dbPTM

SYP21_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYP21_ARATH
UniProt AC	Q39233
Protein Name	Syntaxin-21
Gene Name	SYP21
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	279
Subcellular Localization	Prevacuolar compartment membrane Single-pass type IV membrane protein .
Protein Description	May function in the docking or fusion of transport vesicles with the prevacuolar membrane..
Protein Sequence	MSFQDLEAGTRSPAPNRFTGGRQQRPSSRGDPSQEVAAGIFRISTAVNSFFRLVNSIGTPKDTLELRDKLQKTRLQISELVKNTSAKLKEASEADLHGSASQIKKIADAKLAKDFQSVLKEFQKAQRLAAEREITYTPVVTKEIPTSYNAPELDTESLRISQQQALLLQSRRQEVVFLDNEITFNEAIIEEREQGIREIEDQIRDVNGMFKDLALMVNHQGNIVDDISSNLDNSHAATTQATVQLRKAAKTQRSNSSLTCLLILIFGIVLLIVIIVVLV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSFQDLEAG ------CCHHHCCCC	31.45	-
2	Phosphorylation	------MSFQDLEAG ------CCHHHCCCC	31.45	25561503
10	Phosphorylation	FQDLEAGTRSPAPNR HHHCCCCCCCCCCCC	34.71	25561503
12	Phosphorylation	DLEAGTRSPAPNRFT HCCCCCCCCCCCCCC	25.83	25561503
135	Phosphorylation	LAAEREITYTPVVTK HHHHCCCEEECEECC	19.31	23776212
136	Phosphorylation	AAEREITYTPVVTKE HHHCCCEEECEECCC	18.08	23776212
137	Phosphorylation	AEREITYTPVVTKEI HHCCCEEECEECCCC	10.85	23776212
141	Phosphorylation	ITYTPVVTKEIPTSY CEEECEECCCCCCCC	24.16	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYP21_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYP21_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYP21_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SYP51_ARATH	SYP51	physical	11739776
VCS_ARATH	VCS	physical	24556609
SNAA2_ARATH	ALPHA-SNAP2	physical	24556609
RL171_ARATH	AT1G27400	physical	24556609
VTI11_ARATH	SGR4	physical	24556609
NOP5B_ARATH	AT3G05060	physical	24556609
ADT1_ARATH	AAC1	physical	24556609
RL51_ARATH	ATL5	physical	24556609
NOP5A_ARATH	AT5G27120	physical	24556609
SRP14_ARATH	AT2G43640	physical	24556609
IF2B_ARATH	EIF2 BETA	physical	24556609
NACA4_ARATH	AT4G10480	physical	24556609
PDI21_ARATH	UNE5	physical	24556609
EXPB3_ARATH	EXPB3	physical	24556609
DOT2_ARATH	DOT2	physical	24556609
LECT2_ARATH	AT3G15356	physical	24556609
ACT12_ARATH	ACT12	physical	24556609
RS91_ARATH	AT5G15200	physical	24556609
FK151_ARATH	FKBP15-1	physical	24556609
SSRA_ARATH	AT2G21160	physical	24556609
NACA3_ARATH	NACA3	physical	24556609
RS241_ARATH	AT3G04920	physical	24556609
RL81_ARATH	EMB2296	physical	24556609
SYP51_ARATH	SYP51	physical	24556609
RL7A2_ARATH	AT3G62870	physical	24556609
RS41_ARATH	AT2G17360	physical	24556609
SRP09_ARATH	AT3G49100	physical	24556609
HMGB5_ARATH	HMGB5	physical	24556609
ANXD4_ARATH	ANNAT4	physical	24556609
VA711_ARATH	VAMP711	physical	24556609
CAMT4_ARATH	CCoAOMT1	physical	24556609
RPF2_ARATH	AT3G23620	physical	24556609
RL312_ARATH	AT4G26230	physical	24556609
MD36B_ARATH	FIB1	physical	24556609
MD37C_ARATH	HSP70	physical	24556609
VAP41_ARATH	MAMI	physical	24556609

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SYP21_ARATH

Related Literatures of Post-Translational Modification