dbPTM

HFA1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HFA1A_ARATH
UniProt AC	P41151
Protein Name	Heat stress transcription factor A-1a
Gene Name	HSFA1A
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	495
Subcellular Localization	Cytoplasm . Nucleus.
Protein Description	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE)..
Protein Sequence	MFVNFKYFSFFIRTKMDGVTGGGTNIGEAVTAPPPRNPHPATLLNANSLPPPFLSKTYDMVEDPATDAIVSWSPTNNSFIVWDPPEFSRDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDRWEFANEGFLRGQKHLLKKISRRKSVQGHGSSSSNPQSQQLSQGQGSMAALSSCVEVGKFGLEEEVEQLKRDKNVLMQELVKLRQQQQTTDNKLQVLVKHLQVMEQRQQQIMSFLAKAVQNPTFLSQFIQKQTDSNMHVTEANKKRRLREDSTAATESNSHSHSLEASDGQIVKYQPLRNDSMMWNMMKTDDKYPFLDGFSSPNQVSGVTLQEVLPITSGQSQAYASVPSGQPLSYLPSTSTSLPDTIMPETSQIPQLTRESINDFPTENFMDTEKNVPEAFISPSPFLDGGSVPIQLEGIPEDPEIDELMSNFEFLEEYMPESPVFGDATTLENNNNNNNNNNNNNNNNNNNNTNGRHMDKLIEELGLLTSETEH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
14	Phosphorylation	YFSFFIRTKMDGVTG EEEEEEEECCCCCCC	26.38	19880383
20	Phosphorylation	RTKMDGVTGGGTNIG EECCCCCCCCCCCCC	35.32	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HFA1A_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HFA1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HFA1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDKA1_ARATH	CDC2	physical	9306693
PPP7_ARATH	PP7	physical	17238907
TBP2_ARATH	TBP2	physical	15604728
TF2B_HUMAN	GTF2B	physical	15604728
MD37C_ARATH	HSP70	physical	11807141
MD37E_ARATH	HSC70-1	physical	11807141
TRP4_ARATH	TBP1	physical	9801140
TBP2_ARATH	TBP2	physical	9801140
HFA1B_ARATH	HSF3	physical	19945192
HFA1A_ARATH	HSF1	physical	19945192
HFA1A_ARATH	HSF1	physical	20388662
HFA1B_ARATH	HSF3	physical	20388662
LCBK1_ARATH	LCBK1	physical	18466301
LCKB2_ARATH	AT2G46090	physical	18466301
CAMK1_ARATH	CRK1	physical	18466301

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HFA1A_ARATH

Related Literatures of Post-Translational Modification