TOR1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TOR1_ARATH
• UniProt AC: Q9T041
• Protein Name: Microtubule-associated protein TORTIFOLIA1 {ECO:0000303|PubMed:15324671}
• Gene Name: TOR1 {ECO:0000303|PubMed:15324671}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 864
• Subcellular Localization: Cytoplasm, cytoskeleton . Bound to microtubules.
• Protein Description: Plant-specific microtubule-associated protein (MAP) that regulates the orientation of cortical microtubules and the direction of organ growth. [PubMed: 18577573 Determines microtubule organization by modulating microtubule severing]
• Protein Sequence: MSTPTTSGSAAKPTRPARSSSLATRSCSNSGSLTSFQAMVELKQKILTSISKLADRDTYQIAVEDLEKTIQSLTPETLPMFLNCLYDSCSDPKPAVKKECLHLLSYVCSLHCDSTAAHLTKIIAQIVKRLKDSDSGVRDACRDTIGALSGIYLKGKEEGTNTGSASLAVGLFVKPLFEAMGEQNKVVQSGASMCMARMVESAASPPVTSFQKLCPRICKLLSNSSFLAKASLLPVVSSLSQVGAIAPQSLESLLESIHDCLGSTDWVTRKAAAETLTALASHSSGLIKEKTDSTITVLETCRFDKIKPVRESVTEALQLWKKISGKYVDGASDDSKLSASEQLGSEKNGEKRSNLADLMKKEASDGSTLSPDSASKGKGCFPEKAVGLLKKKAPVLSDKDFNPEFFQRLERRQSVEVVVPRRCKNNDEEESGLDDLNAMGSSNRLKNTQADDKQVKGRFDGNGSQARTSGDDKAGVVNGKETPGHHAPVSNTDNQSEGSFTSNRGNWSAIQRQLLQLERQQTNLMNMLQEFIGGSHDSMVTLEGRVRGLERIVEDMARDLSISSGRRANLTAGFGKYNSFANYPTGKYNGRAPGERGSQTDGAMRGRMWNSDMADDWFIPPHAASRNGQAGPRRSPRSEQYENEHMGNGRRGWDNKASGTIRFGEGPSARSVWQASKDEATLEAIRVAGEDGAVPRPTRVAVAPEAEAMGDDDNEGQERDPIWVSWSNAMHSLRVGDIDAAYAEVLCAGDQHLVIKLMDKTGPSLDQMSNEIANEALNFISQFLLDHSLYDICLSWSQQLLELVLQDGADTFGVPMELKTEILYNLQDACSTMDPPEDWEGPAPEQLVVQLASVWEIDLQQFDK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	TRPARSSSLATRSCS CCCCCCCCCCCCCCC		28419593
332	Phosphorylation	GKYVDGASDDSKLSA CCCCCCCCCCCCCCH		30291188
335	Phosphorylation	VDGASDDSKLSASEQ CCCCCCCCCCCHHHH		30407730
338	Phosphorylation	ASDDSKLSASEQLGS CCCCCCCCHHHHHCC		30407730
340	Phosphorylation	DDSKLSASEQLGSEK CCCCCCHHHHHCCCC		25561503
345	Phosphorylation	SASEQLGSEKNGEKR CHHHHHCCCCCCCCC		30407730
364	Phosphorylation	DLMKKEASDGSTLSP HHHHHHCCCCCCCCC		19376835
367	Phosphorylation	KKEASDGSTLSPDSA HHHCCCCCCCCCCHH		19376835
368	Phosphorylation	KEASDGSTLSPDSAS HHCCCCCCCCCCHHC		19376835
370	Phosphorylation	ASDGSTLSPDSASKG CCCCCCCCCCHHCCC		30291188
373	Phosphorylation	GSTLSPDSASKGKGC CCCCCCCHHCCCCCC		19376835
375	Phosphorylation	TLSPDSASKGKGCFP CCCCCHHCCCCCCCH		19376835
414	Phosphorylation	QRLERRQSVEVVVPR HHHHHHCCCEEEEEC		30291188
496	Phosphorylation	VSNTDNQSEGSFTSN CCCCCCCCCCCCCCC		30291188
579	Phosphorylation	AGFGKYNSFANYPTG CCCCCCCCCCCCCCC		30291188
583	Phosphorylation	KYNSFANYPTGKYNG CCCCCCCCCCCCCCC		25561503
585	Phosphorylation	NSFANYPTGKYNGRA CCCCCCCCCCCCCCC		25561503
668	Phosphorylation	IRFGEGPSARSVWQA EEECCCCCHHHHHHH		29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TOR1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TOR1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TOR1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
THO4B_ARATH	AT5G02530	physical	21798944
KAN1_ARATH	KAN	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.