SWI3D_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SWI3D_ARATH
• UniProt AC: Q8VY05
• Protein Name: SWI/SNF complex subunit SWI3D
• Gene Name: SWI3D
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 985
• Subcellular Localization: Nucleus .
• Protein Description: Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors..
• Protein Sequence: MEEKRRDSAGTLAFAGSSGDSPASEPMPAPRRRGGGLKRKANALGGSNFFSSAPSKRMLTREKAMLASFSPVHNGPLTRARQAPSIMPSAADGVKSEVLNVAVGADGEKPKEEEERNKAIREWEALEAKIEADFEAIRSRDSNVHVVPNHCGWFSWEKIHPLEERSLPSFFNGKLEGRTSEVYREIRNWIMGKFHSNPNIQIELKDLTELEVGDSEAKQEVMEFLDYWGLINFHPFPPTDTGSTASDHDDLGDKESLLNSLYRFQVDEACPPLVHKPRFTAQATPSGLFPDPMAADELLKQEGPAVEYHCNSCSADCSRKRYHCPKQADFDLCTECFNSGKFSSDMSSSDFILMEPAEAPGVGSGKWTDQETLLLLEALEIFKENWNEIAEHVATKTKAQCMLHFLQMPIEDAFLDQIDYKDPISKDTTDLAVSKDDNSVLKDAPEEAENKKRVDEDETMKEVPEPEDGNEEKVSQESSKPGDASEETNEMEAEQKTPKLETAIEERCKDEADENIALKALTEAFEDVGHSSTPEASFSFADLGNPVMGLAAFLVRLAGSDVATASARASIKSLHSNSGMLLATRHCYILEDPPDNKKDPTKSKSCSADAEGNDDNSHKDDQPEEKSKKAEEVSLNSDDREMPDTDTGKETQDSVSEEKQPGSRTENSTTKLDAVQEKRSSKPVTTDNSEKPVDIICPSQDKCSGKELQEPLKDGNKLSSENKDASQSTVSQSAADASQPEASRDVEMKDTLQSEKDPEDVVKTVGEKVQLAKEEGANDVLSTPDKSVSQQPIGSASAPENGTAGGNPNIEGKKEKDICEGTKDKYNIEKLKRAAISAISAAAVKAKNLAKQEEDQIRQLSGSLIEKQLHKLEAKLSIFNEAESLTMRVREQLERSRQRLYHERAQIIAARLGVPPSMSSKASLPTNRIAANFANVAQRPPMGMAFPRPPMPRPPGFPVPGSFVAATTMTGSSDPSPGSDNVSSV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
497	Phosphorylation	EMEAEQKTPKLETAI HHHHHHHCCHHHHHH	25.91	24894044
605	Phosphorylation	KDPTKSKSCSADAEG CCCCCCCCCCCCCCC	22.01	23776212
607	Phosphorylation	PTKSKSCSADAEGND CCCCCCCCCCCCCCC	35.95	23776212
617	Phosphorylation	AEGNDDNSHKDDQPE CCCCCCCCCCCCCHH	38.62	30407730
728	Phosphorylation	ENKDASQSTVSQSAA CCCCCCHHHHHHHHH	28.42	25561503
729	Phosphorylation	NKDASQSTVSQSAAD CCCCCHHHHHHHHHH	19.28	25561503
731	Phosphorylation	DASQSTVSQSAADAS CCCHHHHHHHHHHHC	20.64	25561503
733	Phosphorylation	SQSTVSQSAADASQP CHHHHHHHHHHHCCC	20.23	25561503
738	Phosphorylation	SQSAADASQPEASRD HHHHHHHCCCHHHCC	46.98	25561503
782	Phosphorylation	EGANDVLSTPDKSVS CCCCCCCCCCCCCCC	37.43	30407730
783	Phosphorylation	GANDVLSTPDKSVSQ CCCCCCCCCCCCCCC	31.20	23111157
837	Phosphorylation	KLKRAAISAISAAAV HHHHHHHHHHHHHHH	18.15	24894044
840	Phosphorylation	RAAISAISAAAVKAK HHHHHHHHHHHHHHH	16.15	24894044
896	Phosphorylation	VREQLERSRQRLYHE HHHHHHHHHHHHHHH	24.32	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SWI3D_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SWI3D_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SWI3D_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SWI3B_ARATH	SWI3B	physical	16055636

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.