PDI21_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDI21_ARATH
• UniProt AC: O22263
• Protein Name: Protein disulfide-isomerase like 2-1
• Gene Name: PDIL2-1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 361
• Subcellular Localization: Endoplasmic reticulum .
• Protein Description: Protein disulfide isomerase that may be required for proper pollen development, ovule fertilization and embryo development..
• Protein Sequence: MAKSQIWFGFALLALLLVSAVADDVVVLTDDSFEKEVGKDKGALVEFYAPWCGHCKKLAPEYEKLGASFKKAKSVLIAKVDCDEQKSVCTKYGVSGYPTIQWFPKGSLEPQKYEGPRNAEALAEYVNKEGGTNVKLAAVPQNVVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHCKSLAPTYEKVATVFKQEEGVVIANLDADAHKALGEKYGVSGFPTLKFFPKDNKAGHDYDGGRDLDDFVSFINEKSGTSRDSKGQLTSKAGIVESLDALVKELVAASEDEKKAVLSRIEEEASTLKGSTTRYGKLYLKLAKSYIEKGSDYASKETERLGRVLGKSISPVKADELTLKRNILTTFVASS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
243	Phosphorylation	RDLDDFVSFINEKSG CCHHHHHHHHHCCCC	22.02	22092075
296	Phosphorylation	SRIEEEASTLKGSTT HHHHHHHHHCCCCCH	37.24	19880383
297	Phosphorylation	RIEEEASTLKGSTTR HHHHHHHHCCCCCHH	39.27	19880383
338	Phosphorylation	LGRVLGKSISPVKAD HHHHHCCCCCCCCHH	26.88	21768351

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDI21_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDI21_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDI21_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PDI21_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.