| UniProt ID | FZR1_ARATH | |
|---|---|---|
| UniProt AC | Q8VZS9 | |
| Protein Name | Protein FIZZY-RELATED 1 | |
| Gene Name | FZR1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 475 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for meristem organization and maintenance of quiescent center identity and stem cells.. | |
| Protein Sequence | MEEDESTTPKKKSDSQLNLPPSMNRPTVSLESRINRLIDSNHYHSPSKPIYSDRFIPSRSGSNFALFDLASSSPNKKDGKEDGAGSYASLLKTALFGPVTPEKSDVVNGFSPSGNIFRFKTETQRSLNLYPPFDSDVVSGVSPSPVKSPRKILRSPYKVLDAPALQDDFYLNLVDWSAQNVLAVGLGNCVYLWNACSSKVTKLCDLGVDETVCSVGWALRGTHLAIGTSSGTVQIWDVLRCKNIRTMEGHRLRVGALAWSSSVLSSGSRDKSILQRDIRTQEDHVSKLKGHKSEICGLKWSSDNRELASGGNDNKLFVWNQHSTQPVLRFCEHAAAVKAIAWSPHHFGLLASGGGTADRCIRFWNTTTNTHLNCVDTNSQVCNLVWSKNVNELVSTHGYSQNQIIVWKYPTMSKLATLTGHSYRVLYLAVSPDGQTIVTGAGDETLRFWNVFPSPKSQSRESEIGALSFGRTTIR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 86 | Phosphorylation | GKEDGAGSYASLLKT CCCCCCCHHHHHHHH | 19.59 | 19880383 | |
| 87 | Phosphorylation | KEDGAGSYASLLKTA CCCCCCHHHHHHHHH | 10.17 | 19880383 | |
| 126 | Phosphorylation | FKTETQRSLNLYPPF EEECCCHHCCCCCCC | 16.28 | 26811356 | |
| 135 | Phosphorylation | NLYPPFDSDVVSGVS CCCCCCCCCCCCCCC | 32.46 | 26811356 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FZR1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FZR1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FZR1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| APC4_SCHPO | cut20 | physical | 15970679 | |
| CDKA1_ARATH | CDC2 | physical | 15970679 | |
| CCB23_ARATH | CYCB2;3 | physical | 20407024 | |
| CD27B_ARATH | HBT | physical | 20706207 | |
| CDC23_ARATH | APC8 | physical | 20706207 | |
| CKS2_ARATH | CKS2 | physical | 20706207 | |
| CDC16_ARATH | APC6 | physical | 20706207 | |
| GIG1_ARATH | UVI4-LIKE | physical | 20706207 | |
| APC1_ARATH | EMB2771 | physical | 20706207 | |
| APC4_ARATH | AT4G21530 | physical | 20706207 | |
| APC5_ARATH | AT1G06590 | physical | 20706207 | |
| APC7_ARATH | AT2G39090 | physical | 20706207 | |
| APC10_ARATH | APC10 | physical | 20706207 | |
| APC2_ARATH | APC2 | physical | 20706207 | |
| PSMD6_ARATH | AT4G24820 | physical | 20706207 | |
| AB19G_ARATH | WBC19 | physical | 20706207 | |
| EF115_ARATH | AT5G07310 | physical | 20706207 | |
| RHM3_ARATH | RHM3 | physical | 20706207 | |
| THO4B_ARATH | AT5G02530 | physical | 20706207 | |
| TCPA_ARATH | TCP-1 | physical | 20706207 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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