RL51_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL51_ARATH
• UniProt AC: Q8LBI1
• Protein Name: 60S ribosomal protein L5-1
• Gene Name: ATL5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 301
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel..
• Protein Sequence: MVFVKSTKSNAYFKRYQVKFRRRRDGKTDYRARIRLINQDKNKYNTPKYRFVVRFTNKDIVAQIVSASIAGDIVKASAYAHELPQYGLTVGLTNYAAAYCTGLLLARRVLKMLEMDDEYEGNVEATGEDFSVEPTDSRRPFRALLDVGLIRTTTGNRVFGALKGALDGGLDIPHSDKRFAGFHKENKQLDAEIHRNYIYGGHVSNYMKLLGEDEPEKLQTHFSAYIKKGVEAESIEELYKKVHAAIRADPNPKKTVKPAPKQHKRYNLKKLTYEERKNKLIERVKALNGAGGDDDDEDDEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Acetylation	TKSNAYFKRYQVKFR CCCCCEEEEEEEEEE	37.20	21311031
112	Sulfoxidation	LARRVLKMLEMDDEY HHHHHHHHHCCCCCC	3.15	23289948
115	Sulfoxidation	RVLKMLEMDDEYEGN HHHHHHCCCCCCCCC	7.48	23289948
126	Phosphorylation	YEGNVEATGEDFSVE CCCCCEECCCCCCCC	27.83	29797451
135	Phosphorylation	EDFSVEPTDSRRPFR CCCCCCCCCCCCCHH	32.85	29797451
175	Phosphorylation	GGLDIPHSDKRFAGF CCCCCCCCCCCCCCC	39.20	25561503
199	Phosphorylation	EIHRNYIYGGHVSNY HHHHHHCHHHHHHHH	13.49	22074104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL51_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL51_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL51_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RL51_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.