THO4C_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: THO4C_ARATH
• UniProt AC: Q94EH8
• Protein Name: THO complex subunit 4C
• Gene Name: ALY3 {ECO:0000303|PubMed:15299117}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 295
• Subcellular Localization: Nucleus, nucleoplasm . Nucleus, nucleolus .
• Protein Description: Export adapter involved in nuclear export of spliced and unspliced mRNA..
• Protein Sequence: MSDALNMTLDEIVKKSKSERSAAARSGGKGVSRKSGRGRGGPNGVVGGGRGGGPVRRGPLAVNTRPSSSFSINKLARRKRSLPWQNQNDLYEETLRAVGVSGVEVGTTVYITNLDQGVTNEDIRELYAEIGELKRYAIHYDKNGRPSGSAEVVYMRRSDAIQAMRKYNNVLLDGRPMKLEILGGNTESAPVAARVNVTGLNGRMKRSVFIGQGVRGGRVGRGRGSGPSGRRLPLQQNQQGGVTAGRGGFRGRGRGNGGGRGNKSGGRGGKKPVEKSAADLDKDLESYHAEAMNIS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSDALNMTL ------CCHHHHCCH		-
8	Phosphorylation	MSDALNMTLDEIVKK CCHHHHCCHHHHHHH		19880383
67	Phosphorylation	LAVNTRPSSSFSINK EECCCCCCCCCCHHH		25561503
68	Phosphorylation	AVNTRPSSSFSINKL ECCCCCCCCCCHHHH		25561503
69	Phosphorylation	VNTRPSSSFSINKLA CCCCCCCCCCHHHHH		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of THO4C_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of THO4C_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of THO4C_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of THO4C_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.