dbPTM

THO4B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	THO4B_ARATH
UniProt AC	Q8L719
Protein Name	THO complex subunit 4B
Gene Name	ALY2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	292
Subcellular Localization	Nucleus, nucleoplasm .
Protein Description	Export adapter involved in nuclear export of spliced and unspliced mRNA..
Protein Sequence	MSGGLDMSLDDIIKSNRKPTGSRGRGGIGGGNNTGGRGGSGSNSGPSRRFANRVGARTAPYSRPIQQQQAHDAMWQNDVFATDASVAAAFGHHQTAVVGGGSSIETGTKLYISNLDYGVSNEDIKELFSEVGDLKRYGIHYDRSGRSKGTAEVVFSRRGDALAAVKRYNNVQLDGKLMKIEIVGTNLSAPALPILATAQIPFPTNGILGNFNENFNGNFNGNFNGNFRGRGRGGFMGRPRGGGFGGGNFRGGRGARGRGGRGSGGRGRDENVSAEDLDAELDKYHKEAMETS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
2	Acetylation	------MSGGLDMSL ------CCCCCCCCH	22223895
2	Phosphorylation	------MSGGLDMSL ------CCCCCCCCH	19880383
8	Phosphorylation	MSGGLDMSLDDIIKS CCCCCCCCHHHHHHC	19880383
273	Phosphorylation	RGRDENVSAEDLDAE CCCCCCCCHHHHHHH	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of THO4B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of THO4B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of THO4B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FZR1_ARATH	CCS52A2	physical	20706207
THO4B_ARATH	AT5G02530	physical	21798944
THO4B_ARATH	AT5G02530	physical	19435936
THO4C_ARATH	AT1G66260	physical	19435936
IF4A1_ARATH	EIF4A1	physical	19435936
THO4D_ARATH	ALY4	physical	19435936
MGN_ARATH	MAGO	physical	19435936

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of THO4B_ARATH

Related Literatures of Post-Translational Modification