dbPTM

SKIP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SKIP2_ARATH
UniProt AC	Q9FE83
Protein Name	F-box protein SKIP2
Gene Name	SKIP2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	527
Subcellular Localization	Nucleus.
Protein Description	Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins..
Protein Sequence	MGQAPSSTAESNGRELDLRLWSPVIVAGGESMAVGNVVDRDFTGDLPDECLAHVFQFLGAGDRKRCSLVCKRWLLVDGQSRHRLSLDAKDEISSFLTSMFNRFDSVTKLALRCDRKSVSLSDEALAMISVRCLNLTRVKLRGCREITDLGMEDFAKNCKNLKKLSVGSCNFGAKGVNAMLEHCKLLEELSVKRLRGIHEAAELIHLPDDASSSSLRSICLKELVNGQVFEPLLATTRTLKTLKIIRCLGDWDKVLQMIANGKSSLSEIHLERLQVSDIGLSAISKCSNVETLHIVKTPECSNFGLIYVAERCKLLRKLHIDGWRTNRIGDEGLLSVAKHCLNLQELVLIGVNATHMSLAAIASNCEKLERLALCGSGTIGDTEIACIARKCGALRKFCIKGCPVSDRGIEALAVGCPNLVKLKVKKCKVVTGEIGDWLREQRRTLVVSMDGDETEAVVVVDGEVETVVEEPRVAQAGGIVAEIGSSNGGGGSRLAMIRSKLGFLAGRNLVTCTFRRWSHNDNASSST

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
105	Phosphorylation	SMFNRFDSVTKLALR HHHHHCCHHHHHHHH	29.04	24243849
107	Phosphorylation	FNRFDSVTKLALRCD HHHCCHHHHHHHHCC	25.05	19880383
190	Phosphorylation	CKLLEELSVKRLRGI HHHHHHHCHHHHCCH	28.95	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SKIP2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SKIP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SKIP2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SKIP2_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SKIP2_ARATH

Related Literatures of Post-Translational Modification