SFGH_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SFGH_ARATH
• UniProt AC: Q8LAS8
• Protein Name: S-formylglutathione hydrolase
• Gene Name: SFGH
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 284
• Protein Description: Serine hydrolase involved in the detoxification of formaldehyde..
• Protein Sequence: MASGLSEIGSTKMFDGYNKRYKHFSETLGCSMTFSIYFPPSASSSHKSPVLYWLSGLTCTDENFIIKSGAQRAASTHGIALVAPDTSPRGLNVEGEADSYDFGVGAGFYLNATQEKWKNWRMYDYVVKELPKLLSENFSQLDTTKASISGHSMGGHGALTIYLRNLDKYKSVSAFAPITNPINCAWGQKAFTNYLGDNKAAWEEYDATCLISKYNNLSATILIDQGENDQFYPDQLLPSKFEEACKKVNAPLLLRLHPGYDHSYYFIATFIEDHISHHAQALEL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASGLSEIG ------CCCCCCCCC	16.59	22223895
59	Glutathionylation	YWLSGLTCTDENFII EEECCCEECCCCEEE	5.62	22833525
75	Phosphorylation	SGAQRAASTHGIALV CCHHHHHHCCCEEEE	21.69	25561503
76	Phosphorylation	GAQRAASTHGIALVA CHHHHHHCCCEEEEC	21.28	25561503
86	Phosphorylation	IALVAPDTSPRGLNV EEEECCCCCCCCCCC	39.30	29654922
87	Phosphorylation	ALVAPDTSPRGLNVE EEECCCCCCCCCCCC	21.71	30407730
123	Phosphorylation	KWKNWRMYDYVVKEL HHHHHHHHHHHHHHH	8.78	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SFGH_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SFGH_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SFGH_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of SFGH_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.