| UniProt ID | CIPK1_ARATH | |
|---|---|---|
| UniProt AC | Q8RWC9 | |
| Protein Name | CBL-interacting serine/threonine-protein kinase 1 | |
| Gene Name | CIPK1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 444 | |
| Subcellular Localization | ||
| Protein Description | CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.. | |
| Protein Sequence | MVRRQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTRITVVGIKASEWFKLEYIPSIPDDDDEEEVDTDDDAFSIQELGSEEGKGSDSPTIINAFQLIGMSSFLDLSGFFEQENVSERRIRFTSNSSAKDLLEKIETAVTEMGFSVQKKHAKLRVKQEERNQKGQVGLSVTAEVFEIKPSLNVVELRKSYGDSCLYRQLYERLLKDVGTSSPEQEIVT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 165 | Phosphorylation | KITDFGLSALPQHFR EECCCCHHCCCHHHC | 28.30 | - | |
| 179 | Phosphorylation | RDDGLLHTTCGSPNY CCCCCCCCCCCCCCC | 24.61 | - | |
| 350 | Phosphorylation | ERRIRFTSNSSAKDL CCCEEEECCCCHHHH | 31.81 | 25561503 | |
| 352 | Phosphorylation | RIRFTSNSSAKDLLE CEEEECCCCHHHHHH | 31.29 | 25561503 | |
| 353 | Phosphorylation | IRFTSNSSAKDLLEK EEEECCCCHHHHHHH | 43.52 | 25561503 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CIPK1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CIPK1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CIPK1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CNBL1_ARATH | CBL1 | physical | 11115898 | |
| CNBL3_ARATH | CBL3 | physical | 11115898 | |
| CNBL2_ARATH | CBL2 | physical | 11230129 | |
| CNBL1_ARATH | CBL1 | physical | 11230129 | |
| CNBL3_ARATH | CBL3 | physical | 11230129 | |
| CNBL4_ARATH | SOS3 | physical | 11230129 | |
| CNBL5_ARATH | CBL5 | physical | 11230129 | |
| CNBL6_ARATH | CBL6 | physical | 11230129 | |
| CNBL1_ARATH | CBL1 | physical | 17092313 | |
| CNBL9_ARATH | CBL9 | physical | 17092313 | |
| CDPK1_ARATH | CPK1 | physical | 22737156 | |
| CIPK1_ARATH | CIPK1 | physical | 22253446 | |
| CNBL1_ARATH | CBL1 | physical | 22253446 | |
| CNBL1_ARATH | CBL1 | physical | 18643980 | |
| CNBL9_ARATH | CBL9 | physical | 18643980 | |
| CNBL4_ARATH | SOS3 | physical | 24970010 | |
| CNBL7_ORYSJ | Os02g0291000 | physical | 24970010 | |
| CNBL4_ORYSJ | Os05g0534400 | physical | 24970010 | |
| CNBL5_ORYSJ | Os01g0598200 | physical | 24970010 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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