VTI11_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VTI11_ARATH
• UniProt AC: Q9SEL6
• Protein Name: Vesicle transport v-SNARE 11
• Gene Name: VTI11
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 221
• Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein. Vacuole membrane ; Single-pass type IV membrane protein .
• Protein Description: May function as a v-SNARE responsible for targeting AtELP-containing vesicles from the trans-Golgi network (TGN) to the prevacuolar compartment (PVC). May be also involved in retrograde traffic to the cis-Golgi (By similarity). Promotes the formation of vacuolar membrane 'bulbs'. Required for amyloplast sedimentation in the endodermis during shoot gravitropism, which are thus acting as statoliths. Expression in the endodermis is essential for the shoot gravitropic response, whereas expression in other tissues may be responsible for the correct stem and leaf shape..
• Protein Sequence: MSDVFDGYERQYCELSASLSKKCSSAISLDGEQKKQKLSEIKSGLENAEVLIRKMDLEARTLPPNLKSSLLVKLREFKSDLNNFKTEVKRITSGQLNAAARDELLEAGMADTKTASADQRARLMMSTERLGRTTDRVKDSRRTMMETEEIGVSILQDLHGQRQSLLRAHETLHGVDDNIGKSKKILTDMTRRMNKNKWTIGAIIIALIAAIFIILYFKLTK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSDVFDGYE ------CCCCCCCHH	42.34	22223895
24	Phosphorylation	ASLSKKCSSAISLDG HHHCHHHCCCCCCCH	31.51	19880383
25	Phosphorylation	SLSKKCSSAISLDGE HHCHHHCCCCCCCHH	38.81	25561503
79	Phosphorylation	VKLREFKSDLNNFKT HHHHHHHHHHHHHHH	53.29	25561503
92	Phosphorylation	KTEVKRITSGQLNAA HHHHHHHHHHCCCHH	30.73	25561503
93	Phosphorylation	TEVKRITSGQLNAAA HHHHHHHHHCCCHHH	23.36	25561503
171	Phosphorylation	SLLRAHETLHGVDDN HHHHHHHHHHCCCCC	17.75	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VTI11_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VTI11_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VTI11_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SYP22_ARATH	VAM3	physical	10557242
SYP21_ARATH	SYP21	physical	10557242
YSL3_ARATH	YSL3	physical	22737156

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.