PSMD6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSMD6_ARATH
• UniProt AC: Q93Y35
• Protein Name: 26S proteasome non-ATPase regulatory subunit 6 homolog
• Gene Name: RPN7
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 387
• Protein Description: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins..
• Protein Sequence: MDGGAEGSQQPHLILANKLFLLTHPDVPDIEKVQLKSEVLDFIRSHGMAPLYETLIASSVLDLDQSLLESMRAANEEELKKLDEKIADAEENLGESEVREAHLAKALYFIRISDKEKALEQLKLTEGKTVAVGQKMDVVFYTLQLAFFYMDFDLVSKSIDKAKKLFEEGGDWERKNRLKVYEGLYCMSTRNFKKAASLFLDSISTFTTYEIFPYETFIFYTVLTSIITLDRVSLKQKVVDAPEILTVLGKIPFLSEFLNSLYECQYKAFFSAFAGMAVQIKYDRYLYPHFRFYMREVRTVVYSQFLESYKSVTVEAMAKAFGVSVDFIDQELSRFIAAGKLHCKIDKVAGVLETNRPDAKNALYQATIKQGDFLLNRIQKLSRVIDL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDGGAEGS -------CCCCCCCC	11.03	20516081
311	Phosphorylation	QFLESYKSVTVEAMA HHHHHCCCCCHHHHH	18.13	25368622
313	Phosphorylation	LESYKSVTVEAMAKA HHHCCCCCHHHHHHH	21.51	25368622
324	Phosphorylation	MAKAFGVSVDFIDQE HHHHHCCCHHHHCHH	19.15	25368622
333	Phosphorylation	DFIDQELSRFIAAGK HHHCHHHHHHHHHCC	25.13	23820729

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSMD6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSMD6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSMD6_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PSMD6_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.