHLVLEQFDDTLVKILLGAAFISFVLAFLGEEHGSGSGFEAFVEPFVIVLILILNAVVGVWQESNAEKALEALKEMQCESAKVLRDGNVLPNLPARELVPGDIVELNVGDKVPADMRVSGLKTSTLRVEQSSLTGEAMPVLKGANLVVMDDCELQGKENMVFAGTTVVNGSCVCIVTSIGMDTEIGKIQRQIHEASLEESETPLKKKLDEFGSRLTTAICIVCVLVWMINYKNFVSWDVVDGYKPVNIKFSFEKCTYYFKIAVALAVAAIPEGLPAVITTCLALGTRKMAQKNAIVRKLPSVETLGCTTVICSDKTGTLTTNQMSATEFFTLGGKTTTTRVFSVSGTTYDPKDGGIVDWGCNNMDANLQAVAEICSICNDAGVFYEGKLFRATGLPTEAALKVLVEKMGIPEKKNSENIEEVTNFSDNGSSVKLACCDWWNKRSKKVATLEFDRVRKSMSVIVSEPNGQNRLLVKGAAESILERSSFAQLADGSLVALDESSREVILKKHSEMTSKGLRCLGLAYKDELGEFSDYSSEEHPSHKKLLDPSSYSNIETNLIFVGVVGLRDPPREEVGRAIEDCRDAGIRVMVITGDNKSTAEAICCEIRLFSENEDLSQSSFTGKEFMSLPASRRSEILSKSGGKVFSRAEPRHKQEIVRMLKEMGEIVAMTGDGVNDAPALKLADIGIAMGITGTEVAKEASDMVLADDNFSTIVSAVAEGRSIYNNMKAFIRYMISSNVGEVISIFLTAALGIPECMIPVQLLWVNLVTDGPPATALGFNPADIDIMKKPPRKSDDCLIDSWVLIRYLVIGSYVGVATVGIFVLWYTQASFLGISLISDGHTLVSFTQLQNWSECSSWGTNFTATPYTVAGGLRTIAFENNPCDYFTLGKVKPMTLSLTVLVAIEMFNSLNALSEDNSLLTMPPWRNPWLLVAMTVSFALHCVILYVPFLANVFGIVPLSFREWFVVILVSFPVILIDEALKFIGRCRRTRIKKKIKTM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ECA2_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ECA2_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ECA2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ECA2_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MLO4_ARATHMLO4physical
22737156
CNG10_ARATHCNGC10physical
22737156
DNJ21_ARATHATERDJ2Aphysical
22737156

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ECA2_ARATH

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Related Literatures of Post-Translational Modification

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