dbPTM

14312_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	14312_ARATH
UniProt AC	Q9C5W6
Protein Name	14-3-3-like protein GF14 iota {ECO:0000303\|PubMed:11553742}
Gene Name	GRF12 {ECO:0000303\|PubMed:11553742}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	268
Subcellular Localization	Nucleus . Cytoplasm . Translocates from the cytosol to the nucleus when phosphorylated.
Protein Description	Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes..
Protein Sequence	MSSSGSDKERETFVYMAKLSEQAERYDEMVETMKKVARVNSELTVEERNLLSVGYKNVIGARRASWRIMSSIEQKEESKGNESNVKQIKGYRQKVEDELANICQDILTIIDQHLIPHATSGEATVFYYKMKGDYYRYLAEFKTEQERKEAAEQSLKGYEAATQAASTELPSTHPIRLGLALNFSVFYYEIMNSPERACHLAKQAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDLPEDGGEDNIKTEESKQEQAKPADATEN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	KKVARVNSELTVEER HHHHHHCCCCCHHHH	31.00	19880383
70	Phosphorylation	RASWRIMSSIEQKEE HHHHHHHHHHHHHHH	26.28	-
154	Phosphorylation	RKEAAEQSLKGYEAA HHHHHHHHHHHHHHH	24.45	24894044
193	Phosphorylation	FYYEIMNSPERACHL HHHHHHCCHHHHHHH	15.68	-
214	Phosphorylation	EAIAELDTLSEESYK HHHHHHHCCCHHHHC	44.82	-
239	Phosphorylation	DNLTLWTSDLPEDGG CCCEEEECCCCCCCC	26.10	22631563
255	Phosphorylation	DNIKTEESKQEQAKP CCCCCHHHHHHHCCC	33.15	22631563

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of 14312_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of 14312_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of 14312_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
GDU2_ARATH	GDU2	physical	22737156
NUDT7_ARATH	NUDT7	physical	19448856

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of 14312_ARATH

Related Literatures of Post-Translational Modification