| UniProt ID | APC10_ARATH | |
|---|---|---|
| UniProt AC | Q9ZPW2 | |
| Protein Name | Anaphase-promoting complex subunit 10 | |
| Gene Name | APC10 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 192 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating the ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several other aspects of development. Involved in the control of endoreduplication.. | |
| Protein Sequence | MATESSESEEEGKISGGNYKLIIDDDLREMGKNAAWSVSSCKPGNGVTTLRDDNLETYWQSDGLQPHLINIQFQKKVKLQLVVLYVDFKLDESYTPSKISIRAGDGFHNLKEIKSVELVKPTGWVCLSLSGTDPRETFVNTFMLQIAILSNHLNGRDTHIRQIKVYGPRPNPIPHQPFQFTSMEFLTYSTLR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MATESSESEEEG ---CCCCCCCCCCCC | 34.74 | 25561503 | |
| 6 | Phosphorylation | --MATESSESEEEGK --CCCCCCCCCCCCC | 38.62 | 25561503 | |
| 8 | Phosphorylation | MATESSESEEEGKIS CCCCCCCCCCCCCCC | 52.86 | 25561503 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of APC10_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of APC10_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of APC10_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| APC2_ARATH | APC2 | physical | 20706207 | |
| CD27B_ARATH | HBT | physical | 20706207 | |
| CDC23_ARATH | APC8 | physical | 20706207 | |
| CDC16_ARATH | APC6 | physical | 20706207 | |
| PYM_ARATH | UVI4 | physical | 20706207 | |
| GIG1_ARATH | UVI4-LIKE | physical | 20706207 | |
| APC1_ARATH | EMB2771 | physical | 20706207 | |
| APC4_ARATH | AT4G21530 | physical | 20706207 | |
| APC5_ARATH | AT1G06590 | physical | 20706207 | |
| APC7_ARATH | AT2G39090 | physical | 20706207 | |
| CFIS2_ARATH | AT4G25550 | physical | 20706207 | |
| CD27A_ARATH | CDC27a | physical | 20706207 | |
| AB2E_ARATH | RLI2 | physical | 20706207 | |
| FZR3_ARATH | FZR3 | physical | 20706207 | |
| CDKA1_ARATH | CDC2 | physical | 20706207 | |
| EIF3C_ARATH | EIF3C | physical | 20706207 | |
| DRB4_ARATH | DRB4 | physical | 22545099 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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